Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ
Tytuł pozycji:

Evaluation of exposure biomarkers in offshore workers exposed to low benzene and toluene concentrations

Tytuł :
Evaluation of exposure biomarkers in offshore workers exposed to low benzene and toluene concentrations
Autorzy :
Hopf, Nancy B.
Kirkeleit, Jorunn
Bråtveit, Magne
Succop, Paul
Talaska, Glenn
Moen, Bente E.
Pokaż więcej
Temat :
Adult
Air/analysis
Air Pollutants, Occupational/analysis
Benzene/analysis
Benzene Derivatives/analysis
Biomarkers/analysis
Chemical Industry
Environmental Monitoring
Extraction and Processing Industry
Female
Humans
Male
Middle Aged
Occupational Diseases/metabolism
Occupational Exposure/analysis
Petroleum
Solvents/analysis
Sorbic Acid/analogs & derivatives
Sorbic Acid/analysis
Toluene/analysis
Xylenes/analysis
Źródło :
International Archives of Occupational and Environmental Health, vol. 85, no. 3, pp. 261-271
Rok publikacji :
2012
Oryginalny identyfikator :
pmid: 21671104
Opis pliku :
application/pdf
Język :
English
ISSN :
1432-1246
DOI :
10.1007/s00420-011-0664-1
Purpose: Characterize ethylbenzene and xylene air concentrations, and explore the biological exposure markers (urinary t,t-muconic acid (t,t-MA) and unmetabolized toluene) among petroleum workers offshore. Offshore workers have increased health risks due to simultaneous exposures to several hydrocarbons present in crude oil. We discuss the pooled benzene exposure results from our previous and current studies and possible co-exposure interactions. Methods: BTEX air concentrations were measured during three consecutive 12-h work shifts among 10 tank workers, 15 process operators, and 18 controls. Biological samples were collected pre-shift on the first day of study and post-shift on the third day of the study. Results: The geometric mean exposure over the three work shifts were 0.02ppm benzene, 0.05ppm toluene, 0.03ppm ethylbenzene, and 0.06ppm xylene. Benzene in air was significantly correlated with unmetabolized benzene in blood (r=0.69, p<0.001) and urine (r=0.64, p<0.001), but not with urinary t,t-MA (r=0.27, p=0.20). Toluene in air was highly correlated with the internal dose of toluene in both blood (r=0.70, p<0.001) and urine (r=0.73, p<0.001). Co-exposures were present; however, an interaction of metabolism was not likely at these low benzene and toluene exposures. Conclusion: Urinary benzene, but not t,t-MA, was a reliable biomarker for benzene at low exposure levels. Urinary toluene was a useful biomarker for toluene exposure. Xylene and ethylbenzene air levels were low. Dermal exposure assessment needs to be performed in future studies among these workers

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies