The effects of erythropoietin on neurogenesis after ischemic stroke

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Opis

Tytuł:: The effects of erythropoietin on neurogenesis after ischemic stroke
Autorzy:: Si-Jia Zhang, Yu-Min Luo, Rong-Liang Wang
Temat:: erythropoietin
neurogenesis
ischemic stroke
clinical translation
neurology
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Źródło:: Journal of Integrative Neuroscience, Vol 19, Iss 3, Pp 561-570 (2020)
Wydawca:: IMR Press, 2020.
Rok publikacji:: 2020
Kolekcja:: LCC:Neurosciences. Biological psychiatry. Neuropsychiatry
Typ dokumentu:: article
Opis pliku:: electronic resource
Język:: English
ISSN:: 1757-448X
Relacje:: https://jin.imrpress.com/fileup/1757-448X/PDF/1601427350539-417982196.pdf; https://doaj.org/toc/1757-448X
DOI:: 10.31083/j.jin.2020.03.4
Dostęp URL:: https://doaj.org/article/96d91b12f3b340b88ea21876ea7af54b Link otwiera się w nowym oknie
Numer akcesji:: edsdoj.96d91b12f3b340b88ea21876ea7af54b
: Czasopismo naukowe

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Erythropoietin has been researched for its neuroprotective effects in ischemic stroke for over 30 years. Although erythropoietin can cause side effects that need to be controlled, it has been suggested to be effective in enhancing the prognosis of patients who are out of the therapeutic time window and have not received recombinant tissue plasminogen activator therapy. Studies on the mechanism of the function of erythropoietin have shown that it has various protective effects in ischemic brain injury after stroke, including promoting neurogenesis. In this review, we discuss the effects of erythropoietin on neurogenesis after ischemic brain injury and provide references for effective treatments for ischemic stroke, which is one of the leading causes of death worldwide.

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