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Tytuł:
A new class of synthetic retinoid antibiotics effective against bacterial persisters.
Autorzy:
Kim W; Division of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA.
Zhu W; School of Engineering, Brown University, Providence, Rhode Island 02903, USA.
Hendricks GL; Division of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA.
Van Tyne D; Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA.; Department of Microbiology and Immunobiology, Harvard Medical School, Massachusetts 02115, USA.
Steele AD; Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.; Emory Antibiotic Resistance Center, Emory University, Atlanta, Georgia 30322, USA.
Keohane CE; Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.; Emory Antibiotic Resistance Center, Emory University, Atlanta, Georgia 30322, USA.
Fricke N; School of Engineering, Brown University, Providence, Rhode Island 02903, USA.
Conery AL; Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
Shen S; Division of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA.
Pan W; Division of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA.
Lee K; Division of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA.
Rajamuthiah R; Division of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA.
Fuchs BB; Division of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA.
Vlahovska PM; Department of Engineering Sciences and Applied Mathematics, Northwestern University, Evanston, Illinois 60208, USA.
Wuest WM; Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.; Emory Antibiotic Resistance Center, Emory University, Atlanta, Georgia 30322, USA.
Gilmore MS; Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA.; Department of Microbiology and Immunobiology, Harvard Medical School, Massachusetts 02115, USA.
Gao H; School of Engineering, Brown University, Providence, Rhode Island 02903, USA.
Ausubel FM; Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
Mylonakis E; Division of Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA.
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Źródło:
Nature [Nature] 2018 Apr 05; Vol. 556 (7699), pp. 103-107. Date of Electronic Publication: 2018 Mar 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Anti-Bacterial Agents/*classification
Anti-Bacterial Agents/*pharmacology
Methicillin-Resistant Staphylococcus aureus/*drug effects
Retinoids/*pharmacology
Staphylococcal Infections/*drug therapy
Staphylococcal Infections/*microbiology
Animals ; Anti-Bacterial Agents/adverse effects ; Anti-Bacterial Agents/therapeutic use ; Benzoates/chemistry ; Benzoates/pharmacology ; Benzoates/therapeutic use ; Benzoates/toxicity ; Caenorhabditis elegans/drug effects ; Caenorhabditis elegans/microbiology ; Cell Death/drug effects ; Cell Line ; Disease Models, Animal ; Drug Evaluation, Preclinical ; Drug Synergism ; Gentamicins/pharmacology ; Gentamicins/therapeutic use ; Humans ; Lipid Bilayers/chemistry ; Methicillin-Resistant Staphylococcus aureus/cytology ; Methicillin-Resistant Staphylococcus aureus/genetics ; Methicillin-Resistant Staphylococcus aureus/growth & development ; Mice ; Microbial Sensitivity Tests ; Molecular Dynamics Simulation ; Mutation ; Naphthols/chemistry ; Naphthols/pharmacology ; Naphthols/therapeutic use ; Naphthols/toxicity ; Retinoids/chemistry ; Retinoids/therapeutic use ; Retinoids/toxicity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Materials science: Share corrosion data.
Autorzy:
Li X; Key Laboratory for Corrosion and Protection of the Ministry of Education, Institute of Advanced Materials & Technology, University of Science and Technology Beijing, Beijing, China, and is at the Ningbo Institute of Material Technology & Engineering, Chinese Academy of Sciences, Ningbo, Zhejiang, China.
Zhang D
Liu Z
Li Z
Du C
Dong C
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Źródło:
Nature [Nature] 2015 Nov 26; Vol. 527 (7579), pp. 441-2.
Typ publikacji:
Journal Article
MeSH Terms:
Corrosion*
Information Dissemination*
Disasters/*prevention & control
Safety Management/*methods
Accidents/mortality ; Disasters/statistics & numerical data ; Humans ; Materials Testing
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Type-II Weyl semimetals.
Autorzy:
Soluyanov AA; Theoretische Physik and Station Q Zurich, ETH Zurich, 8093 Zurich, Switzerland.
Gresch D; Theoretische Physik and Station Q Zurich, ETH Zurich, 8093 Zurich, Switzerland.
Wang Z; Department of Physics, Princeton University, Princeton, New Jersey 08544, USA.
Wu Q; Theoretische Physik and Station Q Zurich, ETH Zurich, 8093 Zurich, Switzerland.
Troyer M; Theoretische Physik and Station Q Zurich, ETH Zurich, 8093 Zurich, Switzerland.
Dai X; Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China.
Bernevig BA; Department of Physics, Princeton University, Princeton, New Jersey 08544, USA.
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Źródło:
Nature [Nature] 2015 Nov 26; Vol. 527 (7579), pp. 495-8.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Ultrafast ultrasound localization microscopy for deep super-resolution vascular imaging.
Autorzy:
Errico C; INSERM, Institut Langevin, 1 rue Jussieu, 75005 Paris, France.; Institut Langevin, ESPCI-ParisTech, PSL Research University, 1 rue Jussieu, 75005 Paris, France.; CNRS UMR 7587, 1 rue Jussieu, 75005 Paris, France.
Pierre J; INSERM, Institut Langevin, 1 rue Jussieu, 75005 Paris, France.; Institut Langevin, ESPCI-ParisTech, PSL Research University, 1 rue Jussieu, 75005 Paris, France.; CNRS UMR 7587, 1 rue Jussieu, 75005 Paris, France.
Pezet S; CNRS, UMR 8249, 10 rue Vauquelin, 75005 Paris, France.; Brain Plasticity Unit, ESPCI-ParisTech, PSL Research University, 10 rue Vauquelin, 75005 Paris, France.
Desailly Y; INSERM, Institut Langevin, 1 rue Jussieu, 75005 Paris, France.; Institut Langevin, ESPCI-ParisTech, PSL Research University, 1 rue Jussieu, 75005 Paris, France.; CNRS UMR 7587, 1 rue Jussieu, 75005 Paris, France.
Lenkei Z; CNRS, UMR 8249, 10 rue Vauquelin, 75005 Paris, France.; Brain Plasticity Unit, ESPCI-ParisTech, PSL Research University, 10 rue Vauquelin, 75005 Paris, France.
Couture O; INSERM, Institut Langevin, 1 rue Jussieu, 75005 Paris, France.; Institut Langevin, ESPCI-ParisTech, PSL Research University, 1 rue Jussieu, 75005 Paris, France.; CNRS UMR 7587, 1 rue Jussieu, 75005 Paris, France.
Tanter M; INSERM, Institut Langevin, 1 rue Jussieu, 75005 Paris, France.; Institut Langevin, ESPCI-ParisTech, PSL Research University, 1 rue Jussieu, 75005 Paris, France.; CNRS UMR 7587, 1 rue Jussieu, 75005 Paris, France.
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Źródło:
Nature [Nature] 2015 Nov 26; Vol. 527 (7579), pp. 499-502.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microvessels*
Brain/*blood supply
Microscopy/*methods
Molecular Imaging/*methods
Ultrasonics/*methods
Animals ; Brain/cytology ; Contrast Media ; Male ; Microbubbles ; Optics and Photonics ; Rats ; Rats, Sprague-Dawley ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Extra adsorption and adsorbate superlattice formation in metal-organic frameworks.
Autorzy:
Sung Cho H; Graduate School of Energy, Environment, Water and Sustainability, WCU/BK21Plus, KAIST, Daejeon 305-701, South Korea.
Deng H; Key Laboratory of Biomedical Polymers-Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan University, Luojiashan, Wuhan 430072, China.; The Institute for Advanced Studies, Wuhan University, Wuhan 430072, China.
Miyasaka K; Graduate School of Energy, Environment, Water and Sustainability, WCU/BK21Plus, KAIST, Daejeon 305-701, South Korea.
Dong Z; Key Laboratory of Biomedical Polymers-Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan University, Luojiashan, Wuhan 430072, China.
Cho M; Graduate School of Energy, Environment, Water and Sustainability, WCU/BK21Plus, KAIST, Daejeon 305-701, South Korea.
Neimark AV; Department of Chemical and Biochemical Engineering, Rutgers University, 98 Brett Road, Piscataway, New Jersey 08854, USA.
Ku Kang J; Graduate School of Energy, Environment, Water and Sustainability, WCU/BK21Plus, KAIST, Daejeon 305-701, South Korea.
Yaghi OM; Graduate School of Energy, Environment, Water and Sustainability, WCU/BK21Plus, KAIST, Daejeon 305-701, South Korea.; Department of Chemistry, University of California, Materials Sciences Division at Lawrence Berkeley National Laboratory, and Kavli Energy NanoSciences Institute, Berkeley, California 94720, USA.; King Fahd University of Petroleum and Minerals, Dhahran 34464, Saudi Arabia.
Terasaki O; Graduate School of Energy, Environment, Water and Sustainability, WCU/BK21Plus, KAIST, Daejeon 305-701, South Korea.; Department of Materials and Environmental Chemistry, Berzelii Centre EXSELENT on Porous Materials, Stockholm University, Stockholm SE-10691, Sweden.
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Źródło:
Nature [Nature] 2015 Nov 26; Vol. 527 (7579), pp. 503-7. Date of Electronic Publication: 2015 Nov 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Drosophila Ionotropic Receptor 25a mediates circadian clock resetting by temperature.
Autorzy:
Chen C; Department of Cell and Developmental Biology, University College London, 21 University Street, London WC1E 6DE, UK.
Buhl E; School of Physiology and Pharmacology, University of Bristol, University Walk, Bristol BS8 1TD, UK.
Xu M; Department of Cell and Developmental Biology, University College London, 21 University Street, London WC1E 6DE, UK.
Croset V; Center for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, CH-1015 Lausanne, Switzerland.
Rees JS; Cambridge Centre for Proteomics, Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Tennis Court Road, Cambridge CB2 1QW, UK.
Lilley KS; Cambridge Centre for Proteomics, Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Tennis Court Road, Cambridge CB2 1QW, UK.
Benton R; Center for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, CH-1015 Lausanne, Switzerland.
Hodge JJ; School of Physiology and Pharmacology, University of Bristol, University Walk, Bristol BS8 1TD, UK.
Stanewsky R; Department of Cell and Developmental Biology, University College London, 21 University Street, London WC1E 6DE, UK.
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Źródło:
Nature [Nature] 2015 Nov 26; Vol. 527 (7579), pp. 516-20. Date of Electronic Publication: 2015 Nov 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Temperature*
Circadian Clocks/*physiology
Circadian Rhythm/*physiology
Drosophila Proteins/*metabolism
Drosophila melanogaster/*physiology
Receptors, Ionotropic Glutamate/*metabolism
Animals ; CLOCK Proteins/metabolism ; Drosophila Proteins/genetics ; Drosophila melanogaster/cytology ; Extremities/innervation ; Female ; Male ; Mechanoreceptors/cytology ; Mechanoreceptors/metabolism ; Receptors, Ionotropic Glutamate/genetics ; Sensory Receptor Cells/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Extremely metal-poor stars from the cosmic dawn in the bulge of the Milky Way.
Autorzy:
Howes LM; Research School of Astronomy and Astrophysics, Australian National University, Australian Capital Territory 2601, Australia.
Casey AR; Institute of Astronomy, University of Cambridge, Madingley Road, Cambridge CB3 0HA, UK.
Asplund M; Research School of Astronomy and Astrophysics, Australian National University, Australian Capital Territory 2601, Australia.
Keller SC; Research School of Astronomy and Astrophysics, Australian National University, Australian Capital Territory 2601, Australia.
Yong D; Research School of Astronomy and Astrophysics, Australian National University, Australian Capital Territory 2601, Australia.
Nataf DM; Research School of Astronomy and Astrophysics, Australian National University, Australian Capital Territory 2601, Australia.
Poleski R; Warsaw University Observatory, Aleje Ujazdowskie 4, 00-478 Warszawa, Poland.; Department of Astronomy, Ohio State University, 140 West 18th Avenue, Columbus, Ohio 43210, USA.
Lind K; Department of Physics and Astronomy, Division of Astronomy and Space Physics, Uppsala University, Box 516, SE-751 20 Uppsala, Sweden.
Kobayashi C; Research School of Astronomy and Astrophysics, Australian National University, Australian Capital Territory 2601, Australia.; School of Physics, Astronomy and Mathematics, Centre for Astrophysics Research, University of Hertfordshire, College Lane, Hatfield AL10 9AB, UK.
Owen CI; Research School of Astronomy and Astrophysics, Australian National University, Australian Capital Territory 2601, Australia.
Ness M; Max-Planck-Institut für Astronomie, Königstuhl 17, D-69117 Heidelberg, Germany.
Bessell MS; Research School of Astronomy and Astrophysics, Australian National University, Australian Capital Territory 2601, Australia.
Da Costa GS; Research School of Astronomy and Astrophysics, Australian National University, Australian Capital Territory 2601, Australia.
Schmidt BP; Research School of Astronomy and Astrophysics, Australian National University, Australian Capital Territory 2601, Australia.
Tisserand P; Research School of Astronomy and Astrophysics, Australian National University, Australian Capital Territory 2601, Australia.; Sorbonne Universités, UPMC Université Paris 6 et CNRS, UMR 7095, Institut d'Astrophysique de Paris, 98 bis Boulevard Arago, 75014 Paris, France.
Udalski A; Warsaw University Observatory, Aleje Ujazdowskie 4, 00-478 Warszawa, Poland.
Szymański MK; Warsaw University Observatory, Aleje Ujazdowskie 4, 00-478 Warszawa, Poland.
Soszyński I; Warsaw University Observatory, Aleje Ujazdowskie 4, 00-478 Warszawa, Poland.
Pietrzyński G; Warsaw University Observatory, Aleje Ujazdowskie 4, 00-478 Warszawa, Poland.; Universidad de Concepción, Departamento de Astronomia, Casilla 160-C, Concepción, Chile.
Ulaczyk K; Warsaw University Observatory, Aleje Ujazdowskie 4, 00-478 Warszawa, Poland.; Department of Physics, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.
Wyrzykowski Ł; Warsaw University Observatory, Aleje Ujazdowskie 4, 00-478 Warszawa, Poland.
Pietrukowicz P; Warsaw University Observatory, Aleje Ujazdowskie 4, 00-478 Warszawa, Poland.
Skowron J; Warsaw University Observatory, Aleje Ujazdowskie 4, 00-478 Warszawa, Poland.
Kozłowski S; Warsaw University Observatory, Aleje Ujazdowskie 4, 00-478 Warszawa, Poland.
Mróz P; Warsaw University Observatory, Aleje Ujazdowskie 4, 00-478 Warszawa, Poland.
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Źródło:
Nature [Nature] 2015 Nov 26; Vol. 527 (7579), pp. 484-7. Date of Electronic Publication: 2015 Nov 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance.
Autorzy:
Fischer KR; Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Department of Cell and Developmental Biology, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Neuberger Berman Lung Cancer Center, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.
Durrans A; Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Department of Cell and Developmental Biology, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Neuberger Berman Lung Cancer Center, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.
Lee S; Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Department of Cell and Developmental Biology, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Neuberger Berman Lung Cancer Center, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.
Sheng J; Department of Systems Medicine and Bioengineering, Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas 77030, USA.
Li F; Department of Systems Medicine and Bioengineering, Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas 77030, USA.
Wong ST; Department of Systems Medicine and Bioengineering, Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas 77030, USA.; Methodist Cancer Center, Houston Methodist Hospital, Houston, Texas, 77030 USA.
Choi H; Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Department of Cell and Developmental Biology, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Neuberger Berman Lung Cancer Center, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.
El Rayes T; Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Department of Cell and Developmental Biology, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Neuberger Berman Lung Cancer Center, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.
Ryu S; Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Neuberger Berman Lung Cancer Center, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Soonchunhyang Institute of Medi-bio Science (SIMS), Soonchunhyang University, 25 Bongjeong-ro Cheonan-Si, Chungcheongnam-do 31151, South Korea.
Troeger J; Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA.; Institute of Human Nutrition, Columbia University, New York, New York 10032, USA.
Schwabe RF; Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA.; Institute of Human Nutrition, Columbia University, New York, New York 10032, USA.
Vahdat LT; Department of Medicine, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.
Altorki NK; Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Neuberger Berman Lung Cancer Center, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.
Mittal V; Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Department of Cell and Developmental Biology, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Neuberger Berman Lung Cancer Center, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.
Gao D; Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Department of Cell and Developmental Biology, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.; Neuberger Berman Lung Cancer Center, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.
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Źródło:
Nature [Nature] 2015 Nov 26; Vol. 527 (7579), pp. 472-6. Date of Electronic Publication: 2015 Nov 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Drug Resistance, Neoplasm*/drug effects
Drug Resistance, Neoplasm*/genetics
Epithelial-Mesenchymal Transition*/drug effects
Epithelial-Mesenchymal Transition*/genetics
Lung Neoplasms/*pathology
Lung Neoplasms/*secondary
Mammary Neoplasms, Experimental/*drug therapy
Mammary Neoplasms, Experimental/*pathology
Neoplasm Metastasis/*pathology
Animals ; Antineoplastic Agents, Alkylating/pharmacology ; Antineoplastic Agents, Alkylating/therapeutic use ; Apoptosis/drug effects ; Cell Lineage ; Cell Proliferation/drug effects ; Cell Tracking ; Cyclophosphamide/pharmacology ; Cyclophosphamide/therapeutic use ; Disease Models, Animal ; Disease Progression ; Female ; Lung Neoplasms/drug therapy ; Lung Neoplasms/genetics ; Male ; Mammary Neoplasms, Experimental/genetics ; Mice ; MicroRNAs/genetics ; Neoplasm Metastasis/drug therapy ; Neoplasm Metastasis/genetics ; Reproducibility of Results
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Sweet and bitter taste in the brain of awake behaving animals.
Autorzy:
Peng Y; Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.; Departments of Biochemistry and Molecular Biophysics, Columbia College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.; Department of Neuroscience, Columbia College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.
Gillis-Smith S; Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.; Departments of Biochemistry and Molecular Biophysics, Columbia College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.; Department of Neuroscience, Columbia College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.
Jin H; Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.; Departments of Biochemistry and Molecular Biophysics, Columbia College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.; Department of Neuroscience, Columbia College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.
Tränkner D; Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.; Departments of Biochemistry and Molecular Biophysics, Columbia College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.; Department of Neuroscience, Columbia College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.; HHMI/Janelia Farm Research Campus, 19700 Helix Drive, Ashburn, Virginia 20147, USA.
Ryba NJ; National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA.
Zuker CS; Howard Hughes Medical Institute, Columbia College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.; Departments of Biochemistry and Molecular Biophysics, Columbia College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.; Department of Neuroscience, Columbia College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.; HHMI/Janelia Farm Research Campus, 19700 Helix Drive, Ashburn, Virginia 20147, USA.
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Źródło:
Nature [Nature] 2015 Nov 26; Vol. 527 (7579), pp. 512-5. Date of Electronic Publication: 2015 Nov 18.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Appetitive Behavior/*physiology
Avoidance Learning/*physiology
Cerebral Cortex/*cytology
Cerebral Cortex/*physiology
Taste/*physiology
Taste Perception/*physiology
Wakefulness/*physiology
Animals ; Appetitive Behavior/radiation effects ; Avoidance Learning/radiation effects ; Brain Mapping ; Cerebral Cortex/radiation effects ; Discrimination, Psychological/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Optogenetics ; Stereotaxic Techniques ; Taste Perception/radiation effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Foreign DNA capture during CRISPR-Cas adaptive immunity.
Autorzy:
Nuñez JK; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, USA.
Harrington LB; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, USA.
Kranzusch PJ; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, USA.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, California 94720, USA.
Engelman AN; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA.
Doudna JA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, USA.; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, California 94720, USA.; Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, USA.; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.; Innovative Genomics Initiative, University of California, Berkeley, Berkeley, California 94720, USA.; Center for RNA Systems Biology, University of California, Berkeley, Berkeley, California 94720, USA.
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Źródło:
Nature [Nature] 2015 Nov 26; Vol. 527 (7579), pp. 535-8. Date of Electronic Publication: 2015 Oct 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Adaptive Immunity*
Virus Integration*/genetics
Virus Integration*/immunology
CRISPR-Associated Proteins/*metabolism
Clustered Regularly Interspaced Short Palindromic Repeats/*genetics
DNA, Viral/*genetics
DNA, Viral/*immunology
Bacteriophage M13/genetics ; Bacteriophage M13/immunology ; Base Sequence ; CRISPR-Associated Proteins/chemistry ; Catalytic Domain ; Crystallography, X-Ray ; DNA, Viral/chemistry ; DNA, Viral/metabolism ; Escherichia coli/enzymology ; Escherichia coli/genetics ; Escherichia coli/immunology ; Escherichia coli/virology ; Integrases/chemistry ; Integrases/metabolism ; Models, Molecular
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Mental health: The mindful way.
Autorzy:
Louët S
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Źródło:
Nature [Nature] 2015 Nov 26; Vol. 527 (7579), pp. 553-4.
Typ publikacji:
Journal Article
MeSH Terms:
Mental Health*
Mindfulness*/education
Research Personnel/*psychology
Anxiety/prevention & control ; Anxiety/psychology ; Entrepreneurship ; Female ; Humans ; Male ; Research Personnel/education ; Stress, Psychological/prevention & control ; Stress, Psychological/psychology ; Work Performance
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Lessons from EPA on tracking pollutants.
Autorzy:
Zhang B; Information Center, Ministry of Environmental Protection, Beijing, China.
Davis WS; EPA, Washington DC, USA.
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Źródło:
Nature [Nature] 2015 Nov 26; Vol. 527 (7579), pp. 446.
Typ publikacji:
Letter
MeSH Terms:
Access to Information*
United States Environmental Protection Agency*
Environmental Pollutants/*analysis
China ; Internet/statistics & numerical data ; United States
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Collisionless encounters and the origin of the lunar inclination.
Autorzy:
Pahlevan K; Laboratoire Lagrange, Université Côte d'Azur, Observatoire de la Côte d'Azur, CNRS Boulevard de l'Observatoire CS 34229, 06304 Nice Cedex 4, France.
Morbidelli A; Laboratoire Lagrange, Université Côte d'Azur, Observatoire de la Côte d'Azur, CNRS Boulevard de l'Observatoire CS 34229, 06304 Nice Cedex 4, France.
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Źródło:
Nature [Nature] 2015 Nov 26; Vol. 527 (7579), pp. 492-4.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Hemichordate genomes and deuterostome origins.
Autorzy:
Simakov O; Molecular Genetics Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.; Department of Molecular Evolution, Centre for Organismal Studies, University of Heidelberg, 69115 Heidelberg, Germany.
Kawashima T; Marine Genomics Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.
Marlétaz F; Department of Zoology, University of Oxford, Oxford OX1 3PS, UK.
Jenkins J; HudsonAlpha Institute of Biotechnology, Huntsville, Alabama 35806, USA.
Koyanagi R; DNA Sequencing Section, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.
Mitros T; Department of Molecular and Cell Biology, University of California, Berkeley California 94720-3200, USA.
Hisata K; Marine Genomics Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.
Bredeson J; Department of Molecular and Cell Biology, University of California, Berkeley California 94720-3200, USA.
Shoguchi E; Marine Genomics Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.
Gyoja F; Marine Genomics Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.
Yue JX; Department of Ecology and Evolutionary Biology, Rice University, Houston, Texas 77005, USA.
Chen YC; Institute of Cellular and Organismic Biology, Academia Sinica, Taipei 11529, Taiwan.
Freeman RM Jr; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.
Sasaki A; Marine Biological Laboratory, Graduate School of Science, Hiroshima University, Onomichi, Hiroshima 722-0073, Japan.
Hikosaka-Katayama T; Natural Science Center for Basic Research and Development, Gene Science Division, Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8527, Japan.
Sato A; Marine Biological Association of the UK, The Laboratory, Citadel Hill, Plymouth PL1 2PB, UK.
Fujie M; DNA Sequencing Section, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.
Baughman KW; Marine Genomics Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.
Levine J; Department of Biology, Hopkins Marine Station, Stanford University, Pacific Grove, California 93950, USA.
Gonzalez P; Department of Biology, Hopkins Marine Station, Stanford University, Pacific Grove, California 93950, USA.
Cameron C; Départment de sciences biologiques, University of Montreal, Quebec H3C 3J7, Canada.
Fritzenwanker JH; Department of Biology, Hopkins Marine Station, Stanford University, Pacific Grove, California 93950, USA.
Pani AM; University of North Caroline at Chapel Hill, North Carolina 27599, USA.
Goto H; DNA Sequencing Section, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.
Kanda M; DNA Sequencing Section, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.
Arakaki N; DNA Sequencing Section, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.
Yamasaki S; DNA Sequencing Section, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.
Qu J; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Cree A; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Ding Y; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Dinh HH; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Dugan S; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Holder M; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Jhangiani SN; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Kovar CL; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Lee SL; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Lewis LR; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Morton D; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Nazareth LV; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Okwuonu G; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Santibanez J; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Chen R; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Richards S; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Muzny DM; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Gillis A; Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK.
Peshkin L; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.
Wu M; Department of Molecular and Cell Biology, University of California, Berkeley California 94720-3200, USA.
Humphreys T; Institute for Biogenesis Research, University of Hawaii, Hawaii 96822, USA.
Su YH; Institute of Cellular and Organismic Biology, Academia Sinica, Taipei 11529, Taiwan.
Putnam NH; Department of Ecology and Evolutionary Biology, Rice University, Houston, Texas 77005, USA.
Schmutz J; HudsonAlpha Institute of Biotechnology, Huntsville, Alabama 35806, USA.
Fujiyama A; National Institute of Genetics, Mishima, Shizuoka 411-8540, Japan.
Yu JK; Institute of Cellular and Organismic Biology, Academia Sinica, Taipei 11529, Taiwan.
Tagawa K; Marine Biological Laboratory, Graduate School of Science, Hiroshima University, Onomichi, Hiroshima 722-0073, Japan.
Worley KC; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Gibbs RA; Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, MS BCM226, Houston, Texas 77030, USA.
Kirschner MW; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.
Lowe CJ; Department of Biology, Hopkins Marine Station, Stanford University, Pacific Grove, California 93950, USA.
Satoh N; Marine Genomics Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.
Rokhsar DS; Molecular Genetics Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.; Department of Molecular and Cell Biology, University of California, Berkeley California 94720-3200, USA.; US Department of Energy Joint Genome Institute, Walnut Creek, California 94598, USA.
Gerhart J; Department of Molecular and Cell Biology, University of California, Berkeley California 94720-3200, USA.
Pokaż więcej
Źródło:
Nature [Nature] 2015 Nov 26; Vol. 527 (7579), pp. 459-65. Date of Electronic Publication: 2015 Nov 18.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Evolution, Molecular*
Chordata, Nonvertebrate/*genetics
Genome/*genetics
Animals ; Chordata, Nonvertebrate/classification ; Conserved Sequence/genetics ; Echinodermata/classification ; Echinodermata/genetics ; Multigene Family/genetics ; Phylogeny ; Signal Transduction ; Synteny/genetics ; Transforming Growth Factor beta
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-25 z 28960

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