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Tytuł:
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Personality dimensions of patients can change during the course of parkinson's disease.
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Autorzy:
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Boussac, Mathilde
Arbus, Christophe
Dupouy, Julia
Harroch, Estelle
Rousseau, Vanessa
Croiset, Aurélie
Ory-Magne, Fabienne
Rascol, Olivier
Moreau, Caroline
Rolland, Anne-Sophie
Maltête, David
Rouaud, Tiphaine
Meyer, Mylène
Drapier, Sophie
Giordana, Bruno
Anheim, Mathieu
Hainque, Elodie
Jarraya, Béchir
Benatru, Isabelle
Auzou, Nicolas
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Temat:
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PARKINSON'S disease
DEEP brain stimulation
DOPAMINERGIC neurons
PERSONALITY
PERSONALITY studies
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Źródło:
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PLoS ONE; 1/7/2021, Vol. 16 Issue 1, p1-11, 11p
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Background: Studies assessing personality dimensions by the "Temperament and Character Inventory" (TCI) have previously found an association between Parkinson's disease (PD) and lower Novelty Seeking and higher Harm Avoidance scores. Here, we aimed to describe personality dimensions of PD patients with motor fluctuations and compare them to a normative population and other PD populations. Methods: All PD patients awaiting Deep Brain Stimulation (DBS) answered the TCI before neurosurgery. Their results were compared to those of historical cohorts (a French normative population, a de novo PD population, and a PD population with motor fluctuations). Results: Most personality dimensions of our 333 included PD patients with motor fluctuations who are candidates for DBS were different from those of the normative population and some were also different from those of the De Novo PD population, whereas they were similar to those of another population of PD patients with motor fluctuations. Conclusions: During the course of PD, personality dimensions can change in parallel with the development of motor fluctuations, either due to the evolution of the disease and/or dopaminergic treatments. [ABSTRACT FROM AUTHOR]
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