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Tytuł pozycji:

Pre-stroke adherence to a Mediterranean diet pattern is associated with lower acute ischemic stroke severity: a cross-sectional analysis of a prospective hospital-register study

Tytuł:
Pre-stroke adherence to a Mediterranean diet pattern is associated with lower acute ischemic stroke severity: a cross-sectional analysis of a prospective hospital-register study
Autorzy:
Pablo M. Lavados
Enrico Mazzon
Alexis Rojo
Alejandro M. Brunser
Verónica V. Olavarría
Temat:
Mediterranean diet
Adherence
Ischemic stroke
Acute stroke
Severity
Neurology. Diseases of the nervous system
RC346-429
Źródło:
BMC Neurology, Vol 20, Iss 1, Pp 1-8 (2020)
Wydawca:
BMC, 2020.
Rok publikacji:
2020
Kolekcja:
LCC:Neurology. Diseases of the nervous system
Typ dokumentu:
article
Opis pliku:
electronic resource
Język:
English
ISSN:
1471-2377
Relacje:
http://link.springer.com/article/10.1186/s12883-020-01824-y; https://doaj.org/toc/1471-2377
DOI:
10.1186/s12883-020-01824-y
Dostęp URL:
https://doaj.org/article/4d3ec8cefa4e471ab012893999ee16b9  Link otwiera się w nowym oknie
Numer akcesji:
edsdoj.4d3ec8cefa4e471ab012893999ee16b9
Czasopismo naukowe
Abstract Background High adherence to a Mediterranean Diet is associated with reduced incidence and mortality of acute ischemic stroke (AIS) but may also be associated with severity. Our purpose was to investigate the association of adherence to a Mediterranean diet and severity in a prospective hospital register of AIS patients. Methods We included AIS patients admitted from February 2017 to July 2019. All were assessed by a neurologist with a standard stroke protocol, including NIHSS. Adherence to Mediterranean diet was prospectively measured by the 14-point Mediterranean Diet Adherence Screener (MEDAS) and defined as low (0–6 points) or high (7–14 points). Demographic and clinical characteristics were compared by group with univariate analysis. A Generalized Linear Model (GLM) was used to investigate the association of admission NIHSS as a continuous ordinal variable and an ordinal logistic regression (OLR) analysis to determine the independent association of the NIHSS quartiles with adherence to Mediterranean diet. Results Three hundred sixty-eight patients were included, mean age 68.3 (17.7), 158 (42.9%) females. The median NIHSS score was 3 (IQR 1–9) and the median MEDAS score was 6 (IQR 4.5–8). Patients with high MEDAS scores had significantly lower; admission NIHSS scores, sedentary lifestyle, body mass index, total and LDL cholesterol levels, but higher alcohol consumption. After adjustments, high adherence to Mediterranean diet remained independently associated with lower stroke severity both in the GLM (β coefficient = − 0.19, p = 0.01) and in the OLR model (OR for lower NIHSS quartiles 0.6 (95% CI 0.37–0.98, p = 0.04). Conclusions Higher pre-stroke adherence to a Mediterranean diet is independently associated with lower AIS severity.
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