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Tytuł pozycji:

Survival of prostate cancer patients in central and northern Denmark, 1998–2009

Tytuł:
Survival of prostate cancer patients in central and northern Denmark, 1998–2009
Autorzy:
Borre M
Erichsen R
Lund L
Larsen EH
Nørgaard M
Jacobsen JB
Temat:
Infectious and parasitic diseases
RC109-216
Źródło:
Clinical Epidemiology, Vol 2011, Iss Supplement 1, Pp 41-46 (2011)
Wydawca:
Dove Medical Press, 2011.
Rok publikacji:
2011
Kolekcja:
LCC:Infectious and parasitic diseases
Typ dokumentu:
article
Opis pliku:
electronic resource
Język:
English
ISSN:
1179-1349
Relacje:
http://www.dovepress.com/survival-of-prostate-cancer-patients-in-central-and-northern-denmark-1-a7919; https://doaj.org/toc/1179-1349
Dostęp URL:
https://doaj.org/article/d4b5c1285d60480494d6f2bbe0f297aa  Link otwiera się w nowym oknie
Numer akcesji:
edsdoj.4b5c1285d60480494d6f2bbe0f297aa
Czasopismo naukowe
Michael Borre1,2, Rune Erichsen1, Lars Lund3, Erik Højkjær Larsen4, Mette Nørgaard1, Jacob Bonde Jacobsen11Department of Clinical Epidemiology, Aarhus University Hospital, Denmark; 2Department of Urology, Aarhus University Hospital, Skejby, Denmark; 3Department of Urology, Region Hospital Viborg, Denmark; 4Department of Urology, Aarhus University Hospital, Aalborg, DenmarkObjective: Prostate cancer is the most common noncutaneous cancer among Danish men. During the last decade, use of prostate specific antigen (PSA) testing has increased, and in clinically localized prostate cancer, curative intended treatment has gained a footing. Our aim was to examine possible changes in the short- and long-term survival of patients with prostate cancer during 1998–2009.Study design and setting: From two Danish regions (population, 1.8 million) we included all patients (N = 10,547) with an incident diagnosis of prostate cancer retrieved from the Danish National Registry of Patients. We determined survival after 1, 3, and 5 years, stratified by age, and estimated mortality rate ratios (MRRs) using Cox proportional hazard regression to assess changes over time, controlling for age.Results: During the study period, the annual number of incident prostate cancer patients more than doubled, and the median age at diagnosis decreased from 74 to 70 years. The survival improved over the study period, particularly in the last half of the period (2004–2009). Thus, 1-year survival increased from 80% (1998–2000) to 90% (2007–2009), corresponding to an age-adjusted MRR of 0.54 (95% confidence interval CI: 0.46–0.63). The expected increase in 3- and 5-year survival was even more pronounced: 47%–73% and 34%–60%, respectively. This corresponded to a 3-year age-adjusted MRR of 0.46 (95% CI: 0.42–0.51) and a 5-year MRR of 0.50 (95% CI: 0.46–0.54). The 1-, 3-, and 5-year overall survival increased in all age groups (

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