Huanhuan Huang,1 Huimei Yin,2 Wenxin Xu,1 Qi Wang,3 Mingzhao Xiao,4 Qinghua Zhao1 1Department of Nursing, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Department of Neurology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 3Department of Medical Informatics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 4Department of Urology, Urologist, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Qinghua Zhao, Department of Nursing, the First Affiliated Hospital of Chongqing Medical University, 1st Youyi Road, Chongqing, 400016, People’s Republic of China, Tel +86 023 89012206, Email qh20063@163.comPurpose: To design and develop a blood collection management workstation with high usability to reduce the risk of preanalytical errors and improve patient safety.Methods: A five-phase mobile application development lifecycle model (MADLC) and experience-based co-design (EBCD) were used for design and development. Subsequently, the blood collection management workstation was evaluated using the Chinese System Usability Scale (SUS) in a general ward setting from January to June 2021.Results: It was used on 2593 in-patients who underwent phlebotomy with 12,378 tubes being labeled. The rate of errors and meantime for blood sampling were decreased compared with the same period in the previous year. A total of 14 nurses agreed to participate in the evaluation, and the overall raw SUS score was 69.26 ± 10.39, which indicated above average results.Conclusion: The blood collection management workstation has shown the potential to decrease errors and improve working efficiency in a clinical setting. The study also identified some weaknesses, which will be amended in the future.Keywords: patient safety, identification, pre-analytical phase, phlebotomy, technology