PM: "28886017" - OpacWWW - Prolib Integro

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Tytuł:: B-cell phenotype and IgD-CD27- memory B cells are affected by TNF-inhibitors and tocilizumab treatment in rheumatoid arthritis.
Autorzy:: Moura RA; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Quaresma C; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Vieira AR; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Gonçalves MJ; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.; Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisbon Academic Medical Centre, Lisbon, Portugal.
Polido-Pereira J; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.; Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisbon Academic Medical Centre, Lisbon, Portugal.
Romão VC; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.; Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisbon Academic Medical Centre, Lisbon, Portugal.
Martins N; Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisbon Academic Medical Centre, Lisbon, Portugal.
Canhão H; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.; Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisbon Academic Medical Centre, Lisbon, Portugal.
Fonseca JE; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.; Rheumatology Department, Centro Hospitalar de Lisboa Norte, EPE, Hospital de Santa Maria, Lisbon Academic Medical Centre, Lisbon, Portugal.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 Sep 08; Vol. 12 (9), pp. e0182927. Date of Electronic Publication: 2017 Sep 08 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Immunologic Memory*
Antibodies, Monoclonal, Humanized/*therapeutic use
Arthritis, Rheumatoid/*drug therapy
Arthritis, Rheumatoid/*immunology
B-Lymphocyte Subsets/*immunology
Tumor Necrosis Factor-alpha/*antagonists & inhibitors
Antibodies, Monoclonal, Humanized/pharmacology ; Arthritis, Rheumatoid/diagnosis ; Arthritis, Rheumatoid/metabolism ; B-Lymphocyte Subsets/drug effects ; B-Lymphocyte Subsets/metabolism ; Biomarkers ; Chemokine CXCL13/blood ; Follow-Up Studies ; Gene Expression Profiling ; Gene Expression Regulation/drug effects ; Humans ; Immunoglobulin D/metabolism ; Immunophenotyping ; Lymphocyte Count ; Methotrexate/pharmacology ; Methotrexate/therapeutic use ; Phenotype ; Receptors, CXCR5/metabolism ; Receptors, IgE/blood ; Treatment Outcome ; Tumor Necrosis Factor Receptor Superfamily, Member 7/metabolism

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