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Tytuł:
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Multiple lentigines, myxoid tumours and endocrine overactivity; four cases of Carney's complex.
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Autorzy:
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Handley, J.
Carson, D.
Sloan, J.
Walsh, M.
Thornton, C.
Hadden, D.
Bingham, E. A.
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Temat:
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CUSHING'S syndrome
ENDOCRINE diseases
MYXOMA
ADENOMA
TUMORS
SERTOLI cells
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Źródło:
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British Journal of Dermatology; Apr1992, Vol. 126 Issue 4, p367-371, 5p
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Four patients with Carney's complex, one sporadic and three familial, are described. The sporadic case was a young male with centrofacial lentigines, who developed cyclical Cushing's syndrome secondary to bilateral pigmented nodular adrenocortical disease, two separate left atrial myxomas, and buccal mucosal myxomas. The three familial cases, who all had varying degrees of centrofacial/mucosal lentigines and cutaneous myxoid tumours, were a woman with myxoid mammary fibroadenomatosis and a left atrial myxoma, her daughter who developed a prolactin-secreting pituitary adenoma, and her son who had bilateral large-cell calcified Sertoli cell testicular tumours, and an axillary psammomatous melanotic schwannoma. [ABSTRACT FROM AUTHOR]
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