Bioprosthesis in aortic valve replacement: long-term inflammatory response and functionality

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Tytuł:: Bioprosthesis in aortic valve replacement: long-term inflammatory response and functionality
Autorzy:: Julio Iván Farjat-Pasos
Jesús Vargas-Barrón
Huitzilihuitl Saucedo-Orozco
Ricardo Márquez-Velazco
Karla Susana Martinez-Zavala
Valentin Jiménez-Rojas
Sergio Andres Criales-Vera
Jose Antonio Arias-Godínez
Giovanni Fuentevilla-Alvarez
Veronica Guarner-Lans
Israel Perez-Torres
Gabriela Melendez-Ramirez
Tomas Efrain Sanchez Perez
Maria Elena Soto
Temat:: Diseases of the circulatory (Cardiovascular) system
RC666-701
Źródło:: Open Heart, Vol 9, Iss 2 (2022)
Wydawca:: BMJ Publishing Group, 2022.
Rok publikacji:: 2022
Kolekcja:: LCC:Diseases of the circulatory (Cardiovascular) system
Typ dokumentu:: article
Opis pliku:: electronic resource
Język:: English
ISSN:: 2053-3624
Relacje:: https://openheart.bmj.com/content/9/2/e002065.full; https://doaj.org/toc/2053-3624
DOI:: 10.1136/openhrt-2022-002065
Dostęp URL:: https://doaj.org/article/ee80cb9339434aaf9507b1f8933683cc Link otwiera się w nowym oknie
Numer akcesji:: edsdoj.80cb9339434aaf9507b1f8933683cc
: Czasopismo naukowe

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Background The evaluation of long-term inflammatory response and function in postoperative patients with aortic valve replacement (AVR) deserves special analysis because it is important to try to prevent reoperation and improve durability and functionality of the prostheses. It is our objectiveMethods In this study, we included a cohort of patients with aortic valve damage treated by AVR with mechanical prosthesis, bio prosthesis and we included a control group.Results We found that IL-4 and osteopontin levels were higher in patients with mechanical vs biological prostheses (p=0.01 and p=0.04, respectively), osteoprotegerin (OPG) levels were decreased (p=0.01), women had lower levels of ET-1 and IL-6, (p=0.02) (p=0.04), respectively. Patients older than 60 years had decreased levels of IL-1ß p

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