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Title of the item:

Quercetin-Based Nanocomposites as a Tool to Improve Dental Disease Management

Title :
Quercetin-Based Nanocomposites as a Tool to Improve Dental Disease Management
Authors :
Giuseppe Angellotti
Denise Murgia
Giuseppina Campisi
Viviana De Caro
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Subject Terms :
antibacterial effect
dental disease
dental implant
osteoinductive effect
quercetin scaffold
Biology (General)
Source :
Biomedicines, Vol 8, Iss 504, p 504 (2020)
Publisher :
MDPI AG, 2020.
Publication Year :
Collection :
LCC:Biology (General)
Document Type :
File Description :
electronic resource
Language :
Relation :;
Access URL :
Accession Number :
Academic Journal
The restoration and prosthetic rehabilitation of missing teeth are commonly performed using dental implants, which are extremely effective and long-lasting techniques due to their osteointegration ability with the preimplant tissues. Quercetin is a phytoestrogen-like flavonoid well known for its several positive effects on human health, mostly linked to the anti-inflammatory, antioxidant, and antibacterial activities against both Gram-positive and Gram-negative bacteria. Moreover, many studies in dentistry and the maxillofacial fields have highlighted the positive effects of quercetin on osteogenesis, acting on osteoblast activity and angiogenetic process, and promoting soft and hard tissue regeneration. This review focuses on the role of quercetin on the healing and restoration of bony defects, considering the experimental findings of its application both in vitro and in vivo as a mere compound or in association with scaffolds and dental implants having functionalized surfaces.

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