- Title:
- Celecoxib ameliorates non-alcoholic steatohepatitis in type 2 diabetic rats via suppression of the non-canonical Wnt signaling pathway expression.
- Authors:
- Source:
- PloS one [PLoS One] 2014 Jan 03; Vol. 9 (1), pp. e83819. Date of Electronic Publication: 2014 Jan 03 (Print Publication: 2014).
- Publication Type:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Cyclooxygenase 2 Inhibitors/*pharmacology
Diabetes Mellitus, Type 2/*complications
Diabetes Mellitus, Type 2/*metabolism
Fatty Liver/*complications
Fatty Liver/*metabolism
Pyrazoles/*pharmacology
Sulfonamides/*pharmacology
Wnt Signaling Pathway/*drug effects
Animals ; Biomarkers/blood ; Biomarkers/metabolism ; Celecoxib ; Cyclooxygenase 2/metabolism ; Cyclooxygenase 2 Inhibitors/administration & dosage ; Diet ; Fatty Liver/drug therapy ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Male ; Mitogen-Activated Protein Kinase 8/metabolism ; Non-alcoholic Fatty Liver Disease ; Organ Size/drug effects ; Pyrazoles/administration & dosage ; Rats ; Sulfonamides/administration & dosage ; Transcription Factor RelA/metabolism ; Wnt Proteins/metabolism ; Wnt-5a Protein
Academic Journal