Influence of pregnancy on the natural history of chronic hepatitis B virus infection

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Tytuł:: Influence of pregnancy on the natural history of chronic hepatitis B virus infection
Autorzy:: CHEN Yuxin
Temat:: Diseases of the digestive system. Gastroenterology
RC799-869
Źródło:: Linchuang Gandanbing Zazhi, Vol 35, Iss 7, Pp 1430-1434 (2019)
Wydawca:: Editorial Department of Journal of Clinical Hepatology, 2019.
Rok publikacji:: 2019
Kolekcja:: LCC:Diseases of the digestive system. Gastroenterology
Typ dokumentu:: article
Opis pliku:: electronic resource
Język:: Chinese
ISSN:: 1001-5256
Relacje:: http://www.lcgdbzz.org/qk_content.asp?id=10002; https://doaj.org/toc/1001-5256
Dostęp URL:: https://doaj.org/article/3b3f0adbf14f43d8a9b34e21945d0499 Link otwiera się w nowym oknie
Numer akcesji:: edsdoj.3b3f0adbf14f43d8a9b34e21945d0499
: Czasopismo naukowe

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Chronic hepatitis B virus (HBV) infection is still a serious public health problem in China, and the HBsAg carrying rate reaches 6.0%-7.8% in pregnant women. Maternal immune system is suppressed during pregnancy, which may affect the natural history of HBV infection. At present, no consensus has been reached on the influence of pregnancy on the natural history of HBV infection. The article reviews the research advances in the influence of pregnancy on the natural history of HBV infection from the aspects of maternal immunosuppression during pregnancy and the effect of pregnancy on viral replication, HBeAg seroconversion, liver function, and liver disease progression. Pregnant women with chronic HBV infection should be closely monitored in clinical practice in terms of virological examination and liver function examination during pregnancy and postpartum.

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