Highlights: [•] Enzyme activity appears to be accelerated at a nanoparticle interface. [•] We examine this phenomenon in the context of the current literature. [•] Mechanisms that have been proposed to account for accelerated activity are highlighted. [•] Approaches to quantitative modeling of nanoparticle-associated enzyme activity are discussed. [•] When fully understood, this may represent an alternate mechanism to achieve enhanced enzymatic activity. [ABSTRACT FROM AUTHOR]
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