Amphetamine is a central nervous system (CNS) stimulant that releases euphoric sensations and increases mental and physical performance, overcoming fatigue. The compound imitates natural stimuli, such as food and water, that signal and allow the release of dopamine in the central nervous system. It has been previously prescribed to alleviate pain, especially in the 1960s, when American pharmaceutical companies distributed the drug widely and readily, eventually leading to widespread amphetamine abuse and the categorization of the compound as a schedule II drug in the United States. More recently, amphetamine has been used, with Food and Drug Administration (FDA) approval, to treat attention-deficit hyperactivity disorder (ADHD), narcolepsy, and obesity caused by external lifestyle factors. Non-FDA-approved uses include prescription for treatment-resistant depression.
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