Phosphoinositide phosphatases in a network of signalling reactions.

Szczegóły
Abstrakt

Tytuł :: Phosphoinositide phosphatases in a network of signalling reactions.
Index Terms :: Sciences bio-médicales et agricoles
Animals
Humans
Inositol 1,4,5-Trisphosphate -- genetics
Inositol 1,4,5-Trisphosphate -- metabolism
Isoenzymes -- genetics
Isoenzymes -- metabolism
PTEN Phosphohydrolase -- genetics
PTEN Phosphohydrolase -- metabolism
Phosphatidylinositols -- metabolism
Phosphoric Monoester Hydrolases -- genetics
Phosphoric Monoester Hydrolases -- physiology
Signal Transduction -- genetics
Signal Transduction -- physiology
Inositol 1,4,5-trisphosphate
Inositol polyphosphate 5-phosphatases
Myotubularin
Poly-phosphoinositides
PTEN
SHIP phosphatases
info:eu-repo/semantics/article
info:ulb-repo/semantics/articlePeerReview
info:ulb-repo/semantics/openurl/article
Wydawca :: 2007-10
Dodane szczegóły :: Blero, Daniel
Payrastre, Bernard
Schurmans, Stéphane
Erneux, Christophe
Typ dokumentu :: Zasób elektroniczny
URL :: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/52123">http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/52123
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL">http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL
Dostępność :: Open access content. Open access content
Pozostałe numery :: EQY oai:dipot.ulb.ac.be:2013/52123
uri/info:doi/10.1007/s00424-007-0304-5
uri/info:pmid/17605038
uri/info:scp/34548643512
764586835
Źródło wspomagające :: UNIV LIBR DE BRUXELLES
From OAIster®, provided by the OCLC Cooperative.
Numer akcesji :: edsoai.ocn764586835
: Zasób elektroniczny

Phosphoinositide phosphatases dephosphorylate the three positions (D-3, 4 and 5) of the inositol ring of the poly-phosphoinositides. They belong to different families of enzymes. The PtdIns(3,4)P(2) 4-phosphatase family, the tumour suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN), SAC1 domain phosphatases and myotubularins belong to the tyrosine protein phosphatases superfamily. They share the presence of a conserved cysteine residue in the consensus CX(5)RT/S. Another family consists of the inositol polyphosphate 5-phosphatase isoenzymes. The importance of these phosphoinositide phosphatases in cell regulation is illustrated by multiple examples of their implications in human diseases such as Lowe syndrome, X-linked myotubular myopathy, cancer, diabetes or bacterial infection.
Journal Article
Research Support, Non-U.S. Gov't
Review
SCOPUS: re.j
info:eu-repo/semantics/published

Informacja

Prolib Integro - strona głównaUniwersytet Ekonomiczny we Wrocławiu