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Tytuł pozycji:

Risk factors for maternal mortality associated with eclampsia presenting at a Nigerian tertiary hospital

Tytuł:
Risk factors for maternal mortality associated with eclampsia presenting at a Nigerian tertiary hospital
Autorzy:
Rabiu KA
Adewunmi AA
Ottun TA
Akinlusi FM
Adebanjo AA
Alausa TG
Temat:
maternal mortality
eclampsia
Nigeria
Gynecology and obstetrics
RG1-991
Źródło:
International Journal of Women's Health, Vol Volume 10, Pp 715-721 (2018)
Wydawca:
Dove Medical Press, 2018.
Rok publikacji:
2018
Kolekcja:
LCC:Gynecology and obstetrics
Typ dokumentu:
article
Opis pliku:
electronic resource
Język:
English
ISSN:
1179-1411
Relacje:
https://www.dovepress.com/risk-factors-for-maternal-mortality-associated-with-eclampsia-presenti-peer-reviewed-article-IJWH; https://doaj.org/toc/1179-1411
Dostęp URL:
https://doaj.org/article/ae1f93e52bb145af9437dd1a21d644d2  Link otwiera się w nowym oknie
Numer akcesji:
edsdoj.1f93e52bb145af9437dd1a21d644d2
Czasopismo naukowe
Kabiru Afolarin Rabiu,1 Adeniyi Abiodun Adewunmi,1 Tawakwalit Abimbola Ottun,1 Fatimat Motunrayo Akinlusi,1 Adewunmi Adeoye Adebanjo,2 Taiwo Ganiyat Alausa2 1Department of Obstetrics and Gynaecology, Lagos State University College of Medicine, Ikeja, Lagos State, Nigeria; 2Department of Obstetrics and Gynaecology, Lagos State University Teaching Hospital, Ikeja, Lagos State, Nigeria Background: Eclampsia remains a leading contributor to maternal mortality, particularly in developing countries, and remains a challenge even to the most experienced obstetrician. We aimed to determine the factors associated with maternal mortality in eclamptics at the Lagos State University Teaching Hospital (LASUTH), Nigeria, in order to suggest ways to prevent this avoidable tragedy. Materials and methods: Data were prospectively collected with the aid of a specially designed proforma from January 1, 2011 to December 31, 2012. Comparison was made between the patients who died (cases) and the survivors (control). Univariate and multivariate analyses were carried out using logistic regression. Results: The case fatality rate was 19.4%. Factors independently associated with mortality were as follows: period between onset of seizures to arrival in LASUTH >12 hours (adjusted OR=22.04; 95% CI=4.62–104.95; P=0.001), vaginal delivery (adjusted OR=10.96; 95% CI=2.54–47.27; P=0.0013), presence of aspiration pneumonitis (adjusted OR=7.77; 95% CI=2.37–25.46; P=0.0007), and presence of renal failure (adjusted OR=7.09; 95% CI=2.14–23.48; P=0.0014). The use of magnesium sulfate reduced the risk of mortality (adjusted OR=0.25; 95% CI=0.09–0.72; P=0.0104). Conclusion: Maternal mortality in patients with eclampsia was associated largely with preventable factors. The use of standard obstetric services, prompt referral of patients for definitive care, and the use of simplified dosing regimen of magnesium sulfate may improve its utilization and also improve maternal outcome. Keywords: maternal mortality, eclampsia, Nigeria
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