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Tytuł pozycji:

EFFECT OF PHOTOBIOMODULATION ON HEAD AND NECK SQUAMOUS CELL CARCINOMA: A SYSTEMATIC REVIEW.

Tytuł :
EFFECT OF PHOTOBIOMODULATION ON HEAD AND NECK SQUAMOUS CELL CARCINOMA: A SYSTEMATIC REVIEW.
Autorzy :
SILVEIRA, FELIPE MARTINS
DE PAULI PAGLIONI, MARIANA
SANTOS-SILVA, ALAN ROGER
MARTINS, MANOELA DOMINGUES
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Źródło :
Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology; Jan2020, Vol. 129 Issue 1, pe146-e147, 2p
Czasopismo naukowe
This study aimed to conduct a systematic review to investigate the effects of photobiomodulation therapy (PBM) on head and neck squamous cell carcinoma (HNSCC) cells. MEDLINE/PubMed, EMBASE, Web of Science, and Scopus electronic databases were searched to identify relevant articles published up to December 2017. A manual search of bibliographies and reference lists of the included studies were also performed. Initially, 661 studies were gathered and 11 met the inclusion criteria (10 in vitro; 1 in vivo). Evaluated outcomes of the studies were mitotic index, cell proliferation, cell cycle analysis, apoptosis assay, proteins analysis, and morphologic examination. Five (50%) out of 10 in vitro studies demonstrated increased cell proliferation or stimulatory effect; 4 demonstrated inhibition, no proliferation, or lower levels of cell viability and 1 showed a decreased pro-osteoclastogenic potential of the cell lines studied after PBM. The in vivo study concluded that PBM inhibited tumor progression. Laser parameters were poorly described in the majority of the studies. There are a broad variation in the methodologies and controversial results regarding the effects of PBM on HNSCC cells. No clear conclusions could be obtained because of the scarce number of publications. Clinical trials and further in vivo studies are strongly recommended. [ABSTRACT FROM AUTHOR]
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