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Tytuł pozycji:

In vitro assessment of the potency of some Newcastle disease vaccine brands in Ibadan, Nigeria.

Tytuł :
In vitro assessment of the potency of some Newcastle disease vaccine brands in Ibadan, Nigeria.
Autorzy :
Okanlawon, A. A.
Ameen, S. A.
Kadir, R. A.
Ambali, H. M.
Baba, Y. A.
Azeez, O. M.
Owoade, A. A.
Pokaż więcej
Temat :
NEWCASTLE disease vaccines
CHICKEN diseases
POULTRY diseases
NEWCASTLE disease
VACCINE trials
DISEASE outbreaks
THERAPEUTICS
Alternatywny tytuł :
Évaluation in vitro de la puissance de certaines marques de vaccins contre la maladie de Newcastle à Ibadan, Nigéria. (French)
Źródło :
African Journal of Clinical & Experimental Microbiology; Oct2020, Vol. 21 Issue 4, p328-332, 5p
Terminy geograficzne :
IBADAN (Nigeria)
Abstract (English) :
Background: Newcastle disease (ND) is a very common and economically important disease of poultry. There is no drug for treatment of the disease during an outbreak in poultry flocks, and prevention by vaccination is one of the recommended control measures. However, post vaccination outbreaks have been observed on many occasions in chicken flocks and one of the causes has been attributed to possible failure of vaccine to confer immunity. This study was designed to evaluate the potency of ND vaccines available in Ibadan, Nigeria. Methodology: Haemagglutination (HA) technique and elution phenomenon were employed to evaluate the potency of ND vaccines randomly selected in Ibadan. A total of 45 vaccines comprising 9 brands and 5 different strains were selected for potency test. The vaccine brands included 'Vireo 116' (n=10), 'ABIC' (n=5), 'Biovac'(n=9), 'Nobilis'(n=3), 'NVRI'(n=12), 'R²B' (n=2), 'BAL-ND' (n=2), 'Forte dodge'(n=1) and 'Jovac' (n=1), while the vaccine strains in the brands included Lasota, B1, Clone, Komarov, Hitcher, and an unknown strain. Results: Thirty-five of the 45 (77.8%) ND vaccines tested had more than 4 HA titer (>64) and were therefore regarded as potent. All the 15 (100%) ND Lasota vaccine strain, 7 out of 10 (70%) ND Komarov strain, 4 out of 5 (80%) ND clone and 5 out of 8 (62.5%) ND B1 strains were potent. None of the ND brand 'R2B' vaccine as well as Hitchner strain from 'Nobilis' brand was potent, but all 5, 2, 1 and 1 vaccines tested from brands 'ABIC', 'BAL-ND', 'Fort dodge' and 'Jovac' respectively were potent. Similarly, 9 of 10, 6 of 9, 2 of 3 and 9 of 12 vaccine strains tested from brands 'Vireo 116', 'Biovac', 'Nobilis' and 'NVRI' were respectively potent. Conclusion: The occurrence of ND vaccines that are not potent in this study may be contributing to post vaccination failure. It is advisable to subject vaccines to potency test before use. [ABSTRACT FROM AUTHOR]
Czasopismo naukowe
Copyright of African Journal of Clinical & Experimental Microbiology is the property of AJCEM Lifeline Co. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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