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Tytuł pozycji:

Chest Computed Tomography findings associated with severity and mortality in patients with COVID-19

Tytuł:
Chest Computed Tomography findings associated with severity and mortality in patients with COVID-19
Autorzy:
Jheferson Contreras-Grande
Vanessa Pineda-Borja
Hubertino Díaz
Renzo J.C. Calderon-Anyosa
Bertha Rodríguez
María Morón
Temat:
covid-19
sars-cov-2
neumonía
tomografía
índice de severidad de enfermedad
mortalidad
Medicine
Medicine (General)
R5-920
Źródło:
Revista Peruana de Medicina Experimental y Salud Pública, Vol 38, Iss 2, Pp 206-13 (2021)
Wydawca:
Instituto Nacional de Salud, 2021.
Rok publikacji:
2021
Kolekcja:
LCC:Medicine
LCC:Medicine (General)
Typ dokumentu:
article
Opis pliku:
electronic resource
Język:
Spanish; Castilian
ISSN:
1726-4634
1726-4642
Relacje:
https://rpmesp.ins.gob.pe/rpmesp/article/view/6562; https://doaj.org/toc/1726-4634; https://doaj.org/toc/1726-4642
DOI:
10.17843/rpmesp.2021.382.6562
Dostęp URL:
https://doaj.org/article/aabd368829b044dfa9c1d4b3c60ddd20  Link otwiera się w nowym oknie
Numer akcesji:
edsdoj.bd368829b044dfa9c1d4b3c60ddd20
Czasopismo naukowe
Objectives: To determine chest CT findings associated with severity and mortality in patients with COVID-19 from the Hospital Nacional Edgardo Rebagliati Martins (HNERM) and propose cut-off values for a tomographic severity score (TSS). Materials and Methods: A retrospective cohort study was conducted in 254 patients with COVID-19 who underwent chest CT as part of their initial evaluation at the emergency room; they were classified according to clinical severity. Main tomographic findings were described. A multivariate analysis with logistic regression was carried out to determine association with clinical severity, the Cox model was used to evaluate mortality, and ROC curves were elaborated to assess cutoff values for the TSS. Results: CT findings associated with clinical severity were the following: diffuse pattern (OR: 3.23, 95% CI: 1.46-7.14), crazy-paving pattern (OR: 2.48; 95% CI: 1.08-5.68), and high TSS value (OR: 1.73; 95% CI: 1.49-2.02). The crazy-paving pattern (HR: 1.78; 95% CI: 1.03-3.06) and a high TSS value (HR: 1.33; 95% CI: 1.20-1.48) were found to be associated with mortality. A value of 7 in the TSS showed a sensibility of 94.4% and a specificity of 100% for moderate disease, and a value of 13 showed a sensibility of 84.9% and a specificity of 70.6% for severe disease. Conclusions: The diffuse pattern is associated with higher clinical severity. The crazy-paving pattern and a high TSS value are associated with higher clinical severity and mortality. We propose TSS cutoff values of 7 and 13 for moderate and severe disease, respectively.

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