Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ
Tytuł pozycji:

Behavioral symptoms in mild cognitive impairment as compared with Alzheimer's disease and healthy older adults

Tytuł :
Behavioral symptoms in mild cognitive impairment as compared with Alzheimer's disease and healthy older adults
Autorzy :
VAN DER MUSSELE, Stefan
LE BASTARD, Nathalie
VERMEIREN, Yannick
SAERENS, Jos
SOMERS, Nore
MARIËN, Peter
GOEMAN, Johan
DE DEYN, Peter P
ENGELBORGHS, Sebastiaan
Pokaż więcej
Temat :
Homme
Human
Hombre
Maladie dégénérative
Degenerative disease
Enfermedad degenerativa
Pathologie de l'encéphale
Cerebral disorder
Encéfalo patología
Pathologie du système nerveux central
Central nervous system disease
Sistema nervosio central patología
Pathologie du système nerveux
Nervous system diseases
Sistema nervioso patología
Charge de l'aidant
Caregiver burden
Sobrecarga del cuidador
Déficit cognitif léger
mild cognitive impairment
Disturbio cognitivo ligero
Démence d'Alzheimer
Alzheimer disease
Demencia Alzheimer
Etude comparative
Comparative study
Estudio comparativo
Gériatrie
Geriatrics
Geriatría
Gérontologie
Gerontology
Gerontología
Individu sain
Healthy subject
Individuo sano
Lobe frontal
Frontal lobe
Lóbulo frontal
Personne âgée
Elderly
Anciano
Psychiatrie
Psychiatry
Psiquiatría
Psychologie
Psychology
Psicología
Stress
Estrés
Symptomatologie
Symptomatology
Sintomatología
Trouble cognitif
Cognitive disorder
Trastorno cognitivo
Trouble du comportement
Behavioral disorder
Trastorno conducta
Alzheimer's disease
behavioral symptoms
caregiver burden
dementia
frontal lobe symptoms
Sciences biologiques et medicales
Biological and medical sciences
Sciences medicales
Medical sciences
Generalites
General aspects
Neurologie
Neurology
Maladies dégénératives et hérédodégénératives du système nerveux. Leucodystrophies. Maladies à prions
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Psychopathologie. Psychiatrie
Psychopathology. Psychiatry
Psychologie. Psychanalyse. Psychiatrie
Psychology. Psychoanalysis. Psychiatry
PSYCHOPATHOLOGIE. PSYCHIATRIE
Cognition
Psychology, psychopathology, psychiatry
Psychologie, psychopathologie, psychiatrie
Źródło :
International journal of geriatric psychiatry. 28(3):265-275
Wydawca :
Hove: Psychology Press, 2013.
Rok publikacji :
2013
Opis fizyczny :
print; 11; 3/4 p
Materiał oryginalny :
INIST-CNRS
Typ dokumentu :
Article
Opis pliku :
text
Język :
English
Afiliacje autora :
Reference Center for Biological Markers of Dementia (BIODEM), Laboratory of Neurochemistry and Behavior, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium
Department of Nursing and Midwifery Sciences, Faculty of Medicine, University of Antwerp, Antwerp, Belgium
Department of Neurology and Memory Clinic, Hospital Network Antwerp (ZNA), Antwerp, Belgium
Department of Health Care Sciences, University College Antwerp (Artesis), Antwerp, Belgium
Department of Neurology and Alzheimer Research Center, University Medical Center Groningen, Groningen, Netherlands
ISSN :
0885-6230
Dostęp URL :
http://pascal-francis.inist.fr/vibad/index.php?action=search&terms=26852076
Prawa :
Copyright 2015 INIST-CNRS
CC BY 4.0
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Numer akcesji :
edsfra.26852076
Czasopismo naukowe
Background: Mild cognitive impairment (MCI) is a clinical concept that categorizes subjects who are in an intermediate cognitive state between normal aging and dementia. The aim of this study is to characterize behavior in MCI compared with Alzheimer's disease (AD) and healthy older patients. Design: A cross-sectional analysis of baseline data from a prospective, longitudinal study on behavioral symptoms of dementia and MCI was performed. The study population consisted of 270 MCI, 402 AD patients, and 108 healthy controls. Behavioral assessment was performed by means of Middelheim Frontality Score, Behavioral Pathology in Alzheimer's Disease Rating Scale, Cohen-Mansfield Agitation Inventory, and Cornell Scale for Depression in Dementia. Results: Moderate-to-severe behavioral symptoms were present in 13% of MCI patients, as compared with 39% in AD patients and 3% in controls (p < 0.001). The general severity of behavioral symptoms was intermediate between controls and AD patients. The three most frequent symptoms in MCI patients were aggressiveness (49%), affective disturbance (45%), and anxiety (38%); in AD patients, the most frequent symptoms were aggressiveness (60%), activity disturbances (54%), and psychosis (40%). The prevalence and severity of frontal lobe symptoms, aggressiveness, activity disturbances, and delusions was intermediate between normal aging and AD. In addition, the severity of physically non-aggressive and verbally agitated behavior and the severity of depressive symptoms were also intermediate. Conclusions: The behavioral profile of MCI patients is characterized as an intermediate state between normal aging and AD for the prevalence and severity of certain behavioral symptoms. Follow-up is ongoing to test the hypothesis that behavioral disturbances in MCI predict progression to dementia.

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies