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Tytuł :
Mitochondrial micropeptide STMP1 enhances mitochondrial fission to promote tumor metastasis.
Autorzy :
Xie C; Sun Yat-sen University, China.
Wang FY; Sun Yat-sen University, Guangzhou, China.
Sang Y; Sun Yat-sen University, Guangzhou, China.
Chen B; Sun Yat-sen University, Guangzhou, China.
Huang JH; Sun Yat-sen University, Guangzhou, China.
He FJ; Sun Yat-sen University, Guangzhou, China.
Li H; School of Life Sciences,Sun Yat-sen University, China.
Zhu Y; Sun Yat-sen University, Guangzhou, Guangdong, China.
Liu X; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, Guangdong, China.
Zhuang SM; Sun Yat-sen University, Guangzhou, Guangdong, China.
Fang JH; Sun Yat-sen University, Guangzhou, China.
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Źródło :
Cancer research [Cancer Res] 2022 May 11. Date of Electronic Publication: 2022 May 11.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Bimodal gene expression in cancer patients provides interpretable biomarkers for drug sensitivity.
Autorzy :
Ba-Alawi W; University Health Network, Toronto, Canada.
Kadambat Nair S; University Health Network, Toronto, Canada.
Li B; University of Toronto, Toronto, Canada.
Mammoliti A; University of Toronto, Toronto, Canada.
Smirnov P; University of Toronto, Toronto, ON, Canada.
Mer AS; University Health Network, Toronto, Canada.
Penn LZ; Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
Haibe-Kains B; University Health Network, Toronto, Ontario, Canada.
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Źródło :
Cancer research [Cancer Res] 2022 May 10. Date of Electronic Publication: 2022 May 10.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Hypoxia-reoxygenation couples 3βHSD1 enzyme and cofactor upregulation to facilitate androgen biosynthesis and hormone therapy resistance in prostate cancer.
Autorzy :
Qin L; Cleveland Clinic, Cleveland, OH, United States.
Chung YM; Cleveland Clinic, Cleveland, OH, United States.
Berk M; Cleveland Clinic, Cleveland, Ohio, United States.
Naelitz B; Cleveland Clinic, Cleveland, OH, United States.
Zhu Z; Cleveland Clinic, Cleveland, OH, United States.
Klein E; Cleveland Clinic, Cleveland, Ohio, United States.
Chakraborty AA; Cleveland Clinic Lerner College of Medicine, Cleveland, OH, United States.
Sharifi N; Cleveland Clinic, Cleveland, OH, United States.
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Źródło :
Cancer research [Cancer Res] 2022 May 10. Date of Electronic Publication: 2022 May 10.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Delineating The RAS Conformational Landscape.
Autorzy :
Parker MI; Drexel University College of Medicine, Philadelphia, PA, United States.
Meyer JE; Fox Chase Cancer Center, Philadelphia, PA, United States.
Golemis EA; Fox Chase Cancer Center, Philadelphia, PA, United States.
Dunbrack RL; Fox Chase Cancer Center, Philadelphia, PA, United States.
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Źródło :
Cancer research [Cancer Res] 2022 May 10. Date of Electronic Publication: 2022 May 10.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Computational identification of preneoplastic cells displaying high stemness and risk of cancer progression.
Autorzy :
Liu T; National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhao X; National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Lin Y; Peking University, Beijing, China.
Luo Q; Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Shanghai, China.
Zhang S; National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Xi Y; Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Chen Y; Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Lin L; Cancer Hospital of Chinese Academy of Medical Sciences, Beijing, China.
Fan W; Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yang J; National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Ma Y; National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Maity AK; Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Shanghai, China.
Huang Y; Peking University, Beijing, China.
Wang J; Tsinghua University, Beijingc, China.
Chang J; School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Lin D; National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Teschendorff AE; Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Shanghai, China.
Wu C; National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
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Źródło :
Cancer research [Cancer Res] 2022 May 10. Date of Electronic Publication: 2022 May 10.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Anti-HIV drug elvitegravir suppresses cancer metastasis via increased proteasomal degradation of m6A methyltransferase METTL3.
Autorzy :
Liao L; The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
He Y; The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Li SJ; First Affiliated Hospital of Jinan University, Guangzhou, China.
Zhang GG; The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yu W; Jinan University, Guangzhou, China.
Yang J; Jinan University, Guangzhou, China.
Huang ZJ; Jinan University, Guangzhou, Guangdong, China.
Zheng CC; The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
He QY; Jinan University, Guangzhou, China.
Li Y; Southern University of Science and Technology, Shenzhen, Guangdong, China.
Li B; The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
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Źródło :
Cancer research [Cancer Res] 2022 May 04. Date of Electronic Publication: 2022 May 04.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Establishment of the LNCaP Cell Line - The Dawn of an Era for Prostate Cancer Research.
Autorzy :
Abate-Shen C; Department of Molecular Pharmacology and Therapeutics, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York.; Department of Pathology and Cell Biology, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York.; Department of Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York.; Department of Urology, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York.
Nunes de Almeida F; Department of Molecular Pharmacology and Therapeutics, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York.
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Źródło :
Cancer research [Cancer Res] 2022 May 03; Vol. 82 (9), pp. 1689-1691.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Prostate*/pathology
Prostatic Neoplasms*/pathology
Androgens ; Cell Line ; Cell Transformation, Neoplastic ; Humans ; Male
Czasopismo naukowe
Tytuł :
No Back-up Plan: Loss of Isozyme Diversity as a Promising Therapeutic Strategy for Cancer.
Autorzy :
Kehinde AZ; Department of Biochemistry & Molecular Biology, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Parker SJ; Department of Biochemistry & Molecular Biology, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; British Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada.
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Źródło :
Cancer research [Cancer Res] 2022 May 03; Vol. 82 (9), pp. 1695-1697.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Isoenzymes*/metabolism
Neoplasms*/therapy
Humans
Opinia redakcyjna
Tytuł :
Secretion of IL1 by Dedifferentiated Melanoma Cells Inhibits JAK1-STAT3-Driven Actomyosin Contractility of Lymph Node Fibroblastic Reticular Cells.
Autorzy :
Rovera C; Mediterranean Center for Molecular Medicine (C3M), Institut National de la Santé et de la Recherche Médicale (Inserm) U1065, Université Côte d'Azur, Nice, France.; Team 11, Equipe labellisée Ligue Contre le Cancer, Nice, France.
Berestjuk I; Mediterranean Center for Molecular Medicine (C3M), Institut National de la Santé et de la Recherche Médicale (Inserm) U1065, Université Côte d'Azur, Nice, France.; Team 11, Equipe labellisée Ligue Contre le Cancer, Nice, France.
Lecacheur M; Mediterranean Center for Molecular Medicine (C3M), Institut National de la Santé et de la Recherche Médicale (Inserm) U1065, Université Côte d'Azur, Nice, France.; Team 11, Equipe labellisée Ligue Contre le Cancer, Nice, France.
Tavernier C; Mediterranean Center for Molecular Medicine (C3M), Institut National de la Santé et de la Recherche Médicale (Inserm) U1065, Université Côte d'Azur, Nice, France.; Team 11, Equipe labellisée Ligue Contre le Cancer, Nice, France.
Diazzi S; Mediterranean Center for Molecular Medicine (C3M), Institut National de la Santé et de la Recherche Médicale (Inserm) U1065, Université Côte d'Azur, Nice, France.; Team 11, Equipe labellisée Ligue Contre le Cancer, Nice, France.
Pisano S; Institute for Research on Cancer and Aging Nice (IRCAN), Université Côte d'Azur, CNRS, Institut National de la Santé et de la Recherche Médicale (Inserm), Nice, France.
Irondelle M; Mediterranean Center for Molecular Medicine (C3M), Institut National de la Santé et de la Recherche Médicale (Inserm) U1065, Université Côte d'Azur, Nice, France.
Mallavialle A; Mediterranean Center for Molecular Medicine (C3M), Institut National de la Santé et de la Recherche Médicale (Inserm) U1065, Université Côte d'Azur, Nice, France.; Team 11, Equipe labellisée Ligue Contre le Cancer, Nice, France.
Albrengues J; Institute for Research on Cancer and Aging Nice (IRCAN), Université Côte d'Azur, CNRS, Institut National de la Santé et de la Recherche Médicale (Inserm), Nice, France.
Gaggioli C; Institute for Research on Cancer and Aging Nice (IRCAN), Université Côte d'Azur, CNRS, Institut National de la Santé et de la Recherche Médicale (Inserm), Nice, France.
Girard CA; Mediterranean Center for Molecular Medicine (C3M), Institut National de la Santé et de la Recherche Médicale (Inserm) U1065, Université Côte d'Azur, Nice, France.; Team 11, Equipe labellisée Ligue Contre le Cancer, Nice, France.
Passeron T; Team 12, Mediterranean Center for Molecular Medicine (C3M), Université Côte d'Azur, Institut National de la Santé et de la Recherche Médicale (Inserm), Nice, France.; Department of Dermatology, Université Côte d'Azur, CHU Nice, Nice, France.
Deckert M; Mediterranean Center for Molecular Medicine (C3M), Institut National de la Santé et de la Recherche Médicale (Inserm) U1065, Université Côte d'Azur, Nice, France.; Team 11, Equipe labellisée Ligue Contre le Cancer, Nice, France.
Tartare-Deckert S; Mediterranean Center for Molecular Medicine (C3M), Institut National de la Santé et de la Recherche Médicale (Inserm) U1065, Université Côte d'Azur, Nice, France.; Team 11, Equipe labellisée Ligue Contre le Cancer, Nice, France.
Prod'homme V; Mediterranean Center for Molecular Medicine (C3M), Institut National de la Santé et de la Recherche Médicale (Inserm) U1065, Université Côte d'Azur, Nice, France.; Team 11, Equipe labellisée Ligue Contre le Cancer, Nice, France.
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Źródło :
Cancer research [Cancer Res] 2022 May 03; Vol. 82 (9), pp. 1774-1788.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Melanoma*/pathology
Skin Neoplasms*/pathology
Actomyosin/metabolism ; Animals ; Fibroblasts/metabolism ; Humans ; Interleukin-1 ; Janus Kinase 1/metabolism ; Lymph Nodes/pathology ; Mice ; STAT3 Transcription Factor/metabolism
Czasopismo naukowe
Tytuł :
JNK Signaling Promotes Bladder Cancer Immune Escape by Regulating METTL3-Mediated m6A Modification of PD-L1 mRNA.
Autorzy :
Ni Z; Department of Genetics, School of Life Science, Anhui Medical University, Hefei, Anhui, China.
Sun P; Department of Genetics, School of Life Science, Anhui Medical University, Hefei, Anhui, China.
Zheng J; Department of Pathology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Hongkou District, Shanghai, China.
Wu M; Department of Genetics, School of Life Science, Anhui Medical University, Hefei, Anhui, China.
Yang C; Department of Genetics, School of Life Science, Anhui Medical University, Hefei, Anhui, China.
Cheng M; Department of Genetics, School of Life Science, Anhui Medical University, Hefei, Anhui, China.
Yin M; Department of Genetics, School of Life Science, Anhui Medical University, Hefei, Anhui, China.
Cui C; Department of Genetics, School of Life Science, Anhui Medical University, Hefei, Anhui, China.
Wang G; Department of Genetics, School of Life Science, Anhui Medical University, Hefei, Anhui, China.
Yuan L; Department of Pathology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Hongkou District, Shanghai, China.
Gao Q; Department of Genetics, School of Life Science, Anhui Medical University, Hefei, Anhui, China.; Department of Anesthesiology, The Fourth Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Li Y; Department of Genetics, School of Life Science, Anhui Medical University, Hefei, Anhui, China.; Clinic Pathology Center, The Fourth Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
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Źródło :
Cancer research [Cancer Res] 2022 May 03; Vol. 82 (9), pp. 1789-1802.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Urinary Bladder Neoplasms*/pathology
Adenosine/metabolism ; B7-H1 Antigen/genetics ; Female ; Humans ; Male ; Membrane Glycoproteins ; Methyltransferases/genetics ; Methyltransferases/metabolism ; Mitogen-Activated Protein Kinase 8 ; Nerve Tissue Proteins ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
Whole-Genome Duplication Shapes the Aneuploidy Landscape of Human Cancers.
Autorzy :
Prasad K; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Bloomfield M; Department of Biological Sciences and Fralin Life Sciences Institute, Virginia Tech, Blacksburg Virginia.
Levi H; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Keuper K; Department of Molecular Genetics, TU Kaiserslautern, Kaiserslautern, Germany.
Bernhard SV; Department of Molecular Genetics, TU Kaiserslautern, Kaiserslautern, Germany.
Baudoin NC; Department of Biological Sciences and Fralin Life Sciences Institute, Virginia Tech, Blacksburg Virginia.
Leor G; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Eliezer Y; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Giam M; Skin Research Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Wong CK; Skin Research Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Rancati G; Skin Research Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Storchová Z; Department of Molecular Genetics, TU Kaiserslautern, Kaiserslautern, Germany.
Cimini D; Department of Biological Sciences and Fralin Life Sciences Institute, Virginia Tech, Blacksburg Virginia.
Ben-David U; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, School of Medicine, Tel Aviv University, Tel Aviv, Israel.
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Źródło :
Cancer research [Cancer Res] 2022 May 03; Vol. 82 (9), pp. 1736-1752.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Duplication*
Neoplasms*/genetics
Aneuploidy ; Carcinogenesis/genetics ; Genome ; Humans
Czasopismo naukowe
Tytuł :
Computational and Functional Analyses of HER2 Mutations Reveal Allosteric Activation Mechanisms and Altered Pharmacologic Effects.
Autorzy :
Ishiyama N; Black Diamond Therapeutics, Inc., New York, United States.
O'Connor M; Black Diamond Therapeutics Inc, Stony Brook, NY, United States.
Salomatov A; Black Diamond Therapeutics Inc, United States.
Romashko D; Black Diamond Therapeutics Inc, Stony Brook, New York, United States.
Thakur S; Black Diamond Therapeutics, New York, NY, United States.
Mentes A; Black Diamond Therapeutics, Inc., New York, United States.
Hopkins JF; Foundation Medicine, Inc., United States.
Frampton GM; Foundation Medicine Inc., Cambridge, MA, United States.
Albacker LA; Foundation Medicine, Inc., Cambridge, MA, United States.
Kohlmann A; BlackDiamond, Cambridge, United States.
Roberts C; Black Diamond Therapeutics, Inc., Cambridge, MA, United States.
Buck E; Black Diamond Therapeutics Inc, New York, NY, United States.
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Źródło :
Cancer research [Cancer Res] 2022 May 03. Date of Electronic Publication: 2022 May 03.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Expansion of Gastric Intestinal Metaplasia with Copy Number Aberrations Contributes to Field Cancerization.
Autorzy :
Kumagai K; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Shimizu T; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takai A; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kakiuchi N; Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takeuchi Y; Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan.; Clinical Bio Resource Center, Kyoto University Hospital, Kyoto, Japan.
Hirano T; Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takeda H; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Mizuguchi A; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Teramura M; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ito T; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Iguchi E; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Nikaido M; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Eso Y; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takahashi K; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ueda Y; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kobe University, Hyogo, Japan.
Miyamoto S; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Gastroenterology and Hepatology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Obama K; Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ogawa S; Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Marusawa H; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Osaka, Japan.
Seno H; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
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Źródło :
Cancer research [Cancer Res] 2022 May 03; Vol. 82 (9), pp. 1712-1723.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenocarcinoma*/genetics
Adenocarcinoma*/pathology
Helicobacter Infections*/complications
Helicobacter Infections*/genetics
Helicobacter pylori*
Precancerous Conditions*/genetics
Precancerous Conditions*/pathology
Stomach Neoplasms*/genetics
Stomach Neoplasms*/pathology
DNA Copy Number Variations ; Gastric Mucosa/pathology ; Humans ; Metaplasia/genetics ; Metaplasia/pathology
Czasopismo naukowe
Tytuł :
Comprehensive Evaluation of Machine Learning Models and Gene Expression Signatures for Prostate Cancer Prognosis Using Large Population Cohorts.
Autorzy :
Li R; Department of Botany and Plant Sciences, University of California, Riverside, California.; Graduate Program in Genetics, Genomics, and Bioinformatics, University of California, Riverside, California.
Zhu J; Department of Urology, Guizhou Provincial People's Hospital, Guizhou, China.
Zhong WD; Department of Urology, Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.; Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau, China.
Jia Z; Department of Botany and Plant Sciences, University of California, Riverside, California.; Graduate Program in Genetics, Genomics, and Bioinformatics, University of California, Riverside, California.
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Źródło :
Cancer research [Cancer Res] 2022 May 03; Vol. 82 (9), pp. 1832-1843.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Prostatic Neoplasms*/therapy
Transcriptome*
Gene Expression Profiling/methods ; Humans ; Machine Learning ; Male ; Prognosis ; Prospective Studies
Czasopismo naukowe
Tytuł :
Targeting Stearoyl-CoA Desaturase in Solid Tumors.
Autorzy :
Kubota CS
Espenshade PJ
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Źródło :
Cancer research [Cancer Res] 2022 May 03; Vol. 82 (9), pp. 1682-1688.
Typ publikacji :
Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Neoplasms*/pathology
Stearoyl-CoA Desaturase*/metabolism
Cell Transformation, Neoplastic ; Fatty Acids/metabolism ; Homeostasis/physiology ; Humans
Czasopismo naukowe
Tytuł :
Exploiting LRRC15 as a Novel Therapeutic Target in Cancer.
Autorzy :
Ray U; Division of Experimental Pathology and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota.
Pathoulas CL; School of Medicine, University of Connecticut, Farmington, Connecticut.
Thirusangu P; Division of Experimental Pathology and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota.
Purcell JW; Department of Oncology Drug Discovery, AbbVie, South San Francisco, California.
Kannan N; Division of Experimental Pathology and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota.
Shridhar V; Division of Experimental Pathology and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota.
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Źródło :
Cancer research [Cancer Res] 2022 May 03; Vol. 82 (9), pp. 1675-1681.
Typ publikacji :
Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cancer-Associated Fibroblasts*/metabolism
Glioblastoma*/metabolism
Immunoconjugates*/pharmacology
Sarcoma*/drug therapy
Humans ; Membrane Proteins/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Cardiac Dysfunction Promotes Cancer Progression via Multiple Secreted Factors.
Autorzy :
Awwad L
Aronheim A
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Źródło :
Cancer research [Cancer Res] 2022 May 03; Vol. 82 (9), pp. 1753-1761.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Heart Failure*/genetics
Heart Failure*/metabolism
Neoplasms*/complications
Activating Transcription Factor 3/genetics ; Activating Transcription Factor 3/metabolism ; Animals ; Cardiomegaly/genetics ; Cardiomegaly/metabolism ; Cardiomegaly/pathology ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Ventricular Remodeling
Czasopismo naukowe

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