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Tytuł:
Y-box binding protein 1 in small extracellular vesicles reduces mesenchymal stem cell differentiation to osteoblasts-implications for acute myeloid leukaemia.
Autorzy:
Chetty VK; Department of Pediatrics III, University Hospital Essen, Essen, Germany.
Ghanam J; Department of Pediatrics III, University Hospital Essen, Essen, Germany.
Lichá K; Department of Pediatrics III, University Hospital Essen, Essen, Germany.; Institute of Molecular Biomedicine, Faculty of Medicine, Comenius University in Bratislava, Bratislava, Slovakia.
Brenzel A; Imaging Center Essen (IMCES), University Hospital Essen, Essen, Germany.
Reinhardt D; Department of Pediatrics III, University Hospital Essen, Essen, Germany.
Thakur BK; Department of Pediatrics III, University Hospital Essen, Essen, Germany.; European Liquid Biopsy Society, Hamburg, Germany.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Mar; Vol. 13 (3), pp. e12417.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Vesicles*/metabolism
Leukemia, Myeloid, Acute*
Mesenchymal Stem Cells*/metabolism
Child ; Humans ; Chromatography, Liquid ; Osteoblasts ; Osteogenesis ; Tandem Mass Spectrometry ; Tumor Microenvironment ; Y-Box-Binding Protein 1/metabolism
Czasopismo naukowe
Tytuł:
Endothelial cell-derived extracellular vesicles expressing surface VCAM1 promote sepsis-related acute lung injury by targeting and reprogramming monocytes.
Autorzy:
Wang L; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Tang Y; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Tang J; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Liu X; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Zi S; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Li S; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Chen H; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Liu A; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Huang W; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Xie J; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Liu L; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Chao J; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.; Department of Physiology, School of Medicine, Southeast University, Nanjing, China.
Qiu H; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Mar; Vol. 13 (3), pp. e12423.
Typ publikacji:
Journal Article
MeSH Terms:
Acute Lung Injury*/metabolism
Extracellular Vesicles*/metabolism
Monocytes*/metabolism
Sepsis*/complications
Sepsis*/metabolism
Vascular Cell Adhesion Molecule-1*/metabolism
Humans ; Endothelial Cells/metabolism ; Respiratory Distress Syndrome/metabolism
Czasopismo naukowe
Tytuł:
Proteomic analysis of ascitic extracellular vesicles describes tumour microenvironment and predicts patient survival in ovarian cancer.
Autorzy:
Vyhlídalová Kotrbová A; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.
Gömöryová K; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.
Mikulová A; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.
Plešingerová H; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.
Sladeček S; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.
Kravec M; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.
Hrachovinová Š; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.
Potěšil D; Central European Institute of Technology, Masaryk University, Brno, Czech Republic.
Dunsmore G; Institut Gustave Roussy, INSERM U1015, Villejuif, France.
Blériot C; Institut Gustave Roussy, INSERM U1015, Villejuif, France.; Institut Necker Enfants Malades, IMMEDIAB, Paris, France.
Bied M; Institut Gustave Roussy, INSERM U1015, Villejuif, France.
Kotouček J; Department of Pharmacology and Toxicology, Veterinary Research Institute, Brno, Czech Republic.
Bednaříková M; Department of Internal Medicine - Hematology & Oncology, University Hospital Brno and Medical Faculty, Masaryk University, Brno, Czech Republic.
Hausnerová J; Department of Pathology, University Hospital Brno and Medical Faculty, Masaryk University, Brno, Czech Republic.
Minář L; Department of Obstetrics and Gynecology, University Hospital Brno and Medical Faculty, Masaryk University, Brno, Czech Republic.
Crha I; Department of Health Sciences, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Felsinger M; Department of Obstetrics and Gynecology, University Hospital Brno and Medical Faculty, Masaryk University, Brno, Czech Republic.
Zdráhal Z; Central European Institute of Technology, Masaryk University, Brno, Czech Republic.
Ginhoux F; Institut Gustave Roussy, INSERM U1015, Villejuif, France.
Weinberger V; Department of Obstetrics and Gynecology, University Hospital Brno and Medical Faculty, Masaryk University, Brno, Czech Republic.
Bryja V; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.
Pospíchalová V; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Mar; Vol. 13 (3), pp. e12420.
Typ publikacji:
Journal Article
MeSH Terms:
Cystadenocarcinoma, Serous*/diagnosis
Cystadenocarcinoma, Serous*/genetics
Cystadenocarcinoma, Serous*/metabolism
Extracellular Vesicles*/metabolism
Ovarian Neoplasms*/diagnosis
Humans ; Female ; Ascites/metabolism ; Ascites/pathology ; Tumor Microenvironment ; Proteomics
Czasopismo naukowe
Tytuł:
PD-L1 on large extracellular vesicles is a predictive biomarker for therapy response in tissue PD-L1-low and -negative patients with non-small cell lung cancer.
Autorzy:
Schöne N; University of Münster, Department of Medicine A, Hematology, Oncology, and Pneumology, Münster, Germany.; University Hospital Münster, West German Cancer Center, Münster, Germany.
Kemper M; University of Münster, Department of Medicine A, Hematology, Oncology, and Pneumology, Münster, Germany.; University Hospital Münster, West German Cancer Center, Münster, Germany.
Menck K; University of Münster, Department of Medicine A, Hematology, Oncology, and Pneumology, Münster, Germany.; University Hospital Münster, West German Cancer Center, Münster, Germany.
Evers G; University of Münster, Department of Medicine A, Hematology, Oncology, and Pneumology, Münster, Germany.; University Hospital Münster, West German Cancer Center, Münster, Germany.
Krekeler C; University of Münster, Department of Medicine A, Hematology, Oncology, and Pneumology, Münster, Germany.; University Hospital Münster, West German Cancer Center, Münster, Germany.
Schulze AB; University of Münster, Department of Medicine A, Hematology, Oncology, and Pneumology, Münster, Germany.; University Hospital Münster, West German Cancer Center, Münster, Germany.
Lenz G; University of Münster, Department of Medicine A, Hematology, Oncology, and Pneumology, Münster, Germany.
Wardelmann E; University of Münster, Gerhard-Domagk-Institute of Pathology, Münster, Germany.
Binder C; University Medicine Göttingen, Clinic for Hematology/Medical Oncology, Göttingen, Germany.
Bleckmann A; University of Münster, Department of Medicine A, Hematology, Oncology, and Pneumology, Münster, Germany.; University Hospital Münster, West German Cancer Center, Münster, Germany.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Mar; Vol. 13 (3), pp. e12418.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/therapy
Lung Neoplasms*/therapy
Lung Neoplasms*/metabolism
Extracellular Vesicles*/metabolism
Humans ; B7-H1 Antigen ; Biomarkers
Czasopismo naukowe
Tytuł:
Extracellular vesicles as a promising source of lipid biomarkers for breast cancer detection in blood plasma.
Autorzy:
Dorado E; Faculty of Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
Doria ML; Faculty of Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
Nagelkerke A; Faculty of Engineering, Department of Bioengineering, Department of Materials, Institute of Biomedical Engineering, Imperial College London, London, United Kingdom.
McKenzie JS; Faculty of Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
Maneta-Stavrakaki S; Faculty of Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
Whittaker TE; Faculty of Engineering, Department of Bioengineering, Department of Materials, Institute of Biomedical Engineering, Imperial College London, London, United Kingdom.
Nicholson JK; Institute of Global Health Innovation, Imperial College London, London, United Kingdom.
Coombes RC; Faculty of Medicine, Department of Surgery and Cancer, Imperial College London, London, United Kingdom.
Stevens MM; Faculty of Engineering, Department of Bioengineering, Department of Materials, Institute of Biomedical Engineering, Imperial College London, London, United Kingdom.
Takats Z; Faculty of Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.; PRISM Inserm U1192, University of Lille, Lille, France.; Deparment of Immunomedicine, University of Regensburg, Regensburg, Germany.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Mar; Vol. 13 (3), pp. e12419.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Vesicles*
Breast Neoplasms*/diagnosis
Humans ; Female ; Plasma ; Biomarkers ; Glycerophospholipids
Czasopismo naukowe
Tytuł:
MISEV2023: An updated guide to EV research and applications.
Autorzy:
Welsh JA; Translational Nanobiology Section, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Goberdhan DC; Nuffield Department of Women's and Reproductive Health, University of Oxford, Women's Centre, John Radcliffe Hospital, Oxford, UK.
O'Driscoll L; School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland.; Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.; Trinity St. James's Cancer Institute, Trinity College Dublin, Dublin, Ireland.
Théry C; Institut Curie, INSERM U932, PSL University, Paris, France.; CurieCoreTech Extracellular Vesicles, Institut Curie, Paris, France.
Witwer KW; Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; EV Core Facility 'EXCEL', Institute for Basic Biomedical Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; The Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Feb; Vol. 13 (2), pp. e12416.
Typ publikacji:
Editorial
Opinia redakcyjna
Tytuł:
Lipid profile of circulating placental extracellular vesicles during pregnancy identifies foetal growth restriction risk.
Autorzy:
Klemetti MM; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Obstetrics & Gynecology, University of Toronto, Toronto, Ontario, Canada.
Pettersson ABV; Program in Translational Medicine, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Ontario, Canada.
Ahmad Khan A; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Canada.
Ermini L; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
Porter TR; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
Litvack ML; Program in Translational Medicine, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Ontario, Canada.
Alahari S; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
Zamudio S; Placental Research Group LLC, Maplewood, New Jersey, USA.
Illsley NP; Placental Research Group LLC, Maplewood, New Jersey, USA.
Röst H; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Canada.
Post M; Program in Translational Medicine, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Ontario, Canada.; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.; Department Physiology, University of Toronto, Toronto, Ontario, Canada.
Caniggia I; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Obstetrics & Gynecology, University of Toronto, Toronto, Ontario, Canada.; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.; Department Physiology, University of Toronto, Toronto, Ontario, Canada.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Feb; Vol. 13 (2), pp. e12413.
Typ publikacji:
Journal Article
MeSH Terms:
Fetal Growth Retardation*/diagnosis
Extracellular Vesicles*
Infant, Newborn ; Pregnancy ; Female ; Humans ; Placenta ; Tandem Mass Spectrometry ; Lipids
Czasopismo naukowe
Tytuł:
Bioengineered small extracellular vesicles deliver multiple SARS-CoV-2 antigenic fragments and drive a broad immunological response.
Autorzy:
Jackson HK; Department of Pathology, University of Cambridge, Cambridge, UK.; Exosis, Inc. Palm Beach, Palm Beach, Florida, USA.
Long HM; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
Yam-Puc JC; MRC Toxicology Unit, University of Cambridge, Cambridge, UK.
Palmulli R; Department of Pathology, University of Cambridge, Cambridge, UK.
Haigh TA; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
Gerber PP; Cambridge Institute of Therapeutic Immunology and Infectious Disease (CITIID), University of Cambridge, Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.
Lee JS; Department of Pathology, University of Cambridge, Cambridge, UK.
Matheson NJ; Cambridge Institute of Therapeutic Immunology and Infectious Disease (CITIID), University of Cambridge, Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant, Cambridge, UK.
Young L; Exosis, Inc. Palm Beach, Palm Beach, Florida, USA.
Trowsdale J; Exosis, Inc. Palm Beach, Palm Beach, Florida, USA.
Lo M; Exosis, Inc. Palm Beach, Palm Beach, Florida, USA.
Taylor GS; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
Thaventhiran JE; MRC Toxicology Unit, University of Cambridge, Cambridge, UK.
Edgar JR; Department of Pathology, University of Cambridge, Cambridge, UK.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Feb; Vol. 13 (2), pp. e12412.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*
Extracellular Vesicles*
Vaccines*
Animals ; Humans ; Mice ; SARS-CoV-2 ; Pandemics
Czasopismo naukowe
Tytuł:
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches.
Autorzy:
Welsh JA; Translational Nanobiology Section, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Goberdhan DCI; Nuffield Department of Women's and Reproductive Health, University of Oxford, Women's Centre, John Radcliffe Hospital, Oxford, UK.
O'Driscoll L; School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland.; Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.; Trinity St. James's Cancer Institute, Trinity College Dublin, Dublin, Ireland.
Buzas EI; Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary.; HCEMM-SU Extracellular Vesicle Research Group, Semmelweis University, Budapest, Hungary.; HUN-REN-SU Translational Extracellular Vesicle Research Group, Semmelweis University, Budapest, Hungary.
Blenkiron C; Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Bussolati B; Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.
Cai H; University of Georgia, Athens, Georgia, USA.
Di Vizio D; Department of Surgery, Division of Cancer Biology and Therapeutics, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Driedonks TAP; Department CDL Research, University Medical Center Utrecht, Utrecht, The Netherlands.
Erdbrügger U; University of Virginia Health System, Charlottesville, Virginia, USA.
Falcon-Perez JM; Exosomes Laboratory, Center for Cooperative Research in Biosciences, Basque Research and Technology Alliance, Derio, Spain.; Metabolomics Platform, Center for Cooperative Research in Biosciences, Basque Research and Technology Alliance, Derio, Spain.; IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.
Fu QL; Otorhinolaryngology Hospital, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Extracellular Vesicle Research and Clinical Translational Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Hill AF; Institute for Health and Sport, Victoria University, Melbourne, Australia.
Lenassi M; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Lim SK; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Paracrine Therapeutics Pte. Ltd., Singapore, Singapore.; Department of Surgery, YLL School of Medicine, National University Singapore, Singapore, Singapore.
Mahoney MG; Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Mohanty S; Stem Cell Facility, All India Institute of Medical Sciences, New Delhi, India.
Möller A; Chinese University of Hong Kong, Hong Kong, Hong Kong S.A.R.; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Nieuwland R; Laboratory of Experimental Clinical Chemistry, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Vesicle Center, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.
Ochiya T; Tokyo Medical University, Tokyo, Japan.
Sahoo S; Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Torrecilhas AC; Laboratório de Imunologia Celular e Bioquímica de Fungos e Protozoários, Departamento de Ciências Farmacêuticas, Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo (UNIFESP) Campus Diadema, Diadema, Brazil.
Zheng L; Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zijlstra A; Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Genentech, South San Francisco, California, USA.
Abuelreich S; Department of Molecular Medicine, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, California, USA.
Bagabas R; Department of Molecular Medicine, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, California, USA.
Bergese P; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.; Center for Colloid and Surface Science (CSGI), Florence, Italy.; National Center for Gene Therapy and Drugs based on RNA Technology, Padua, Italy.
Bridges EM; Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Brucale M; Consiglio Nazionale delle Ricerche - Istituto per lo Studio dei Materiali Nanostrutturati, Bologna, Italy.; Consorzio Interuniversitario per lo Sviluppo dei Sistemi a Grande Interfase, Florence, Italy.
Burger D; Kidney Research Centre, Ottawa Hopsital Research Institute, Ottawa, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Canada.; School of Pharmaceutical Sciences, University of Ottawa, Ottawa, Canada.
Carney RP; Department of Biomedical Engineering, University of California, Davis, California, USA.
Cocucci E; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.; Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.
Crescitelli R; Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Hanser E; Department of Biomedicine, University Hospital Basel, Basel, Switzerland.; Department of Biomedicine, University of Basel, Basel, Switzerland.
Harris AL; Department of Oncology, University of Oxford, Oxford, UK.
Haughey NJ; Departments of Neurology and Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Hendrix A; Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent, Ghent, Belgium.
Ivanov AR; Barnett Institute of Chemical and Biological Analysis, Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, USA.
Jovanovic-Talisman T; Department of Cancer Biology and Molecular Medicine, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, California, USA.
Kruh-Garcia NA; Bio-pharmaceutical Manufacturing and Academic Resource Center (BioMARC), Infectious Disease Research Center, Colorado State University, Fort Collins, Colorado, USA.
Ku'ulei-Lyn Faustino V; Department of Molecular Medicine, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, California, USA.
Kyburz D; Department of Biomedicine, University of Basel, Basel, Switzerland.; Department of Rheumatology, University Hospital Basel, Basel, Switzerland.
Lässer C; Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Lennon KM; Department of Molecular Medicine, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, California, USA.
Lötvall J; Krefting Research Centre, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Maddox AL; Department of Molecular Medicine, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, California, USA.
Martens-Uzunova ES; Erasmus MC Cancer Institute, University Medical Center Rotterdam, Department of Urology, Rotterdam, The Netherlands.
Mizenko RR; Department of Biomedical Engineering, University of California, Davis, California, USA.
Newman LA; College of Medicine and Public Health, Flinders University, Adelaide, Australia.
Ridolfi A; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Rohde E; Department of Transfusion Medicine, University Hospital, Salzburger Landeskliniken GmbH of Paracelsus Medical University, Salzburg, Austria.; GMP Unit, Paracelsus Medical University, Salzburg, Austria.; Transfer Centre for Extracellular Vesicle Theralytic Technologies, EV-TT, Salzburg, Austria.
Rojalin T; Department of Biomedical Engineering, University of California, Davis, California, USA.; Expansion Therapeutics, Structural Biology and Biophysics, Jupiter, Florida, USA.
Rowland A; College of Medicine and Public Health, Flinders University, Adelaide, Australia.
Saftics A; Department of Molecular Medicine, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, California, USA.
Sandau US; Department of Anesthesiology & Perioperative Medicine, Oregon Health & Science University, Portland, Oregon, USA.
Saugstad JA; Department of Anesthesiology & Perioperative Medicine, Oregon Health & Science University, Portland, Oregon, USA.
Shekari F; Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.; Celer Diagnostics, Toronto, Canada.
Swift S; Waipapa Taumata Rau University of Auckland, Auckland, New Zealand.
Ter-Ovanesyan D; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts, USA.
Tosar JP; Universidad de la República, Montevideo, Uruguay.; Institut Pasteur de Montevideo, Montevideo, Uruguay.
Useckaite Z; College of Medicine and Public Health, Flinders University, Adelaide, Australia.
Valle F; Consiglio Nazionale delle Ricerche - Istituto per lo Studio dei Materiali Nanostrutturati, Bologna, Italy.; Consorzio Interuniversitario per lo Sviluppo dei Sistemi a Grande Interfase, Florence, Italy.
Varga Z; Biological Nanochemistry Research Group, Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Budapest, Hungary.; Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary.
van der Pol E; Amsterdam Vesicle Center, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Biomedical Engineering and Physics, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands.; Laboratory of Experimental Clinical Chemistry, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands.
van Herwijnen MJC; Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Wauben MHM; Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Wehman AM; University of Denver, Denver, USA.
Williams S; International Society for Extracellular Vesicles.
Zendrini A; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.; Center for Colloid and Surface Science (CSGI), Florence, Italy.
Zimmerman AJ; Barnett Institute of Chemical and Biological Analysis, Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, USA.
Théry C; Institut Curie, INSERM U932, PSL University, Paris, France.; CurieCoreTech Extracellular Vesicles, Institut Curie, Paris, France.
Witwer KW; Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; EV Core Facility 'EXCEL', Institute for Basic Biomedical Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; The Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
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Corporate Authors:
MISEV Consortium
Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Feb; Vol. 13 (2), pp. e12404.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Vesicles*/metabolism
Exosomes*/metabolism
Biological Transport ; Biomarkers/metabolism ; Phenotype
Czasopismo naukowe
Tytuł:
Identification of specific markers for human pluripotent stem cell-derived small extracellular vesicles.
Autorzy:
Chen Z; Institute of Microsurgery on Extremities, Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Luo L; Institute of Microsurgery on Extremities, Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Ye T; Institute of Microsurgery on Extremities, Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhou J; Institute of Microsurgery on Extremities, Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Niu X; Institute of Microsurgery on Extremities, Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuan J; Institute of Microsurgery on Extremities, Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuan T; Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Fu D; Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li H; School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.; Chemical and Environmental Engineering Department, School of Engineering, RMIT University, Melbourne, Victoria, Australia.
Li Q; Institute of Microsurgery on Extremities, Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wang Y; Institute of Microsurgery on Extremities, Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Feb; Vol. 13 (2), pp. e12409.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Vesicles*
Pluripotent Stem Cells*/metabolism
Humans ; Proteomics ; Chromatography, Liquid ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł:
Transfer of inflammatory mitochondria via extracellular vesicles from M1 macrophages induces ferroptosis of pancreatic beta cells in acute pancreatitis.
Autorzy:
Gao Y; Precision Medicine Laboratory for Chronic Non-communicable Diseases of Shandong Province, Institute of Precision Medicine, Jining Medical University, Jining, Shandong, China.; Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Mi N; College of Animal Science and Technology, College of Veterinary Medicine, Zhejiang A&F University, Lin'an, China.
Wu W; Precision Medicine Laboratory for Chronic Non-communicable Diseases of Shandong Province, Institute of Precision Medicine, Jining Medical University, Jining, Shandong, China.
Zhao Y; Precision Medicine Laboratory for Chronic Non-communicable Diseases of Shandong Province, Institute of Precision Medicine, Jining Medical University, Jining, Shandong, China.
Fan F; Precision Medicine Laboratory for Chronic Non-communicable Diseases of Shandong Province, Institute of Precision Medicine, Jining Medical University, Jining, Shandong, China.
Liao W; Precision Medicine Laboratory for Chronic Non-communicable Diseases of Shandong Province, Institute of Precision Medicine, Jining Medical University, Jining, Shandong, China.
Ming Y; Precision Medicine Laboratory for Chronic Non-communicable Diseases of Shandong Province, Institute of Precision Medicine, Jining Medical University, Jining, Shandong, China.
Guan W; College of Animal Science and Technology, College of Veterinary Medicine, Zhejiang A&F University, Lin'an, China.
Bai C; Precision Medicine Laboratory for Chronic Non-communicable Diseases of Shandong Province, Institute of Precision Medicine, Jining Medical University, Jining, Shandong, China.; Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Feb; Vol. 13 (2), pp. e12410.
Typ publikacji:
Journal Article
MeSH Terms:
Ferroptosis*
Insulin-Secreting Cells*/metabolism
Pancreatitis*/metabolism
Extracellular Vesicles*/metabolism
Humans ; Acute Disease ; Macrophages/metabolism ; Mitochondria
Czasopismo naukowe
Tytuł:
Tumour tissue-derived small extracellular vesicles reflect molecular subtypes of bladder cancer.
Autorzy:
Dong L; Department of Urology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; The Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Feng M; The Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Kuczler MD; The Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Horie K; The Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Urology, Gifu University Graduate School of Medicine, Gifu, Japan.
Kim CJ; The Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Ma Z; Department of Urology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lombardo K; The Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Lyons H; The Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Amend SR; The Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Kates M; The Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Bivalacqua TJ; Division of Urology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
McConkey D; The Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Xue W; Department of Urology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Choi W; The Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Pienta KJ; The Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Feb; Vol. 13 (2), pp. e12402.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Vesicles*/genetics
Urinary Bladder Neoplasms*/genetics
Urinary Bladder Neoplasms*/pathology
Humans ; Urinary Bladder ; Biomarkers, Tumor/genetics ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł:
Heat inactivation of foetal bovine serum performed after EV-depletion influences the proteome of cell-derived extracellular vesicles.
Autorzy:
Urzì O; Sahlgrenska Center for Cancer Research and Wallenberg Centre for Molecular and Translational Medicine, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Biomedicine, Neurosciences and Advanced Diagnostics (Bi.N.D), University of Palermo, Palermo, Italy.
Bergqvist M; Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Lässer C; Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Moschetti M; Sahlgrenska Center for Cancer Research and Wallenberg Centre for Molecular and Translational Medicine, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Biomedicine, Neurosciences and Advanced Diagnostics (Bi.N.D), University of Palermo, Palermo, Italy.
Johansson J; Sahlgrenska Center for Cancer Research and Wallenberg Centre for Molecular and Translational Medicine, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Surgery, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.
D Arrigo D; Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Regenerative Medicine Technologies Laboratory, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Olofsson Bagge R; Sahlgrenska Center for Cancer Research and Wallenberg Centre for Molecular and Translational Medicine, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Surgery, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.
Crescitelli R; Sahlgrenska Center for Cancer Research and Wallenberg Centre for Molecular and Translational Medicine, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Jan; Vol. 13 (1), pp. e12408.
Typ publikacji:
Journal Article
MeSH Terms:
Proteome*
Extracellular Vesicles*
Humans ; Serum Albumin, Bovine ; Hot Temperature ; Cell Culture Techniques
Czasopismo naukowe
Tytuł:
Extracellular vesicles from periodontal pathogens regulate hepatic steatosis via Toll-like receptor 2 and plasminogen activator inhibitor-1.
Autorzy:
Kim HY; Department of Oral Microbiology and Immunology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.; Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Lim Y; Department of Oral Microbiology and Immunology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Jang JS; Department of Cell and Developmental Biology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Ko YK; Department of Immunology and Molecular Microbiology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Choi Y; Department of Immunology and Molecular Microbiology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.; Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Kim HH; Department of Cell and Developmental Biology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.; Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Choi BK; Department of Oral Microbiology and Immunology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Jan; Vol. 13 (1), pp. e12407.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Vesicles*
Non-alcoholic Fatty Liver Disease*
Plasminogen Activator Inhibitor 1*
Toll-Like Receptor 2*
Animals ; Humans ; Mice
Czasopismo naukowe
Tytuł:
Differential temporal release and lipoprotein loading in B. thetaiotaomicron bacterial extracellular vesicles.
Autorzy:
Juodeikis R; Food, Microbiome, and Health Research Programme, Quadram Institute Bioscience, Norwich, UK.
Martins C; Proteomics Facility, John Innes Centre, Norwich, UK.
Saalbach G; Proteomics Facility, John Innes Centre, Norwich, UK.
Richardson J; Proteomics Facility, John Innes Centre, Norwich, UK.
Koev T; Food, Microbiome, and Health Research Programme, Quadram Institute Bioscience, Norwich, UK.; School of Pharmacy, University of East Anglia, Norwich, UK.
Baker DJ; Food, Microbiome, and Health Research Programme, Quadram Institute Bioscience, Norwich, UK.
Defernez M; Food, Microbiome, and Health Research Programme, Quadram Institute Bioscience, Norwich, UK.
Warren M; Food, Microbiome, and Health Research Programme, Quadram Institute Bioscience, Norwich, UK.; School of Biosciences, University of Kent, Canterbury, UK.; School of Biological Sciences, University of East Anglia, Norwich, UK.
Carding SR; Food, Microbiome, and Health Research Programme, Quadram Institute Bioscience, Norwich, UK.; Norwich Medical School, University of East Anglia, Norwich, UK.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Jan; Vol. 13 (1), pp. e12406.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Vesicles*/metabolism
Bacteroides thetaiotaomicron*
Lipoproteins/analysis
Czasopismo naukowe
Tytuł:
Extracellular vesicle-mediated delivery of CRISPR/Cas9 ribonucleoprotein complex targeting proprotein convertase subtilisin-kexin type 9 (Pcsk9) in primary mouse hepatocytes.
Autorzy:
Ilahibaks NF; Laboratory of Experimental Cardiology, Department Heart & Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.
Kluiver TA; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
de Jong OG; Department of Pharmaceutics, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherland.
de Jager SCA; Laboratory of Experimental Cardiology, Department Heart & Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.
Schiffelers RM; CDL Research, University Medical Center Utrecht, Utrecht, The Netherlands.
Vader P; Laboratory of Experimental Cardiology, Department Heart & Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.; CDL Research, University Medical Center Utrecht, Utrecht, The Netherlands.
Peng WC; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Lei Z; Laboratory of Experimental Cardiology, Department Heart & Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.; CDL Research, University Medical Center Utrecht, Utrecht, The Netherlands.
Sluijter JPG; Laboratory of Experimental Cardiology, Department Heart & Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.; Circulatory Health Laboratory, Regenerative Medicine Center, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.
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Źródło:
Journal of extracellular vesicles [J Extracell Vesicles] 2024 Jan; Vol. 13 (1), pp. e12389.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Vesicles*
Animals ; Mice ; Cholesterol, LDL ; CRISPR-Cas Systems ; Hepatocytes ; Proprotein Convertase 9/genetics ; Subtilisins ; Tacrolimus Binding Protein 1A
Czasopismo naukowe

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