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Title of the item:

Epidemiology of acute kidney injury in intensive care units in Beijing: the multi-center BAKIT study

Title :
Epidemiology of acute kidney injury in intensive care units in Beijing: the multi-center BAKIT study
Authors :
Li Jiang
Yibing Zhu
Xuying Luo
Ying Wen
Bin Du
Meiping Wang
Zhen Zhao
Yanyan Yin
Bo Zhu
Xiuming Xi
The Beijing Acute Kidney Injury Trial (BAKIT) workgroup
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Subject Terms :
Acute kidney injury
Renal replacement therapy
Critical care medicine
Diseases of the genitourinary system. Urology
Source :
BMC Nephrology, Vol 20, Iss 1, Pp 1-10 (2019)
Publisher :
BMC, 2019.
Publication Year :
Collection :
LCC:Diseases of the genitourinary system. Urology
Document Type :
File Description :
electronic resource
Language :
Relation :
Access URL :
Accession Number :
Academic Journal
Abstract Background Acute kidney injury (AKI) commonly occurs in intensive care units (ICUs), leading to adverse clinical outcomes and increasing costs. However, there are limited epidemiological data of AKI in the critically ill in Beijing, China. Methods In this prospective cohort study in 30 ICUs, we screened the patients up to 10 days after ICU admission. Characteristics and outcomes were compared between AKI and non-AKI, renal replacement therapy (RRT) and non-RRT patients. Nomograms of logistic regression and Cox regression were performed to examine potential risk factors for AKI and mortality. Results A total of 3107 patients were included in the final analysis. The incidence of AKI was 51.0%; stages 1 to 3 accounted for 23.1, 11.8, and 15.7%, respectively. The majority (87.6%) of patients with AKI developed AKI on the first 4 days after admission to the ICU. A total of 281 patients were treated with RRT. Continuous RRT with predilution, citrate for anticoagulation and femoral vein for vascular access was the most common RRT pattern (29.9%, 84 of 281). Patients with AKI were associated with longer ICU-LOS and higher mortality and costs (P

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