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Tytuł pozycji:

Evaluation of cone function by a handheld non-mydriatic flicker electroretinogram device

Tytuł :
Evaluation of cone function by a handheld non-mydriatic flicker electroretinogram device
Autorzy :
Nakamura N
Fujinami K
Mizuno Y
Noda T
Tsunoda K
Pokaż więcej
Temat :
RETevalTM
Flicker ERG
Cone dysfunction
Retina
Ophthalmology
RE1-994
Źródło :
Clinical Ophthalmology, Vol 2016, Iss Issue 1, Pp 1175-1185 (2016)
Wydawca :
Dove Medical Press, 2016.
Rok publikacji :
2016
Kolekcja :
LCC:Ophthalmology
Typ dokumentu :
article
Opis pliku :
electronic resource
Język :
English
ISSN :
1177-5483
Relacje :
https://www.dovepress.com/evaluation-of-cone-function-by-a-handheld-non-mydriatic-flicker-electr-peer-reviewed-article-OPTH; https://doaj.org/toc/1177-5483
Dostęp URL :
https://doaj.org/article/1da698b07153486180ec8863f5b45084
Prawa :
Journal Licence: CC BY-NC
Numer akcesji :
edsdoj.1da698b07153486180ec8863f5b45084
Czasopismo naukowe
Natsuko Nakamura,1 Kaoru Fujinami,1 Yoshinobu Mizuno,2 Toru Noda,2 Kazushige Tsunoda11Laboratory of Visual Physiology, Division of Vision Research, National Institute of Sensory Organs, 2Department of Ophthalmology, National Hospital Organization, National Tokyo Medical Center, Tokyo, JapanPurpose: Full-field electroretinograms (ERGs) are used to evaluate retinal function in patients with various types of hereditary and acquired retinal diseases. However, ERG recordings require relatively invasive procedures, including pupillary dilation and the use of contact lens electrodes. Thus, it would be helpful to have a simpler and noninvasive screening method. The purpose of this study was to determine whether a new, handheld, portable ERG device, RETeval™, can be used to screen patients for cone dysfunction.Patients and methods: Thirty-five eyes of 35 patients who had reduced cone responses ascertained by a conventional ERG system using contact lens electrodes were studied. The causative diseases included achromatopsia, cone dystrophy, cone-rod dystrophy, retinitis pigmentosa, choroidal dystrophy, autoimmune retinopathy, and Stargardt disease. The flicker ERGs were recorded with the RETeval™ under undilated conditions with skin electrodes (stimulus strength, 3.0 cd·s/m2; frequency, 28.3 Hz), and the responses were compared to that of 50 healthy eyes. The amplitudes and implicit times of the fundamental component of the flicker ERGs were analyzed in three age groups: Group A, ≤20 years; Group B, 21–40 years; and Group C, ≥41 years.Results: In all of the age groups, the amplitudes of the ERGs were significantly smaller and the implicit times significantly longer in patients with cone dysfunction than in the control eyes. All but one of the patients had flicker amplitudes lower than the mean −2.0 standard deviation of control eyes.Conclusion: The RETeval™ has a potential of being used to screen for cone dysfunction. The entire examination takes

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