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Tytuł:: Mitochondrial control by DRP1 in brain tumor initiating cells.
Autorzy:: Xie Q; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland, Ohio, USA.
Wu Q; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland, Ohio, USA.
Horbinski CM; Department of Pathology, University of Kentucky, Lexington, Kentucky, USA.
Flavahan WA; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland, Ohio, USA.
Yang K; 1] Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland, Ohio, USA. [2] Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, USA.
Zhou W; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland, Ohio, USA.
Dombrowski SM; Department of Neurological Surgery, Cleveland Clinic, Cleveland, Ohio, USA.
Huang Z; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland, Ohio, USA.
Fang X; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland, Ohio, USA.
Shi Y; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland, Ohio, USA.
Ferguson AN; Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, Virginia, USA.
Kashatus DF; Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, Virginia, USA.
Bao S; 1] Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland, Ohio, USA. [2] Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, USA.
Rich JN; 1] Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland, Ohio, USA. [2] Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, USA.; Pokaż więcej
Źródło:: Nature neuroscience [Nat Neurosci] 2015 Apr; Vol. 18 (4), pp. 501-10. Date of Electronic Publication: 2015 Mar 02.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Brain Neoplasms/*metabolism
GTP Phosphohydrolases/*metabolism
Glioblastoma/*metabolism
Microtubule-Associated Proteins/*metabolism
Mitochondria/*metabolism
Mitochondrial Proteins/*metabolism
Neoplastic Stem Cells/*metabolism
Apoptosis/drug effects ; Apoptosis/physiology ; Cell Line, Tumor ; Dynamins ; GTP Phosphohydrolases/antagonists & inhibitors ; Humans ; Microtubule-Associated Proteins/antagonists & inhibitors ; Mitochondria/ultrastructure ; Mitochondrial Proteins/antagonists & inhibitors ; Neoplastic Stem Cells/drug effects ; Phosphorylation/drug effects ; Phosphorylation/physiology ; Prognosis

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