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Tytuł pozycji:

Preliminary Research of Relationship between Acute Peritonitis and Celiac Primo Vessels

Tytuł :
Preliminary Research of Relationship between Acute Peritonitis and Celiac Primo Vessels
Autorzy :
Xiaoyu Wang
Hong Shi
Jingjing Cui
Wanzhu Bai
Wei He
Hongyan Shang
Yangshuai Su
Juanjuan Xin
Xianghong Jing
Bing Zhu
Pokaż więcej
Temat :
Other systems of medicine
RZ201-999
Źródło :
Evidence-Based Complementary and Alternative Medicine, Vol 2013 (2013)
Wydawca :
Hindawi Limited, 2013.
Rok publikacji :
2013
Kolekcja :
LCC:Other systems of medicine
Typ dokumentu :
article
Opis pliku :
electronic resource
Język :
English
ISSN :
1741-427X
1741-4288
Relacje :
https://doaj.org/toc/1741-427X; https://doaj.org/toc/1741-4288
DOI :
10.1155/2013/569161
Dostęp URL :
https://doaj.org/article/f88d4cf90cfd4db19e7e750b4e9afce3
Prawa :
Journal Licence: CC BY
Numer akcesji :
edsdoj.f88d4cf90cfd4db19e7e750b4e9afce3
Czasopismo naukowe
Previous studies demonstrated that primo vessels (PVs) were distributed in different parts of the body in mammals, and PVs were also involved in some processes of pathology such as cancer. Whether PVs are intrinsic structures in mammals or not is still ignored. In this study, a peritonitis model rat was induced by i.p. administration of E. coli in rats. PVs were observed in all infected rats, but it appeared less in untreated rats, taking 10.53% (4/38). In addition, we examined cell types in celiac PVs by fluorescent staining with 4′,6-diamidino-2-phenylindole (DAPI) and Alexa Fluor 488 phalloidin, as well as immunofluorescent staining with CD11b and intercellular adhesion molecule-1(ICAM-1), and found the following. (1) The rod-shaped nuclei aligned longitudinally along PVs. (2) DAPI-, phalloidin-, CD11b-, and ICAM-1-positive labeling coexisted in PVs, suggesting that fibroblasts and leucocytes might be two kinds of cell types in PVs for both infected and control rats. (3) The difference was that numerous cells in PVs of the infected rats contained DAPI-labeled multilobal nucleus and were expressed with CD11b- and ICAM-1-positive labeling on the cytoplasm and membrane, showing the typical characteristics of neutrophil. (4) The cells in PVs from the untreated rats are those of loose connective tissue. Therefore, it is reasonably considered that PVs from infected rats might be the pathological products which might be involved in inflammation.

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