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Tytuł:
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Transient thyrotoxicosis from thyroiditis induced by sibutramine overdose: A case report.
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Autorzy:
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Kim, SK
Lee, SM
Yoo, SS
Hahm, JR
Jung, JH
Kim, HS
Kim, S
Chung, SI
Jung, TS
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Temat:
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HYPERTHYROIDISM
THYROIDITIS
SIBUTRAMINE
DRUG overdose
RADIOISOTOPES
THYROTROPIN
IODIDE peroxidase
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Źródło:
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Human & Experimental Toxicology; Aug2013, Vol. 32 Issue 8, p890-892, 3p, 1 Black and White Photograph
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Sibutramine is an antiobesity drug that inhibits the reuptake of serotonin and noradrenalin in the hypothalamus. A 37-year-old Korean man presented to the emergency room for the oral intake of 280 mg of sibutramine. The patient was in thyrotoxic state. The 99mTechnetium-pertechnetate thyroid scan showed irregular uptake of radioisotope and thyroid-stimulating hormone receptor antibody and thyroperoxidase antibody were negative. Thyroid function normalized after that. The patient had transient thyrotoxicosis with thyroiditis. We report a case of thyrotoxicosis accompanied by thyroiditis resulting from the intentional overdose of sibutramine. [ABSTRACT FROM AUTHOR]
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