Simultaneous copy number losses within multiple subtelomeric regions in early-onset type 2 diabetes mellitus.

Szczegóły
Opis

Tytuł:: Simultaneous copy number losses within multiple subtelomeric regions in early-onset type 2 diabetes mellitus.
Autorzy:: Shinjiro Kodama
Tetsuya Yamada
Junta Imai
Shojiro Sawada
Kei Takahashi
Sohei Tsukita
Keizo Kaneko
Kenji Uno
Yasushi Ishigaki
Yoshitomo Oka
Hideki Katagiri
Temat:: Medicine
Science
Źródło:: PLoS ONE, Vol 9, Iss 4, p e88602 (2014)
Wydawca:: Public Library of Science (PLoS), 2014.
Rok publikacji:: 2014
Kolekcja:: LCC:Medicine
LCC:Science
Typ dokumentu:: article
Opis pliku:: electronic resource
Język:: English
ISSN:: 1932-6203
Relacje:: http://europepmc.org/articles/PMC3977841?pdf=render; https://doaj.org/toc/1932-6203
DOI:: 10.1371/journal.pone.0088602
Dostęp URL:: https://doaj.org/article/805aba361d304c4bb96a590a26444e14 Link otwiera się w nowym oknie
Numer akcesji:: edsdoj.805aba361d304c4bb96a590a26444e14
: Czasopismo naukowe

Pełny tekst

Genetic factors play very important roles in the onset and progression of type 2 diabetes mellitus (T2DM). However, the genetic factors correlating with T2DM onset have not as yet been fully clarified. We previously found that copy number losses in the subtelomeric region on chromosome 4p16.3 were detected in early-onset Japanese T2DM patients (onset age

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