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Tytuł :
Histamine H1 receptor deletion in cholinergic neurons induces sensorimotor gating ability deficit and social impairments in mice.
Autorzy :
Cheng, Li
Xu, Cenglin
Wang, Lu
An, Dadao
Jiang, Lei
Zheng, Yanrong
Xu, Yixin
Wang, Yi
Wang, Yujing
Zhang, Kuo
Wang, Xiaodong
Zhang, Xiangnan
Bao, Aimin
Zhou, Yudong
Yang, Jingyu
Duan, Shumin
Swaab, Dick F.
Hu, Weiwei
Chen, Zhong
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Temat :
CHOLINERGIC receptors
HISTAMINE receptors
SOCIAL skills
NEURONS
PREFRONTAL cortex
MUSCARINIC receptors
Źródło :
Nature Communications; 2/18/2021, Vol. 12 Issue 1, p1-17, 17p
Czasopismo naukowe
Tytuł :
BDNF haploinsufficiency induces behavioral endophenotypes of schizophrenia in male mice that are rescued by enriched environment.
Autorzy :
Harb M; Institute for Pharmacology and Toxicology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Jagusch J; Institute for Pharmacology and Toxicology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Durairaja A; Institute for Pharmacology and Toxicology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Endres T; Institute of Physiology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Leßmann V; Institute of Physiology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany. .; Center for Behavioral Brain Sciences, Otto-von-Guericke University Magdeburg, Magdeburg, Germany. .
Fendt M; Institute for Pharmacology and Toxicology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany. .; Center for Behavioral Brain Sciences, Otto-von-Guericke University Magdeburg, Magdeburg, Germany. .
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Źródło :
Translational psychiatry [Transl Psychiatry] 2021 Apr 22; Vol. 11 (1), pp. 233. Date of Electronic Publication: 2021 Apr 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The epistatic interaction between the dopamine D3 receptor and dysbindin-1 modulates higher-order cognitive functions in mice and humans.
Autorzy :
Leggio GM; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy. .
Torrisi SA; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Mastrogiacomo R; Department of Neuroscience and Brain Technologies, Genetics of Cognition laboratory, Istituto Italiano di Tecnologia, via Morego, 30, 16163, Genova, Italy.
Mauro D; Department of Neuroscience and Brain Technologies, Genetics of Cognition laboratory, Istituto Italiano di Tecnologia, via Morego, 30, 16163, Genova, Italy.
Chisari M; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Devroye C; Department of Neuroscience and Brain Technologies, Genetics of Cognition laboratory, Istituto Italiano di Tecnologia, via Morego, 30, 16163, Genova, Italy.
Scheggia D; Department of Neuroscience and Brain Technologies, Genetics of Cognition laboratory, Istituto Italiano di Tecnologia, via Morego, 30, 16163, Genova, Italy.
Nigro M; Department of Neuroscience and Brain Technologies, Genetics of Cognition laboratory, Istituto Italiano di Tecnologia, via Morego, 30, 16163, Genova, Italy.
Geraci F; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Pintori N; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
Giurdanella G; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Costa L; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Bucolo C; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Ferretti V; Department of Neuroscience and Brain Technologies, Genetics of Cognition laboratory, Istituto Italiano di Tecnologia, via Morego, 30, 16163, Genova, Italy.
Sortino MA; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Ciranna L; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
De Luca MA; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Mereu M; Department of Neuroscience and Brain Technologies, Genetics of Cognition laboratory, Istituto Italiano di Tecnologia, via Morego, 30, 16163, Genova, Italy.
Managò F; Department of Neuroscience and Brain Technologies, Genetics of Cognition laboratory, Istituto Italiano di Tecnologia, via Morego, 30, 16163, Genova, Italy.
Salomone S; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Drago F; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Papaleo F; Department of Neuroscience and Brain Technologies, Genetics of Cognition laboratory, Istituto Italiano di Tecnologia, via Morego, 30, 16163, Genova, Italy. .
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Źródło :
Molecular psychiatry [Mol Psychiatry] 2021 Apr; Vol. 26 (4), pp. 1272-1285. Date of Electronic Publication: 2019 Sep 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Histamine H 1 receptor deletion in cholinergic neurons induces sensorimotor gating ability deficit and social impairments in mice.
Autorzy :
Cheng L; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.; Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, P.R. China.
Xu C; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.; Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, P.R. China.
Wang L; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
An D; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Jiang L; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Zheng Y; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Xu Y; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Wang Y; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.; Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, P.R. China.
Wang Y; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Zhang K; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, P.R. China.
Wang X; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Zhang X; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Bao A; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Zhou Y; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Yang J; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, P.R. China.
Duan S; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China.
Swaab DF; Netherlands Institute for Neuroscience, an Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, BA, the Netherlands.
Hu W; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China. .
Chen Z; Institute of Pharmacology & Toxicology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, School of Basic Medical Sciences, Zhejiang University, Hangzhou, Zhejiang, P.R. China. .; Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, P.R. China. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 18; Vol. 12 (1), pp. 1142. Date of Electronic Publication: 2021 Feb 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Sensory Gating*
Social Behavior*
Cholinergic Neurons/*metabolism
Receptors, Histamine H1/*metabolism
Anhedonia/drug effects ; Animals ; Behavior, Animal/drug effects ; Choline O-Acetyltransferase/metabolism ; Cognitive Dysfunction/complications ; Dizocilpine Maleate/pharmacology ; Female ; Integrases/metabolism ; Locomotion/drug effects ; Male ; Mice ; Mice, Transgenic ; Prefrontal Cortex/drug effects ; Prefrontal Cortex/pathology ; Schizophrenia/pathology
Czasopismo naukowe
Tytuł :
Impaired Sensorimotor Gating Using the Acoustic Prepulse Inhibition Paradigm in Individuals at a Clinical High Risk for Psychosis.
Autorzy :
Bo Q; The National Clinical Research Center for Mental Disorders and Beijing Key Laboratory of Mental Disorders and Beijing Institute for Brain Disorders Center of Schizophrenia, Beijing Anding Hospital, Capital Medical University, Beijing, China.; Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China.
Mao Z; The National Clinical Research Center for Mental Disorders and Beijing Key Laboratory of Mental Disorders and Beijing Institute for Brain Disorders Center of Schizophrenia, Beijing Anding Hospital, Capital Medical University, Beijing, China.; Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China.
Tian Q; The National Clinical Research Center for Mental Disorders and Beijing Key Laboratory of Mental Disorders and Beijing Institute for Brain Disorders Center of Schizophrenia, Beijing Anding Hospital, Capital Medical University, Beijing, China.; Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China.
Yang N; Department of Psychiatry, First Affiliated Hospital of Henan University of Science and Technology, Luoyang, China.
Li X; The National Clinical Research Center for Mental Disorders and Beijing Key Laboratory of Mental Disorders and Beijing Institute for Brain Disorders Center of Schizophrenia, Beijing Anding Hospital, Capital Medical University, Beijing, China.; Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China.
Dong F; The National Clinical Research Center for Mental Disorders and Beijing Key Laboratory of Mental Disorders and Beijing Institute for Brain Disorders Center of Schizophrenia, Beijing Anding Hospital, Capital Medical University, Beijing, China.; Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China.
Zhou F; The National Clinical Research Center for Mental Disorders and Beijing Key Laboratory of Mental Disorders and Beijing Institute for Brain Disorders Center of Schizophrenia, Beijing Anding Hospital, Capital Medical University, Beijing, China.; Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China.
Li L; School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China.
Wang C; The National Clinical Research Center for Mental Disorders and Beijing Key Laboratory of Mental Disorders and Beijing Institute for Brain Disorders Center of Schizophrenia, Beijing Anding Hospital, Capital Medical University, Beijing, China.; Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China.
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Źródło :
Schizophrenia bulletin [Schizophr Bull] 2021 Jan 23; Vol. 47 (1), pp. 128-137.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Meta-Analysis of Sensorimotor Gating Deficits in Patients With Schizophrenia Evaluated by Prepulse Inhibition Test.
Autorzy :
San-Martin R; Center for Mathematics, Computation and Cognition, Universidade Federal do ABC, Santo André, Brazil.
Castro LA; Center for Mathematics, Computation and Cognition, Universidade Federal do ABC, Santo André, Brazil.
Menezes PR; Department of Preventive Medicine, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.; Population Mental Health Research Center, Universidade de São Paulo, São Paulo, Brazil.
Fraga FJ; Engineering, Modeling and Applied Social Sciences Center, Universidade Federal do ABC, Santo André, Brazil.
Simões PW; Engineering, Modeling and Applied Social Sciences Center, Universidade Federal do ABC, Santo André, Brazil.
Salum C; Center for Mathematics, Computation and Cognition, Universidade Federal do ABC, Santo André, Brazil.
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Źródło :
Schizophrenia bulletin [Schizophr Bull] 2020 Dec 01; Vol. 46 (6), pp. 1482-1497.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Toxoplasma gondii Effects on the Relationship of Kynurenine Pathway Metabolites to Acoustic Startle Latency in Schizophrenia vs. Control Subjects.
Autorzy :
Pearce BD; Rollins School of Public Health, Emory University, Atlanta, GA, United States.
Massa N; Rollins School of Public Health, Emory University, Atlanta, GA, United States.; Atlanta Veterans Affairs Health Care System, Decatur, GA, United States.
Goldsmith DR; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, United States.
Gandhi ZH; Rollins School of Public Health, Emory University, Atlanta, GA, United States.
Hankus A; Rollins School of Public Health, Emory University, Atlanta, GA, United States.
Alrohaibani A; Atlanta Veterans Affairs Health Care System, Decatur, GA, United States.
Goel N; Rollins School of Public Health, Emory University, Atlanta, GA, United States.
Cuthbert B; Atlanta Veterans Affairs Health Care System, Decatur, GA, United States.; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, United States.
Fargotstein M; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, United States.
Barr DB; Rollins School of Public Health, Emory University, Atlanta, GA, United States.
Panuwet P; Rollins School of Public Health, Emory University, Atlanta, GA, United States.
Brown VM; Rollins School of Public Health, Emory University, Atlanta, GA, United States.
Duncan E; Atlanta Veterans Affairs Health Care System, Decatur, GA, United States.; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, United States.
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Źródło :
Frontiers in psychiatry [Front Psychiatry] 2020 Nov 20; Vol. 11, pp. 552743. Date of Electronic Publication: 2020 Nov 20 (Print Publication: 2020).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Heritability of acoustic startle magnitude and latency from the consortium on the genetics of schizophrenia.
Autorzy :
Greenwood TA; Department of Psychiatry, University of California San Diego, La Jolla, CA, United States of America.
Swerdlow NR; Department of Psychiatry, University of California San Diego, La Jolla, CA, United States of America.
Sprock J; Department of Psychiatry, University of California San Diego, La Jolla, CA, United States of America.
Calkins ME; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, United States of America.
Freedman R; Department of Psychiatry, University of Colorado Health Sciences Center, Denver, CO, United States of America.
Green MF; VA Greater Los Angeles Healthcare System, Los Angeles, CA, United States of America; Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, United States of America.
Gur RE; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, United States of America.
Gur RC; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, United States of America.
Lazzeroni LC; Departments of Psychiatry and Behavioral Sciences and of Biomedical Data Science, Stanford University, Stanford, CA, United States of America; Department of Veterans Affairs Health Care System, Palo Alto, CA, United States of America.
Light GA; Department of Psychiatry, University of California San Diego, La Jolla, CA, United States of America; VISN-22 Mental Illness, Research, Education and Clinical Center (MIRECC), VA San Diego Healthcare System, San Diego, CA, United States of America.
Nuechterlein KH; Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, United States of America.
Radant AD; VA Puget Sound Health Care System, Seattle, WA, United States of America; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States of America.
Silverman JM; James J. Peters VA Medical Center, New York, NY, United States of America; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Stone WS; Department of Psychiatry, Harvard Medical School, Boston, MA, United States of America; Massachusetts Mental Health Center Public Psychiatry Division of the Beth Israel Deaconess Medical Center, Boston, MA, United States of America.
Sugar CA; Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, United States of America; Department of Biostatistics, University of California Los Angeles School of Public Health, Los Angeles, CA, United States of America.
Tsuang DW; VA Puget Sound Health Care System, Seattle, WA, United States of America; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States of America.
Tsuang MT; Department of Psychiatry, University of California San Diego, La Jolla, CA, United States of America.
Turetsky BI; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, United States of America.
Braff DL; Department of Psychiatry, University of California San Diego, La Jolla, CA, United States of America.
Duncan E; Atlanta Veterans Affairs Healthcare System, Decatur, GA, United States of America; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, United States of America. Electronic address: .
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Źródło :
Schizophrenia research [Schizophr Res] 2020 Oct; Vol. 224, pp. 33-39. Date of Electronic Publication: 2020 Nov 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Modulating microglia activation prevents maternal immune activation induced schizophrenia-relevant behavior phenotypes via arginase 1 in the dentate gyrus.
Autorzy :
Xia Y; South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Zhang Z; South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Lin W; Key Laboratory of Brain Functional Genomics, Ministry of Education and Shanghai, School of Life Science, East China Normal University, Shanghai, 200062, China.
Yan J; South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Zhu C; South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Yin D; Key Laboratory of Brain Functional Genomics, Ministry of Education and Shanghai, School of Life Science, East China Normal University, Shanghai, 200062, China.
He S; South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Su Y; South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Xu N; South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Caldwell RW; Department of Pharmacology and Toxicology, Augusta University, Augusta, GA, 30912, USA.
Yao L; South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China. .; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China. .
Chen Y; South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China. .; Center for Brain Science and Brain-Inspired Intelligence, Guangdong-Hong Kong-Macao Greater Bay Area, Guangzhou, 510515, China. .; Guangdong Province Key Laboratory of Psychiatric Disorders, Southern Medical University, Guangzhou, 510515, China. .
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Źródło :
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2020 Oct; Vol. 45 (11), pp. 1896-1908. Date of Electronic Publication: 2020 Jun 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Repeated norepinephrine receptor stimulation in the BNST induces sensorimotor gating deficits via corticotropin releasing factor.
Autorzy :
Rajbhandari AK; Dept. of Psychiatry and Neuroscience Training Program, University of Wisconsin-Madison, Madison, WI 53719, USA; AKR Is Now at Icahn School of Medicine at Mount Sinai, New York, 10029, USA. Electronic address: .
Bakshi VP; Dept. of Psychiatry and Neuroscience Training Program, University of Wisconsin-Madison, Madison, WI 53719, USA; AKR Is Now at Icahn School of Medicine at Mount Sinai, New York, 10029, USA.
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Źródło :
Neuropharmacology [Neuropharmacology] 2020 Aug 01; Vol. 172, pp. 108090. Date of Electronic Publication: 2020 Apr 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Striatal and Thalamic Auditory Response During Deep Brain Stimulation for Essential Tremor: Implications for Psychosis.
Autorzy :
Gault JM; Department of Neurosurgery, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA.; Department of Psychiatry, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA.
Thompson JA; Department of Neurosurgery, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA.
Maharajh K; Department of Psychiatry, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA.; Department of Neurology, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Hosokawa P; Department of Neurosurgery, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA.
Stevens KE; Department of Psychiatry, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA.
Olincy A; Department of Psychiatry, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA.
Liedtke EI; Department of Neurosurgery, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA.
Ojemann A; Department of Neurosurgery, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA.
Ojemann S; Department of Neurosurgery, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA.
Abosch A; Department of Neurosurgery, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA.; Department of Neurology, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
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Źródło :
Neuromodulation : journal of the International Neuromodulation Society [Neuromodulation] 2020 Jun; Vol. 23 (4), pp. 478-488. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji :
Journal Article
MeSH Terms :
Corpus Striatum/*physiopathology
Deep Brain Stimulation/*methods
Essential Tremor/*therapy
Evoked Potentials, Auditory/*physiology
Psychotic Disorders/*physiopathology
Thalamus/*physiopathology
Aged ; Female ; Humans ; Male ; Middle Aged ; Neural Pathways/physiopathology
Czasopismo naukowe
Tytuł :
Chronic inhibition of GABA synthesis in the infralimbic cortex facilitates conditioned safety memory and reduces contextual fear.
Autorzy :
Kreutzmann JC; Institute for Pharmacology & Toxicology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany. .; Leibniz Institute for Neurobiology, Magdeburg, Germany. .
Fendt M; Institute for Pharmacology & Toxicology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.; Center of Behavioral Brain Sciences, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
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Źródło :
Translational psychiatry [Transl Psychiatry] 2020 Apr 24; Vol. 10 (1), pp. 120. Date of Electronic Publication: 2020 Apr 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Studies on Haloperidol and Adjunctive α-Mangostin or Raw Garcinia mangostana Linn Pericarp on Bio-Behavioral Markers in an Immune-Inflammatory Model of Schizophrenia in Male Rats.
Autorzy :
Lotter J; Division of Pharmacology, Center of Excellence for Pharmaceutical Sciences, School of Pharmacy, North West University, Potchefstroom, South Africa.
Möller M; Division of Pharmacology, Center of Excellence for Pharmaceutical Sciences, School of Pharmacy, North West University, Potchefstroom, South Africa.
Dean O; Deakin University, IMPACT - The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia.; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia.
Berk M; Deakin University, IMPACT - The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Geelong, Australia.; Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia.; Orygen, Department of Psychiatry, The Centre of Excellence in Youth Mental Health, The University of Melbourne, Parkville, VIC, Australia.
Harvey BH; Division of Pharmacology, Center of Excellence for Pharmaceutical Sciences, School of Pharmacy, North West University, Potchefstroom, South Africa.
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Źródło :
Frontiers in psychiatry [Front Psychiatry] 2020 Mar 31; Vol. 11, pp. 121. Date of Electronic Publication: 2020 Mar 31 (Print Publication: 2020).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Melanin Concentrating Hormone Signaling Deficits in Schizophrenia: Association With Memory and Social Impairments and Abnormal Sensorimotor Gating.
Autorzy :
Vawter MP; Department of Psychiatry and Human Behavior, School of Medicine, University of California, Irvine, CA.
Schulmann A; Department of Psychiatry and Human Behavior, School of Medicine, University of California, Irvine, CA.; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA.
Alhassen L; Department of Psychiatry and Human Behavior, School of Medicine, University of California, Irvine, CA.
Alhassen W; Department of Pharmacology, School of Medicine, University of California, Irvine, CA.; Department of Pharmaceutical Sciences, University of California, Irvine, CA.
Hamzeh AR; John Curtin School of Medical Research, Australian National University, Canberra.
Sakr J; Department of Pharmaceutical Sciences, University of California, Irvine, CA.
Pauluk L; Department of Pharmacology, School of Medicine, University of California, Irvine, CA.
Yoshimura R; Department of Pharmacology, School of Medicine, University of California, Irvine, CA.
Wang X; Department of Pharmacology, School of Medicine, University of California, Irvine, CA.
Dai Q; Department of Pharmacology, School of Medicine, University of California, Irvine, CA.
Sanathara N; Department of Pharmacology, School of Medicine, University of California, Irvine, CA.
Civelli O; Department of Pharmacology, School of Medicine, University of California, Irvine, CA.; Department of Pharmaceutical Sciences, University of California, Irvine, CA.; Department of Developmental and Cell Biology, School of Medicine, University of California, Irvine, CA.
Alachkar A; Department of Pharmaceutical Sciences, University of California, Irvine, CA.
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Źródło :
The international journal of neuropsychopharmacology [Int J Neuropsychopharmacol] 2020 Mar 10; Vol. 23 (1), pp. 53-65.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypothalamic Hormones/*metabolism
Melanins/*metabolism
Memory Disorders/*physiopathology
Pituitary Hormones/*metabolism
Prefrontal Cortex/*metabolism
Receptors, Somatostatin/*deficiency
Receptors, Somatostatin/*metabolism
Schizophrenia/*metabolism
Schizophrenia/*physiopathology
Sensory Gating/*physiology
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Animals ; Behavior, Animal/physiology ; Child ; Child, Preschool ; Disease Models, Animal ; Female ; Fetus ; Humans ; Infant ; Male ; Memory Disorders/etiology ; Mice ; Mice, Knockout ; Middle Aged ; Schizophrenia/complications ; Young Adult
Czasopismo naukowe
Tytuł :
Expression of Behavioral Phenotypes in Genetic and Environmental Mouse Models of Schizophrenia.
Autorzy :
Sultana R; Neural Systems Laboratory, Department of Comparative Biomedical Sciences, Louisiana State University School of Veterinary Medicine, Baton Rouge, LA, United States.
Lee CC; Neural Systems Laboratory, Department of Comparative Biomedical Sciences, Louisiana State University School of Veterinary Medicine, Baton Rouge, LA, United States.
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Źródło :
Frontiers in behavioral neuroscience [Front Behav Neurosci] 2020 Feb 28; Vol. 14, pp. 29. Date of Electronic Publication: 2020 Feb 28 (Print Publication: 2020).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Relationship of prolonged acoustic startle latency to diagnosis and biotype in the bipolar-schizophrenia network on intermediate phenotypes (B-SNIP) cohort.
Autorzy :
Massa N; Atlanta Veterans Affairs Medical Center, Decatur, GA, 30033, USA; Rollins School of Public Health, Emory University, Atlanta, GA, 30322, USA.
Owens AV; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, 30329, USA.
Harmon W; Emory University, Atlanta, GA, 30322, USA.
Bhattacharya A; University of Washington, Seattle, WA, 98195, USA.
Ivleva EI; University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Keedy S; University of Chicago, Chicago, IL, 60637, USA.
Sweeney JA; Department of Psychiatry, University of Cincinnati, Cincinnati, OH, 45219, USA.
Pearlson GD; Yale University and Institute of Living, New Haven, CT, 06520, USA.
Keshavan MS; Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA, 02115, USA.
Tamminga CA; University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Clementz BA; Departments of Psychology and Neuroscience, Bio-Imaging Research Center, University of Georgia, Athens, GA, 30602, USA.
Duncan E; Atlanta Veterans Affairs Medical Center, Decatur, GA, 30033, USA; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, 30329, USA. Electronic address: .
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Źródło :
Schizophrenia research [Schizophr Res] 2020 Feb; Vol. 216, pp. 357-366. Date of Electronic Publication: 2019 Nov 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Czasopismo naukowe
Tytuł :
Dopamine D3 receptor: A neglected participant in Parkinson Disease pathogenesis and treatment?
Autorzy :
Yang P; Department of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, St. Louis, MO 63110, USA.
Perlmutter JS; Department of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, St. Louis, MO 63110, USA; Department of Neurology, Washington University School of Medicine, 510 S. Kingshighway Blvd, St. Louis, MO 63110, USA; Department of Neuroscience, Washington University School of Medicine, 510 S. Kingshighway Blvd, St. Louis, MO 63110, USA; Department of Physical Therapy, Washington University School of Medicine, 510 S. Kingshighway Blvd, St. Louis, MO 63110, USA; Department of Occupational Therapy, Washington University School of Medicine, 510 S. Kingshighway Blvd, St. Louis, MO 63110, USA.
Benzinger TLS; Department of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, St. Louis, MO 63110, USA.
Morris JC; Department of Neurology, Washington University School of Medicine, 510 S. Kingshighway Blvd, St. Louis, MO 63110, USA.
Xu J; Department of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, St. Louis, MO 63110, USA. Electronic address: .
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Źródło :
Ageing research reviews [Ageing Res Rev] 2020 Jan; Vol. 57, pp. 100994. Date of Electronic Publication: 2019 Nov 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Dopaminergic Neurons/*metabolism
Parkinson Disease/*metabolism
Receptors, Dopamine D3/*metabolism
Animals ; Dopamine/metabolism ; Dopaminergic Neurons/physiology ; Humans ; Parkinson Disease/drug therapy ; Parkinson Disease/physiopathology ; Receptors, Dopamine D3/agonists ; Receptors, Dopamine D3/antagonists & inhibitors ; alpha-Synuclein/metabolism
Czasopismo naukowe
Tytuł :
Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia.
Autorzy :
Shao Z; Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA.; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, Medical College, Xiamen University, Xiamen, Fujian, China.
Noh H; Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA.; Department of Cell biology and Anatomy, New York Medical College, Valhalla, NY, USA.
Bin Kim W; Department of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, CA, USA.
Ni P; Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA.; Department of Cell biology and Anatomy, New York Medical College, Valhalla, NY, USA.
Nguyen C; Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA.
Cote SE; Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA.
Noyes E; Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA.
Zhao J; Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA.
Parsons T; Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA.
Park JM; Department of Cell biology and Anatomy, New York Medical College, Valhalla, NY, USA.
Zheng K; Department of Cell biology and Anatomy, New York Medical College, Valhalla, NY, USA.
Park JJ; Department of Cell biology and Anatomy, New York Medical College, Valhalla, NY, USA.
Coyle JT; Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA.
Weinberger DR; Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, MD, USA.
Straub RE; Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, MD, USA.
Berman KF; Clinical and Translational Neuroscience Branch, National Institute of Mental Health, National Institutes of Health, Intramural Research Program, Baltimore, MD, USA.
Apud J; Clinical and Translational Neuroscience Branch, National Institute of Mental Health, National Institutes of Health, Intramural Research Program, Baltimore, MD, USA.
Ongur D; Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA.
Cohen BM; Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA.
McPhie DL; Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA.
Rapoport JL; Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD, USA.
Perlis RH; Center for Quantitative Health, Massachusetts General Hospital, Boston, MA, USA.
Lanz TA; Internal Medicine Research Unit, Pfizer Inc., Cambridge, MA, USA.
Xi HS; Computational Sciences, Pfizer Inc., Cambridge, MA, USA.
Yin C; Department of Pathology, New York Medical College, Valhalla, NY, USA.
Huang W; Department of Pathology, New York Medical College, Valhalla, NY, USA.
Hirayama T; KOKORO-Biology Group, Laboratories for Integrated Biology, Graduate School of Frontier Biosciences, Osaka University, Osaka Prefecture, Japan.; Department of Anatomy and Developmental Neurobiology, Tokushima University Graduate School of Medical Science, Tokushima, Japan.
Fukuda E; KOKORO-Biology Group, Laboratories for Integrated Biology, Graduate School of Frontier Biosciences, Osaka University, Osaka Prefecture, Japan.
Yagi T; KOKORO-Biology Group, Laboratories for Integrated Biology, Graduate School of Frontier Biosciences, Osaka University, Osaka Prefecture, Japan.
Ghosh S; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, MA, USA.
Eggan KC; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, MA, USA.
Kim HY; Department of Public Health, New York Medical College, Valhalla, NY, USA.
Eisenberg LM; New York Medical College/Westchester Medical Center Stem Cell Laboratory, Departments of Physiology and Medicine, New York Medical College, Valhalla, NY, USA.
Moghadam AA; Department of Cell biology and Anatomy, New York Medical College, Valhalla, NY, USA.
Stanton PK; Department of Cell biology and Anatomy, New York Medical College, Valhalla, NY, USA.
Cho JH; Department of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, CA, USA. .
Chung S; Department of Psychiatry, McLean Hospital/Harvard Medical School, Belmont, MA, USA. .; Department of Cell biology and Anatomy, New York Medical College, Valhalla, NY, USA. .
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Źródło :
Nature neuroscience [Nat Neurosci] 2019 Feb; Vol. 22 (2), pp. 229-242. Date of Electronic Publication: 2019 Jan 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cadherins/*metabolism
Interneurons/*metabolism
Prefrontal Cortex/*metabolism
Schizophrenia/*metabolism
Signal Transduction/*physiology
Animals ; Cadherins/genetics ; Female ; Humans ; Induced Pluripotent Stem Cells ; Interneurons/pathology ; Male ; Mice ; Mice, Knockout ; Prefrontal Cortex/pathology ; Schizophrenia/pathology ; Synapses/genetics ; Synapses/metabolism
Czasopismo naukowe
Tytuł :
Adolescent isolation rearing produces a prepulse inhibition deficit correlated with expression of the NMDA GluN1 subunit in the nucleus accumbens.
Autorzy :
Fitzgerald ML; Brain and Mind Research Institute, Weill Cornell Medicine, 407 East 61st Street, New York, NY, 10065, USA.; New York State Psychiatric Institute, Columbia University, New York, NY, 10032, USA.
Pickel VM; Brain and Mind Research Institute, Weill Cornell Medicine, 407 East 61st Street, New York, NY, 10065, USA. .
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Źródło :
Brain structure & function [Brain Struct Funct] 2018 Sep; Vol. 223 (7), pp. 3169-3181. Date of Electronic Publication: 2018 May 19.
Typ publikacji :
Journal Article
MeSH Terms :
Behavior, Animal*
Prepulse Inhibition*
Social Isolation*
Neurons/*metabolism
Nucleus Accumbens/*metabolism
Receptors, N-Methyl-D-Aspartate/*metabolism
Acoustic Stimulation ; Age Factors ; Animals ; Dendrites/metabolism ; Dendrites/ultrastructure ; Down-Regulation ; Housing, Animal ; Male ; Microscopy, Immunoelectron ; Neurons/ultrastructure ; Nucleus Accumbens/ultrastructure ; Rats, Sprague-Dawley ; Receptors, Dopamine D1/metabolism ; Synaptic Transmission
Czasopismo naukowe
Tytuł :
Cannabidiol Administered During Peri-Adolescence Prevents Behavioral Abnormalities in an Animal Model of Schizophrenia.
Autorzy :
Peres FF; Department of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.; National Institute for Translational Medicine, National Council for Scientific and Technological Development, Ribeirão Preto, Brazil.; Interdisciplinary Laboratory of Clinical Neurosciences, Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.
Diana MC; Department of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.; Interdisciplinary Laboratory of Clinical Neurosciences, Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.
Levin R; Department of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.; Interdisciplinary Laboratory of Clinical Neurosciences, Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.
Suiama MA; Department of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.; Interdisciplinary Laboratory of Clinical Neurosciences, Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.
Almeida V; Department of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.; Interdisciplinary Laboratory of Clinical Neurosciences, Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.
Vendramini AM; Department of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.; Interdisciplinary Laboratory of Clinical Neurosciences, Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.
Santos CM; Department of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.; Interdisciplinary Laboratory of Clinical Neurosciences, Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.
Zuardi AW; National Institute for Translational Medicine, National Council for Scientific and Technological Development, Ribeirão Preto, Brazil.; Department of Neuroscience and Behavior, University of São Paulo, Ribeirão Preto, Brazil.
Hallak JEC; National Institute for Translational Medicine, National Council for Scientific and Technological Development, Ribeirão Preto, Brazil.; Department of Neuroscience and Behavior, University of São Paulo, Ribeirão Preto, Brazil.
Crippa JA; National Institute for Translational Medicine, National Council for Scientific and Technological Development, Ribeirão Preto, Brazil.; Department of Neuroscience and Behavior, University of São Paulo, Ribeirão Preto, Brazil.
Abílio VC; Department of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.; National Institute for Translational Medicine, National Council for Scientific and Technological Development, Ribeirão Preto, Brazil.; Department of Neuroscience and Behavior, University of São Paulo, Ribeirão Preto, Brazil.
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Źródło :
Frontiers in pharmacology [Front Pharmacol] 2018 Aug 21; Vol. 9, pp. 901. Date of Electronic Publication: 2018 Aug 21 (Print Publication: 2018).
Typ publikacji :
Journal Article
Czasopismo naukowe

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