Invited Perspective: PFAS Bioconcentration and Biotransformation in Early Life Stage Zebrafish and Its Implications for Human Health Protection.

The article evaluates the per- and polyfluoroalkyl substances (PFAS) bioconcentration and biotransformation in early life stage zebrafish. Topics include the study involving the rapid toxicokinetic profiling in zebrafish, the groundwork laid by the research in the integration of multiple phenotype-based toxicity end points, and the relevance and consequences of PFAS biotransformation as an additional exposure source of toxic products that can affect human health.