Information

Dear user, the application need JavaScript support. Please enable JavaScript in your browser.

You are browsing as a GUEST
Title of the item:

Cytologic assessment of dynamics of reparative processes in the experimental conditionally aseptic wound under the action of complex preparation based on chitosan and metal nanoparticles

Title :
Cytologic assessment of dynamics of reparative processes in the experimental conditionally aseptic wound under the action of complex preparation based on chitosan and metal nanoparticles
Authors :
Konyuchenko Е.А.. Zhandarova L.F.
Babushkina I.V.
Gladkova E.V.
Mamonova I.A.
Belova S.V.
Karyakina E.V.
Show more
Subject Terms :
chitosan
cytologic assessment
metal nanoparticles
reparative regeneration
wound
Medicine (General)
R5-920
Source :
Saratovskij Naučno-medicinskij Žurnal, Vol 9, Iss 4, Pp 629-632 (2013)
Publisher :
Saratov State Medical University, 2013.
Publication Year :
2013
Collection :
LCC:Medicine (General)
Document Type :
article
File Description :
electronic resource
Language :
Russian
ISSN :
2076-2518
Relation :
http://www.ssmj.ru/system/files/2013-04_629-632.pdf; https://doaj.org/toc/2076-2518
Access URL :
https://doaj.org/article/a8822874e74a4b26ba68d12dc2bc0cd8
Rights :
Journal Licence: CC BY-NC
Accession Number :
edsdoj.8822874e74a4b26ba68d12dc2bc0cd8
Academic Journal
Objective: assessment of dynamics of reparative processes with the help of cytological examination of the preparations obtained from a conditionally aseptic wound under the action of a complex preparation based on biopolymer chitosan and metal nanoparticles. Material and Methods. A conditionally aseptic wound was simulated in 40 white outbred rats. In comparison and experimental groups cytologic assessment of dynamics of reparative processes was carried out. A number of neutrophilic leukocytes and fibroblastic row perl 00 cells in the preparations is recorded on the 3rd, 5th, 7th, 10th, 14th day from the moment of formation of the wound with the use of the immersion objective. Results. It is established, that in the comparison group the cytologic pattern of impression smear was characterized by decrease in neutrophilic leukocytes and increase in fibroblastic row cells by the 14th day from the moment of formation of the wound. In the experimental group (the use of a complex preparation) more intensive reduction of neutrophilic leukocytes and a significant increase in fibroblastic row cells by the 10th day and a complete healing by the 14th day from the moment of formation of the wound has been determined. Conclusion. When treated by a complex preparation based of biopolymer chitosan and metal nanoparticles earlier occurrence of fibroblastic row cells in preparations and a significant decrease in quantity of neutrophilic leukocytes have been observed.

We use cookies to help identify your computer so we can tailor your user experience, track shopping basket contents and remember where you are in the order process.