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Tytuł pozycji:

Pain management during diagnostic office hysteroscopy in postmenopausal women: a randomized study.

Tytuł:
Pain management during diagnostic office hysteroscopy in postmenopausal women: a randomized study.
Autorzy:
Samy, A.
Nabil, H.
Abdelhakim, A. M.
Mahya, M. E.
Abdel-Latif, A. A.
Metwally, A. A.
Mahy, M E
Temat:
POSTMENOPAUSE
PAIN management
WOMEN'S studies
VISUAL analog scale
HYSTEROSCOPY
PLACEBOS
Źródło:
Climacteric; Aug2020, Vol. 23 Issue 4, p397-403, 7p
Czasopismo naukowe
Objective: This study aimed to compare efficacy and safety of lidocaine versus tramadol versus placebo in reducing the pain of diagnostic outpatient hysteroscopy (OH) in postmenopausal women.Materials and methods: This randomized double-blinded study included 156 menopausal women who received intrauterine lidocaine infusion or oral tramadol (50 mg) or placebo before diagnostic OH (52 women/group). Primary outcome was pain severity during the procedure using a 10-cm visual analog scale. Secondary outcomes were pain scores 10 and 30 min post procedure, satisfaction level, and ease of cervical entry.Results: Lidocaine had lower pain scores compared to placebo during and 10 min after the procedure (p < 0.001). Tramadol had lower pain scores than placebo during the procedure (p = 0.04), 10 min after the procedure (p = 0.03), and 30 min after the procedure (p = 0.04). Both lidocaine and tramadol resulted in an easier procedure than placebo (p < 0.001 and p = 0.04, respectively). Lidocaine had an easier cervical entry compared to tramadol (p = 0.004). Satisfaction scores in the lidocaine and tramadol groups were significantly higher than in the placebo group (p < 0.001).Conclusions: Lidocaine and tramadol were effective in reducing postmenopausal women-reported pain during and after diagnostic OH. However, lidocaine was better than tramadol in facilitating hysteroscope passage through the cervical canal and the reduction in pain levels with lidocaine was clinically relevant.Trial registration number: NCT03701984. [ABSTRACT FROM AUTHOR]
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