Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ
Tytuł pozycji:

Functional levels and MRI patterns of muscle involvement in upper limbs in Duchenne muscular dystrophy.

Tytuł :
Functional levels and MRI patterns of muscle involvement in upper limbs in Duchenne muscular dystrophy.
Autorzy :
Claudia Brogna
Lara Cristiano
Tommaso Tartaglione
Tommaso Verdolotti
Lavinia Fanelli
Luana Ficociello
Giorgio Tasca
Roberta Battini
Giorgia Coratti
Nicola Forcina
Roberto De Santis
Giulia Norcia
Sara Carnicella
Cesare Colosimo
Pierre Carlier
Marika Pane
Eugenio Mercuri
Pokaż więcej
Temat :
Medicine
Science
Źródło :
PLoS ONE, Vol 13, Iss 6, p e0199222 (2018)
Wydawca :
Public Library of Science (PLoS), 2018.
Rok publikacji :
2018
Kolekcja :
LCC:Medicine
LCC:Science
Typ dokumentu :
article
Opis pliku :
electronic resource
Język :
English
ISSN :
1932-6203
Relacje :
http://europepmc.org/articles/PMC6010282?pdf=render; https://doaj.org/toc/1932-6203
DOI :
10.1371/journal.pone.0199222
Dostęp URL :
https://doaj.org/article/35d372c288c24e94946bf7bc7aa78c48
Numer akcesji :
edsdoj.35d372c288c24e94946bf7bc7aa78c48
Czasopismo naukowe
The aim of the study was to evaluate the spectrum of upper limb functional activities and imaging finding in a cohort of patients affected by Duchenne muscular dystrophy. Thirty-one patients of age between 5 and 29 years were included in the study (17 ambulant and 14 non-ambulant). They were all assessed using the Performance of Upper Limb (PUL) test and muscle MRI of shoulder, arm and forearm in order to establish if the functional scores obtained at shoulder, mid and distal level related to specific patterns of involvement in each upper limb segment on muscle MRI. At shoulder level, latissimus dorsi, serratus anterior, infraspinatus and subscapularis were always involved, even in patients with full functional scores at shoulder level. Diffuse and severe involvement of all muscles was found in the patients with a PUL shoulder functional score of ≤ 5. At arm level biceps brachii, brachialis and triceps were generally concordantly involved or spared. Some degree of involvement could already be detected in patients with reduced scores on the PUL mid domain. They were generally severely involved in patients with functional scores less than 6 at mid-level. At distal level supinator and pronator muscles were often involved, followed by brachioradialis and, less frequently, by the muscles of the flexor compartment. The extensor muscles were generally completely spared. A diffuse and severe involvement was found only in patients who had very low scores (8 or below) on the PUL distal domain. The integrated use of functional scales and imaging allowed to establish patterns of involvement at each level, and the functional scores that were more frequently associated with diffuse and severe involvement.
Zaloguj się, aby uzyskać dostęp do pełnego tekstu.

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies