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Tytuł pozycji:

Disseminated Neospora caninum infection in a dog with severe colitis.

Tytuł:
Disseminated Neospora caninum infection in a dog with severe colitis.
Autorzy:
Curtis, Benjamin
Harris, Adam
Ullal, Tarini
Schaffer, Paula A.
Muñoz Gutiérrez, Juan
Temat:
NEOSPORA caninum
COLITIS
AUTOPSY
ULCERATIVE colitis
PULMONARY fibrosis
INFLAMMATORY bowel diseases
NEUROCYSTICERCOSIS
Źródło:
Journal of Veterinary Diagnostic Investigation; Nov2020, Vol. 32 Issue 6, p923-927, 5p
Czasopismo naukowe
A 12-y-old spayed female Schipperke dog with a previous diagnosis of inflammatory bowel disease was presented with a 2-mo history of severe colitis. The patient's condition progressed to hepatopathy, pneumonia, and dermatitis following management with prednisolone and dexamethasone sodium phosphate. Colonic biopsies identified severe necrosuppurative colitis with free and intracellular parasitic zoites. Postmortem examination confirmed extensive chronic-active ulcerative colitis, severe acute necrotizing hepatitis and splenitis, interstitial pneumonia, ulcerative dermatitis, myelitis (bone marrow), and mild meningoencephalitis with variable numbers of intracellular and extracellular protozoal zoites. PCR on samples of fresh colon was positive for Neospora caninum. Immunohistochemistry identified N. caninum tachyzoites in sections of colon, and a single tissue cyst in sections of brain. Administration of immunosuppressive drugs may have allowed systemic dissemination of Neospora from the intestinal tract. [ABSTRACT FROM AUTHOR]
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