- Tytuł:
- Phosphodiesterase 4 inhibition enhances the dopamine D1 receptor/PKA/DARPP-32 signaling cascade in frontal cortex.
- Autorzy:
- Źródło:
- Psychopharmacology [Psychopharmacology (Berl)] 2012 Feb; Vol. 219 (4), pp. 1065-79. Date of Electronic Publication: 2011 Aug 11.
- Typ publikacji:
- Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
- MeSH Terms:
-
Cyclic AMP-Dependent Protein Kinases/*metabolism
Dopamine and cAMP-Regulated Phosphoprotein 32/*metabolism
Phosphodiesterase 4 Inhibitors/*pharmacology
Receptors, Dopamine D1/*metabolism
Animals ; Cyclic Nucleotide Phosphodiesterases, Type 4/drug effects ; Cyclic Nucleotide Phosphodiesterases, Type 4/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Neurons/metabolism ; Phosphorylation/drug effects ; Prefrontal Cortex/metabolism ; Pyramidal Cells/metabolism ; Rolipram/pharmacology ; Schizophrenia/physiopathology ; Sensory Gating ; Signal Transduction/drug effects
Czasopismo naukowe