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Tytuł:: Premature CD4+ T cell aging and its contribution to lymphopenia-induced proliferation of memory cells in autoimmune-prone non-obese diabetic mice.
Autorzy:: Sheu TT; Department of Immunology, Tzu Chi University, Hualien, Taiwan, Republic of China ; Institute of Microbiology, Immunology and Biochemistry, Tzu Chi University, Hualien, Taiwan, Republic of China.
Chiang BL; Graduate Institute of Immunology, National Taiwan University, Taipei, Taiwan, Republic of China ; Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan, Republic of China.
Yen JH; Department of Molecular Biology and Human Genetics, Tzu Chi University, Hualien, Taiwan, Republic of China.
Lin WC; Institute of Microbiology, Immunology and Biochemistry, Tzu Chi University, Hualien, Taiwan, Republic of China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Feb 26; Vol. 9 (2), pp. e89379. Date of Electronic Publication: 2014 Feb 26 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Proliferation*
Cellular Senescence*
Immunologic Memory*
CD4-Positive T-Lymphocytes/*immunology
Diabetes Mellitus, Experimental/*immunology
Lymphopenia/*immunology
Animals ; CD28 Antigens/immunology ; CD4-Positive T-Lymphocytes/cytology ; Female ; Interleukin-2/biosynthesis ; Mice ; Mice, Inbred BALB C ; Mice, Inbred NOD ; Obesity

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