Regioselective Oxidative Cross-Coupling Reaction: Synthesis of Imidazo[1,2- a ]pyridine Fluorophores.

A rapid access to a series of N -heteroarene fluorophores has been developed on the basis of the palladium-catalyzed direct oxidative C–H/C–H coupling of imidazo[1,2- a ]pyridines with thiophenes/furans. The photophysical properties–structure relationship was systematically investigated. The resulting N -heteroarene fluorophores present color-tunable emissions (λem : 431–507 nm in CH2 Cl2) and high fluorescence quantum yields (up to 91% in CH2 Cl2). [ABSTRACT FROM AUTHOR]
Copyright of Synthesis is the property of Georg Thieme Verlag Stuttgart and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)