- Tytuł:
- Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils.
- Autorzy:
- Źródło:
- Nature chemical biology [Nat Chem Biol] 2011 Nov 20; Vol. 8 (1), pp. 93-101. Date of Electronic Publication: 2011 Nov 20.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Amyloid/*chemistry
Oxazines/*chemistry
Peptide Fragments/*chemistry
Amino Acid Sequence ; Amyloid/toxicity ; Amyloid/ultrastructure ; Cell Line, Tumor ; Hippocampus/chemistry ; Hippocampus/drug effects ; Humans ; Hydrophobic and Hydrophilic Interactions ; Microscopy, Electron, Transmission ; Models, Molecular ; Peptide Fragments/toxicity ; Peptide Fragments/ultrastructure ; Protein Structure, Secondary ; Synaptic Transmission
Czasopismo naukowe