-
Tytuł:
-
The added value of geriatric assessment in evaluating a patient's Health‐Related Quality‐of‐Life: A study in ≥70‐year‐old early‐stage invasive breast cancer patients.
-
Autorzy:
-
Quinten, Chantal
Kenis, Cindy
Hamaker, Marije
Coolbrandt, Annemarie
Brouwers, Barbara
Dal Lago, Lissandra
Neven, Patrick
Vuylsteke, Peter
Debrock, Guy
Van Den Bulck, Heidi
Smeets, Ann
Schöffski, Patrick
Wedding, Ulrich
Wildiers, Hans
-
Temat:
-
GERIATRIC assessment
BREAST tumors
CANCER patients
CHI-squared test
COMBINED modality therapy
CONFIDENCE intervals
LIFE skills
LONGITUDINAL method
MEDICAL cooperation
QUALITY of life
QUESTIONNAIRES
RESEARCH
RESEARCH funding
SELF-evaluation
STATISTICS
DATA analysis
MULTIPLE regression analysis
STATISTICAL models
DESCRIPTIVE statistics
OLD age
-
Źródło:
-
European Journal of Cancer Care; Sep2020, Vol. 29 Issue 5, p1-10, 10p
-
Terminy geograficzne:
-
BELGIUM
-
Objective: The objective of this study was to assess the relationship between geriatric assessment (GA) and health‐related Quality‐of‐Life (HRQOL) in older patients with breast cancer. Methods: Patients were assigned either to adjuvant chemotherapy (CTG) or to a control group (CG). Spearman rank coefficients (ρ) calculated correlations between HRQOL and GA at baseline, 3 months and 1 year. Multivariate regressions modelled the prognostic value of GA in evaluating of a patient's HRQOL and the accuracy of baseline GA in predicting HRQOL decline (change of ≥10 points). Results: The analysis included 57 patients in the CTG and 52 in the CG. Strong correlations (ρ ≥ 0.5) were reported between the EORTC QLQ‐C30 Physical Functioning Scale and Activities of Daily Living (ADL), Instrumental ADL (iADL) and Leuven Oncogeriatric Frailty Score Scale (LOFS). Multivariate models demonstrated that poor iADL, ADL and LOFS (CG) and ADL and iADL (CTG) contributed to a statistically (all p <.05) worse HRQOL. The relative gain in predicting 3‐month and 1‐year HRQOL decline was 24.1% and 4.7% (CG) and 6.1% and 18.3% (CTG). Conclusion: Our results show that the functional measures in the GA are strongly correlated with patient self‐reported functioning. Poor baseline GA has a modest probability of predicting HRQOL deterioration. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Cancer Care is the property of Hindawi Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)