Eikenella corrodens endocarditis and liver abscess in a previously healthy male, a case report
Nordholm, Anne Christine
Vøgg, Ruth Ottilia Birgitta
Anti-Bacterial Agents/therapeutic use
Liver Abscess, Pyogenic/diagnostic imaging
Gram-Negative Bacterial Infections/microbiology
Positron Emission Tomography Computed Tomography
Endocarditis, Bacterial/diagnostic imaging
Infectious and parasitic diseases
Nordholm, A C, Vøgg, R O B, Permin, H & Katzenstein, T 2018, ' Eikenella corrodens endocarditis and liver abscess in a previously healthy male, a case report ', BMC Infectious Diseases, vol. 18, no. 1, 35 . https://doi.org/10.1186/s12879-018-2949-4
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-5 (2018)
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Oryginalny identyfikator :
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BACKGROUND: Eikenella corrodens is one of the HACEK bacteria constituting part of the normal flora of the oropharynx, however, still an uncommon pathogen. We report a case of a large Eikenella corrodens liver abscess with simultaneously endocarditis in a previously healthy male.CASE PRESENTATION: A 49-year-old Danish man was admitted because of one-month malaise, fever, cough and unintentional weight loss. On admission there was elevated white blood cell count and C-reactive protein, as well as affected liver function tests. Initially pneumonia was suspected, but due to lack of improvement on pneumonia treatment, a PET-CT scan was performed, which showed a large multiloculated abscess in the liver. The abscess was drained using ultrasound guidance. Culture demonstrated Eikenella corrodens. Transesophageal echocardiography revealed aortic endocarditis. The patient was treated with antibiotics and abscess drainage, on which he slowly improved. He was discharged after 1.5 months of hospitalisation. On follow-up 2 months later, the patient was asymptomatic with normalized biochemistry and ultrasound showed complete regression of the abscess.CONCLUSIONS: This is the first case of documented Eikenella corrodens concurrent liver abscess and endocarditis. The case report highlights that Eikenella corrodens should be considered as a cause of liver abscess. Empirical treatment of pyogenic liver abscess will most often cover Eikenella corrodens, but the recommended treatment is a third generation cephalosporin or a fluoroquinolon. A multiloculated liver abscess may require drainage several times during treatment. The finding of Eikenella corrodens should elicit an echocardiography to diagnose endocarditis even in patients without clinical signs of endocarditis.
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