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Wyświetlanie 1-14 z 14
Tytuł :
Rivastigmine improves isolation rearing-induced prepulse inhibition deficits via muscarinic acetylcholine receptors in mice.
Autorzy :
Higashino K; Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka, 565-0871, Japan.
Ago Y; Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka, 565-0871, Japan.
Umeki T; Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka, 565-0871, Japan.
Hasebe S; Department of Pharmacology, Graduate School of Dentistry, Osaka University, 1-8 Yamada-oka, Suita, Osaka, 565-0871, Japan.
Onaka Y; Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka, 565-0871, Japan.
Hashimoto H; Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka, 565-0871, Japan.; United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University and University of Fukui, 2-2 Yamada-oka, Suita, Osaka, 565-0871, Japan.
Takuma K; Department of Pharmacology, Graduate School of Dentistry, Osaka University, 1-8 Yamada-oka, Suita, Osaka, 565-0871, Japan.; United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University and University of Fukui, 2-2 Yamada-oka, Suita, Osaka, 565-0871, Japan.
Matsuda T; Laboratory of Medicinal Pharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka, 565-0871, Japan. .
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2016 Feb; Vol. 233 (3), pp. 521-8. Date of Electronic Publication: 2015 Oct 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cholinesterase Inhibitors/*pharmacology
Receptors, Muscarinic/*drug effects
Reflex, Startle/*drug effects
Rivastigmine/*pharmacology
Social Isolation/*psychology
Acetylcholine/metabolism ; Acoustic Stimulation ; Animals ; Brain Chemistry/drug effects ; Dopamine/metabolism ; Male ; Mecamylamine/pharmacology ; Mice ; Muscarinic Antagonists/pharmacology ; Nicotinic Antagonists/pharmacology ; Pirenzepine/analogs & derivatives ; Pirenzepine/pharmacology ; Prefrontal Cortex/drug effects ; Prefrontal Cortex/metabolism ; Receptor, Serotonin, 5-HT1A/drug effects
Czasopismo naukowe
Tytuł :
Reductions in synaptic proteins and selective alteration of prepulse inhibition in male C57BL/6 mice after postnatal administration of a VIP receptor (VIPR2) agonist.
Autorzy :
Ago Y; Semel Institute for Neuroscience and Human Behavior, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, 635 Charles E. Young Drive South, Los Angeles, CA, 90095, USA.
Condro MC
Tan YV
Ghiani CA
Colwell CS
Cushman JD
Fanselow MS
Hashimoto H
Waschek JA
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2015 Jun; Vol. 232 (12), pp. 2181-9. Date of Electronic Publication: 2015 Jan 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Nerve Tissue Proteins/*metabolism
Peptides, Cyclic/*pharmacology
Prepulse Inhibition/*drug effects
Receptors, Vasoactive Intestinal Peptide, Type II/*agonists
Synapses/*metabolism
Animals ; Animals, Newborn ; Disks Large Homolog 4 Protein ; Fear/drug effects ; Female ; Guanylate Kinases/metabolism ; Interpersonal Relations ; Male ; Membrane Proteins/metabolism ; Mice ; Mice, Inbred C57BL ; Motor Activity/drug effects ; Pregnancy ; Reflex, Startle/drug effects ; Signal Transduction/drug effects ; Synaptophysin/metabolism ; Vasoactive Intestinal Peptide/pharmacology
Czasopismo naukowe
Tytuł :
Effects of the nicotinic α7 receptor partial agonist GTS-21 on NMDA-glutamatergic receptor related deficits in sensorimotor gating and recognition memory in rats.
Autorzy :
Callahan PM; Department of Pharmacology and Toxicology, Small Animal Behavior Core, Georgia Regents University, Augusta, GA, 30912, USA, .
Terry AV Jr
Tehim A
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2014 Sep; Vol. 231 (18), pp. 3695-706. Date of Electronic Publication: 2014 Mar 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Benzylidene Compounds/*pharmacology
Nicotinic Agonists/*pharmacology
Pyridines/*pharmacology
Recognition, Psychology/*drug effects
Reflex, Startle/*drug effects
Sensory Gating/*drug effects
alpha7 Nicotinic Acetylcholine Receptor/*agonists
Animals ; Apomorphine/pharmacology ; Clozapine/pharmacology ; Cognition/drug effects ; Dizocilpine Maleate/pharmacology ; Excitatory Amino Acid Antagonists/pharmacology ; GABA Antagonists/pharmacology ; Haloperidol/pharmacology ; Male ; Rats ; Rats, Sprague-Dawley ; Rats, Wistar ; Receptors, N-Methyl-D-Aspartate ; Receptors, Nicotinic/physiology
Czasopismo naukowe
Tytuł :
Dexamphetamine effects on prepulse inhibition (PPI) and startle in healthy volunteers.
Autorzy :
Chitty K; Pharmacology, Pharmacy & Anaesthesiology Unit, School of Medicine and Pharmacology, Faculty of Medicine, Dentistry & Health Sciences, University of Western Australia, Perth, Western Australia, Australia.
Albrecht MA
Graham K
Kerr C
Lee JW
Iyyalol R
Martin-Iverson MT
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2014 Jun; Vol. 231 (11), pp. 2327-37. Date of Electronic Publication: 2013 Dec 18.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Sex Characteristics*
Central Nervous System Stimulants/*pharmacology
Dextroamphetamine/*pharmacology
Prepulse Inhibition/*drug effects
Reflex, Startle/*drug effects
Acoustic Stimulation ; Attention/drug effects ; Attention/physiology ; Double-Blind Method ; Female ; Humans ; Male ; Neuropsychological Tests ; Prepulse Inhibition/physiology ; Psychomotor Performance/drug effects ; Psychomotor Performance/physiology ; Psychopharmacology ; Reflex, Startle/physiology ; Young Adult
Czasopismo naukowe
Tytuł :
MitoPark mice, an animal model of Parkinson's disease, show enhanced prepulse inhibition of acoustic startle and no loss of gating in response to the adenosine A(2A) antagonist SCH 412348.
Autorzy :
Grauer SM; Neuroscience Franchise, Merck Research Laboratories, 2015 Galloping Hill Road, K-15-C209, Kenilworth, NJ, 07033, USA, .
Hodgson R
Hyde LA
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2014 Apr; Vol. 231 (7), pp. 1325-37. Date of Electronic Publication: 2013 Oct 23.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Models, Animal*
Adenosine A2 Receptor Antagonists/*pharmacology
Parkinson Disease/*physiopathology
Prepulse Inhibition/*drug effects
Prepulse Inhibition/*physiology
Pyrimidines/*pharmacology
Triazoles/*pharmacology
Aging/physiology ; Animals ; Apomorphine/pharmacology ; Benzothiazoles/pharmacology ; Dopamine Agonists/pharmacology ; Male ; Mice ; Mice, Transgenic ; Motor Activity/drug effects ; Pramipexole
Czasopismo naukowe
Tytuł :
Reduction in phencyclidine induced sensorimotor gating deficits in the rat following increased system xc⁻ activity in the medial prefrontal cortex.
Autorzy :
Lutgen V; Department of Biomedical Sciences, Marquette University, Suite 446, 561 N. 15th St, Milwaukee, WI 53233, USA.
Qualmann K
Resch J
Kong L
Choi S
Baker DA
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2013 Apr; Vol. 226 (3), pp. 531-40. Date of Electronic Publication: 2012 Nov 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Amino Acid Transport System y+/*metabolism
Prefrontal Cortex/*metabolism
Schizophrenia/*physiopathology
Sensory Gating/*physiology
Acetylcysteine/administration & dosage ; Acetylcysteine/pharmacology ; Amino Acid Transport System y+/genetics ; Amino Acid Transport Systems, Acidic ; Animals ; Benzoates/pharmacology ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Gait Disorders, Neurologic/etiology ; Glycine/analogs & derivatives ; Glycine/pharmacology ; In Situ Hybridization ; Male ; Phencyclidine/administration & dosage ; Phencyclidine/toxicity ; RNA, Messenger/metabolism ; Rats ; Rats, Sprague-Dawley ; Reflex, Startle
Czasopismo naukowe
Tytuł :
Phosphodiesterase 4 inhibition enhances the dopamine D1 receptor/PKA/DARPP-32 signaling cascade in frontal cortex.
Autorzy :
Kuroiwa M; Department of Pharmacology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan.
Snyder GL
Shuto T
Fukuda A
Yanagawa Y
Benavides DR
Nairn AC
Bibb JA
Greengard P
Nishi A
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2012 Feb; Vol. 219 (4), pp. 1065-79. Date of Electronic Publication: 2011 Aug 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cyclic AMP-Dependent Protein Kinases/*metabolism
Dopamine and cAMP-Regulated Phosphoprotein 32/*metabolism
Phosphodiesterase 4 Inhibitors/*pharmacology
Receptors, Dopamine D1/*metabolism
Animals ; Cyclic Nucleotide Phosphodiesterases, Type 4/drug effects ; Cyclic Nucleotide Phosphodiesterases, Type 4/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Neurons/metabolism ; Phosphorylation/drug effects ; Prefrontal Cortex/metabolism ; Pyramidal Cells/metabolism ; Rolipram/pharmacology ; Schizophrenia/physiopathology ; Sensory Gating ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Prenatal stress: role in psychotic and depressive diseases.
Autorzy :
Markham JA; Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD 21228, USA.
Koenig JI
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2011 Mar; Vol. 214 (1), pp. 89-106. Date of Electronic Publication: 2010 Oct 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Depressive Disorder/*etiology
Pregnancy Complications/*physiopathology
Psychotic Disorders/*etiology
Stress, Psychological/*complications
Adrenal Cortex Hormones/metabolism ; Animals ; Brain/embryology ; Brain/growth & development ; Cytokines/metabolism ; Depressive Disorder/physiopathology ; Female ; Humans ; Neurons/metabolism ; Pregnancy ; Psychotic Disorders/physiopathology ; Schizophrenia/etiology ; Schizophrenia/physiopathology
Czasopismo naukowe
Tytuł :
Effect of tandospirone, a serotonin-1A receptor partial agonist, on information processing and locomotion in dizocilpine-treated rats.
Autorzy :
Bubenikova-Valesova V; Department of Brain Pathophysiology and Biochemistry, Prague Psychiatric Centre, Prague, Czech Republic. />Svoboda J
Horacek J
Sumiyoshi T
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2010 Oct; Vol. 212 (2), pp. 267-76. Date of Electronic Publication: 2010 Jul 31.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Isoindoles/*pharmacology
Piperazines/*pharmacology
Pyrimidines/*pharmacology
Schizophrenia/*drug therapy
Serotonin Receptor Agonists/*pharmacology
Animals ; Antipsychotic Agents/pharmacology ; Disease Models, Animal ; Dizocilpine Maleate/toxicity ; Dose-Response Relationship, Drug ; Excitatory Amino Acid Antagonists/toxicity ; Haloperidol/pharmacology ; Isoindoles/administration & dosage ; Male ; Motor Activity/drug effects ; Piperazines/administration & dosage ; Pyrimidines/administration & dosage ; Rats ; Rats, Wistar ; Receptor, Serotonin, 5-HT1A/drug effects ; Receptor, Serotonin, 5-HT1A/metabolism ; Schizophrenia/physiopathology ; Sensory Gating/drug effects ; Serotonin Receptor Agonists/administration & dosage
Czasopismo naukowe
Tytuł :
Reelin haploinsufficiency reduces the density of PV+ neurons in circumscribed regions of the striatum and selectively alters striatal-based behaviors.
Autorzy :
Ammassari-Teule M; Department of Experimental Neurology, IRCCS Santa Lucia Foundation, Rome, Italy. />Sgobio C
Biamonte F
Marrone C
Mercuri NB
Keller F
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2009 Jun; Vol. 204 (3), pp. 511-21. Date of Electronic Publication: 2009 Mar 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Behavior, Animal/*physiology
Cell Adhesion Molecules, Neuronal/*genetics
Extracellular Matrix Proteins/*genetics
Neostriatum/*cytology
Neostriatum/*physiology
Nerve Tissue Proteins/*genetics
Neurons/*physiology
Parvalbumins/*genetics
Serine Endopeptidases/*genetics
Acoustic Stimulation ; Animals ; Avoidance Learning/physiology ; Cell Count ; Extinction, Psychological/physiology ; Fear/physiology ; Female ; Haplotypes ; Heterozygote ; Immunohistochemistry ; Interneurons/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Neurologic Mutants ; Nerve Net/cytology ; Nerve Net/physiology ; Psychomotor Performance/physiology ; gamma-Aminobutyric Acid/physiology
Czasopismo naukowe
Tytuł :
Realistic expectations of prepulse inhibition in translational models for schizophrenia research.
Autorzy :
Swerdlow NR; Department of Psychiatry, UCSD School of Medicine, La Jolla, CA, 92093-0804, USA, .
Weber M
Qu Y
Light GA
Braff DL
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2008 Aug; Vol. 199 (3), pp. 331-88. Date of Electronic Publication: 2008 Jun 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Models, Psychological*
Schizophrenic Psychology*
Antipsychotic Agents/*therapeutic use
Reflex, Startle/*drug effects
Reflex, Startle/*physiology
Schizophrenia/*drug therapy
Animals ; Disease Models, Animal ; Humans ; Reflex, Startle/genetics ; Schizophrenia/genetics
Czasopismo naukowe
Tytuł :
Galantamine and donepezil differently affect isolation rearing-induced deficits of prepulse inhibition in mice.
Autorzy :
Koda K; Laboratory of Medicinal Pharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka 565-0871, Japan.
Ago Y
Kawasaki T
Hashimoto H
Baba A
Matsuda T
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2008 Feb; Vol. 196 (2), pp. 293-301. Date of Electronic Publication: 2007 Oct 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Galantamine/*pharmacology
Indans/*pharmacology
Neural Inhibition/*drug effects
Piperidines/*pharmacology
Social Isolation/*psychology
Aconitine/analogs & derivatives ; Aconitine/pharmacology ; Acoustic Stimulation ; Analysis of Variance ; Animals ; Animals, Outbred Strains ; Apomorphine/pharmacology ; Behavior, Animal/drug effects ; Behavior, Animal/physiology ; Cholinesterase Inhibitors/pharmacology ; Dizocilpine Maleate/pharmacology ; Donepezil ; Dose-Response Relationship, Drug ; Male ; Mecamylamine/pharmacology ; Mice ; Neural Inhibition/physiology ; Nicotinic Antagonists/pharmacology ; Receptors, Nicotinic/physiology ; Reflex, Startle/drug effects ; Risperidone/pharmacology ; alpha7 Nicotinic Acetylcholine Receptor
Czasopismo naukowe
Tytuł :
Acute or subchronic clozapine treatment does not ameliorate prepulse inhibition (PPI) deficits in CPB-K mice with low levels of hippocampal NMDA receptor density.
Autorzy :
Wolf R; Department of Psychiatry, Otto-von-Guericke University, Leipziger Str. 44, 39120 Magdeburg, Germany. />Paelchen K
Matzke K
Dobrowolny H
Bogerts B
Schwegler H
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2007 Sep; Vol. 194 (1), pp. 93-102. Date of Electronic Publication: 2007 May 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acoustic Stimulation/*methods
Clozapine/*pharmacology
Neural Inhibition/*drug effects
Reflex, Startle/*drug effects
Analysis of Variance ; Animals ; Antipsychotic Agents/administration & dosage ; Antipsychotic Agents/pharmacology ; Clozapine/administration & dosage ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Hippocampus/drug effects ; Hippocampus/metabolism ; Humans ; Injections, Intraperitoneal ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred Strains ; Neural Inhibition/physiology ; Psychomotor Performance/drug effects ; Psychomotor Performance/physiology ; Receptors, N-Methyl-D-Aspartate/metabolism ; Reflex, Startle/physiology ; Schizophrenia/physiopathology ; Schizophrenic Psychology ; Time Factors
Czasopismo naukowe
Tytuł :
Putative antipsychotics with pronounced agonism at serotonin 5-HT1A and partial agonist activity at dopamine D2 receptors disrupt basal PPI of the startle reflex in rats.
Autorzy :
Auclair AL; Division of Neurobiology 2, Centre de Recherche Pierre Fabre, 17, avenue Jean Moulin, 81106, Castres, France. />Galinier A
Besnard J
Newman-Tancredi A
Depoortère R
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Źródło :
Psychopharmacology [Psychopharmacology (Berl)] 2007 Jul; Vol. 193 (1), pp. 45-54. Date of Electronic Publication: 2007 Mar 29.
Typ publikacji :
Journal Article
MeSH Terms :
Serotonin 5-HT1 Receptor Agonists*
Antipsychotic Agents/*pharmacology
Receptors, Dopamine D2/*agonists
Reflex, Startle/*drug effects
Animals ; Dopamine D2 Receptor Antagonists ; Dose-Response Relationship, Drug ; Male ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
    Wyświetlanie 1-14 z 14

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