Rapid HIV disease progression following superinfection in an HLA-B*27:05/B*57:01-positive transmission recipient - OpacWWW

Tytuł:: Rapid HIV disease progression following superinfection in an HLA-B*27:05/B*57:01-positive transmission recipient
Autorzy:: Jacqui Brener
Astrid Gall
Jacob Hurst
Rebecca Batorsky
Nora Lavandier
Fabian Chen
Anne Edwards
Chrissy Bolton
Reena Dsouza
Todd Allen
Oliver G. Pybus
Paul Kellam
Philippa C. Matthews
Philip J. R. Goulder
Temat:: HIV-1
HLA
CTL response
Transmission pair
Superinfection
Ultra-deep sequencing
Immunologic diseases. Allergy
RC581-607
Źródło:: Retrovirology, Vol 15, Iss 1, Pp 1-13 (2018)
Wydawca:: BMC, 2018.
Rok publikacji:: 2018
Kolekcja:: LCC:Immunologic diseases. Allergy
Typ dokumentu:: article
Opis pliku:: electronic resource
Język:: English
ISSN:: 1742-4690
Relacje:: http://link.springer.com/article/10.1186/s12977-018-0390-9; https://doaj.org/toc/1742-4690
DOI:: 10.1186/s12977-018-0390-9
Dostęp URL:: https://doaj.org/article/5fc6d4b84d414835beab40dcb90f9e9a Link otwiera się w nowym oknie
Numer akcesji:: edsdoj.5fc6d4b84d414835beab40dcb90f9e9a
: Czasopismo naukowe

Pełny tekst

Abstract Background The factors determining differential HIV disease outcome among individuals expressing protective HLA alleles such as HLA-B*27:05 and HLA-B*57:01 remain unknown. We here analyse two HIV-infected subjects expressing both HLA-B*27:05 and HLA-B*57:01. One subject maintained low-to-undetectable viral loads for more than a decade of follow up. The other progressed to AIDS in

Zaloguj się, aby uzyskać dostęp do pełnego tekstu.

Informacja

Rapid HIV disease progression following superinfection in an HLA-B27:05/B57:01-positive transmission recipient