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Tytuł pozycji:

The risk of needle stick accidents during surgical procedures: HIV-1 viral load in blood and bone marrow.

Tytuł:
The risk of needle stick accidents during surgical procedures: HIV-1 viral load in blood and bone marrow.
Autorzy:
Regez, Rosa M.
Kleipool, Arthur E.
Speekenbrink, Ron G.
Frissen, P. H. Jos
Temat:
COMMUNITY health workers
HIV infection transmission
VIRAL load
INFECTIOUS disease transmission
RISK assessment
Źródło:
International Journal of STD & AIDS; Oct2005, Vol. 16 Issue 10, p671-672, 2p, 1 Chart
Czasopismo naukowe
Health-care workers are at risk to acquire HIV through occupational exposure to blood of HIV-infected patients. The mean risk after a percutaneous exposure is approximately 0.3%. A large inoculum and a source patient with a high plasma viral load increases the transmission risk. To ensure the safety of the operating team, we try to reduce HIV viral load in plasma prior to high-risk interventions (cardiothoracic and orthopaedic surgery). However, in 15.7% of the exposures occurring in the operating room, the possible source material is bone marrow. To make more accurate exposure risk assessments, we measured HIV-1 RNA in both plasma and bone marrow of five HIV-infected patients undergoing surgery. We found that the plasma viral load was not different from the viral load in bone marrow. [ABSTRACT FROM AUTHOR]
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