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Tytuł pozycji:

Long-Term Opioid Therapy in Spine Center Outpatients: Protocol for the Spinal Pain Opioid Cohort (SPOC) Study

Tytuł :
Long-Term Opioid Therapy in Spine Center Outpatients: Protocol for the Spinal Pain Opioid Cohort (SPOC) Study
Autorzy :
Manniche, Claus
Stokholm, Lonny
Ravn, Sophie L
Andersen, Tonny E
Brandt, Lars PA
Rubin, Katrine H
Schiøttz-Christensen, Berit
Andersen, Lars L
Skousgaard, Søren G
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Temat :
Computer applications to medicine. Medical informatics
Źródło :
JMIR Research Protocols, Vol 9, Iss 8, p e21380 (2020)
Wydawca :
JMIR Publications, 2020.
Rok publikacji :
Kolekcja :
LCC:Computer applications to medicine. Medical informatics
Typ dokumentu :
Opis pliku :
electronic resource
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Relacje :;
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Numer akcesji :
Czasopismo naukowe
BackgroundSpinal pain is the leading cause of patient-years lived with chronic pain and disability worldwide. Although opioids are well documented as an effective short-term pain-relieving medication, more than a few weeks of treatment may result in a diminishing clinical effect as well as the development of addictive behavior. Despite recognition of opioid addiction in pain patients as a major problem commonly experienced in the clinic, no reference material exists on the scope of long-term problems in novel opioid users and the link to clinical outcomes. ObjectiveThe main aims of this study are to describe baseline and follow-up characteristics of the Spinal Pain Opioid Cohort (SPOC), to evaluate the general use of opioids in spinal pain when an acute pain episode occurs, and to demonstrate the prevalence of long-term opioid therapy (LTOT). MethodsProspective clinical registry data were collected from an outpatient spine center setting during 2012-2013 including patients with a new spinal pain episode lasting for more than 2 months, aged between 18 and 65 years who had their first outpatient visit in the center. Variables include demographics, clinical data collected in SpineData, the Danish National Patient Register, and The Danish National Prescription Registry. The primary outcome parameter is long-term prescription opioid use registered from 4 years before the first spine center visit to 5 years after. ResultsThis is an ongoing survey. It is estimated that more than 8000 patients fulfill the SPOC inclusion criteria. In 2019, we began the intellectual process of identifying the most relevant supplementary data available from the wide range of existing national registries available in Denmark. We have now begun merging SpineData with relevant opioid data from Danish national registers and will continue to extract data up to 2021-2022. We will also be looking at data regarding somatic or psychiatric hospitalization patterns, patient usage of health care resources, as well as their working status and disability pensions. ConclusionsTo our knowledge, this survey will be the first to document the scope of long-term problems regarding LTOT and opioid addiction following new spinal pain episodes and comparing descriptive follow-up data between substance users and nonusers. Trial RegistrationISRCTN Registry ISRCTN69685117; International Registered Report Identifier (IRRID)DERR1-10.2196/21380

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