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Tytuł pozycji:

Involvement of the peripheral nervous system in primary Sjogren's syndrome

Tytuł :
Involvement of the peripheral nervous system in primary Sjogren's syndrome
Index Terms :
Adult
Aged
80 and over
Female
Humans
Hypotension
Orthostatic/diagnosis/etiology
Male
Middle Aged
Neural Conduction/physiology
Peripheral Nervous System Diseases/diagnosis/*etiology
Pupil Disorders/diagnosis/etiology
Sensation Disorders/diagnosis/etiology
Sjogren's Syndrome/*complications
Statistics
Nonparametric
Temperature Sense/physiology
Valsalva Maneuver
Vibration
info:eu-repo/semantics/article
Źródło :
Annals of the Rheumatic Diseases: an international peer-reviewed journal for health professionals and researchers in the rheumatic diseases
Wydawca :
2001-01-01
Dodane szczegóły :
Barendregt, P.J. (Pieternella)
Bent, M.J. (Martin) van den
Raaij-van den Aarssen, V.J. van
Meiracker, A.H. (Anton) van den
Vecht, C.J.
Heijde, G.L. van der
Markusse, H.M.
Typ dokumentu :
Zasób elektroniczny
URL :
http://repub.eur.nl/pub/8512">http://repub.eur.nl/pub/8512
Dostępność :
Open access content. Open access content
info:eu-repo/semantics/openAccess
Pozostałe numery :
QGQ oai:repub.eur.nl:8512
urn:hdl:1765/8512
929974161
Źródło wspomagające :
ERASMUS UNIVERSITEIT ROTTERDAM
From OAIster®, provided by the OCLC Cooperative.
Numer akcesji :
edsoai.ocn929974161
Zasób elektroniczny
BACKGROUND: Involvement of the peripheral nervous system in patients with primary Sjogren's syndrome (SS) has been reported, but its prevalence in neurologically asymptomatic patients is not well known. OBJECTIVE: To assess clinical and neurophysiological features of the peripheral nervous system in patients with primary SS. PATIENTS AND METHODS: 39 (38 female) consecutive patients with primary SS, aged 20-81 years (mean 50), with a disease duration of 1-30 years (mean 8) were studied. The peripheral nervous system was evaluated by a questionnaire, physical examination, quantified sensory neurological examination, and neurophysiological measurements (nerve conduction studies). To assess autonomic cardiovascular function an orthostatic challenge test, a Valsalva manoeuvre, a forced respiration test, and pupillography were done. RESULTS: Abnormalities as indicated in the questionnaire were found in 8/39 (21%) patients, while an abnormal neurological examination was found in 7/39 (18%) patients. Abnormalities in quantified sensory neurological examination were found in 22/38 (58%) patients. In 9/39 (23%) patients, neurophysiological signs compatible with a sensory polyneuropathy were found. No differences were found in the autonomic test results, disease duration, serological parameters, or erythrocyte sedimentation rate between the patients with primary SS with and those without evidence of peripheral nervous involvement. CONCLUSION: Subclinical abnormalities of the peripheral nervous system may occur in patients with primary SS selected from a department of rheumatology, but clinically relevant involvement of the peripheral nervous system in this patient group is rare.

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