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You search for a phrase ""2C"" according to the criterion: Subject Terms


Title:
Genome-wide identification and characterization of protein phosphatase 2C (PP2C) gene family in sunflower (Helianthus annuus L.) and their expression profiles in response to multiple abiotic stresses.
Authors:
Akter N; Department of Genetic Engineering and Biotechnology, Faculty of Biological Science and Technology, Jashore University of Science and Technology, Jashore, Bangladesh.
Islam MSU; Department of Genetic Engineering and Biotechnology, Faculty of Biological Science and Technology, Jashore University of Science and Technology, Jashore, Bangladesh.
Rahman MS; Department of Genetic Engineering and Biotechnology, Faculty of Biological Science and Technology, Jashore University of Science and Technology, Jashore, Bangladesh.
Zohra FT; Department of Genetic Engineering and Biotechnology, Faculty of Biological Sciences, University of Rajshahi, Rajshahi, Bangladesh.
Rahman SM; Department of Genetic Engineering and Biotechnology, Faculty of Biological Science and Technology, Jashore University of Science and Technology, Jashore, Bangladesh.
Manirujjaman M; Department of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, Louisiana, LA, United States of America.
Sarkar MAR; Department of Genetic Engineering and Biotechnology, Faculty of Biological Science and Technology, Jashore University of Science and Technology, Jashore, Bangladesh.
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Source:
PloS one [PLoS One] 2024 Mar 20; Vol. 19 (3), pp. e0298543. Date of Electronic Publication: 2024 Mar 20 (Print Publication: 2024).
Publication Type:
Journal Article
MeSH Terms:
Helianthus*/genetics
Protein Phosphatase 2C/genetics ; Genome, Plant ; Phylogeny ; Plant Breeding ; Multigene Family ; Stress, Physiological/genetics ; Gene Expression Regulation, Plant ; Plant Proteins/genetics
Academic Journal
Title:
Low WIP1 Expression Accelerates Ovarian Aging by Promoting Follicular Atresia and Primordial Follicle Activation.
Authors:
Zhou S; Department of Obstetrics and Gynecology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China.
Xi Y; Department of Obstetrics and Gynecology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China.
Chen Y; Department of Obstetrics and Gynecology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China.
Fu F; Department of Obstetrics and Gynecology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China.
Yan W; Department of Obstetrics and Gynecology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China.
Li M; Department of Obstetrics and Gynecology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China.
Wu Y; Department of Obstetrics and Gynecology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China.
Luo A; Department of Obstetrics and Gynecology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China.
Li Y; Department of Obstetrics and Gynecology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China.
Wang S; Department of Obstetrics and Gynecology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China.
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Source:
Cells [Cells] 2022 Dec 03; Vol. 11 (23). Date of Electronic Publication: 2022 Dec 03.
Publication Type:
Journal Article
MeSH Terms:
Follicular Atresia*
Ovarian Follicle*/metabolism
Ovarian Follicle*/pathology
Phosphatidylinositol 3-Kinases*/metabolism
Protein Phosphatase 2C*/metabolism
Animals ; Female ; Mice ; Aging
Academic Journal
Title:
Lipid Droplet Formation Is Regulated by Ser/Thr Phosphatase PPM1D via Dephosphorylation of Perilipin 1.
Authors:
Kamada R; Laboratory of Biological Chemistry, Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
Uno S; Laboratory of Biological Chemistry, Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
Kimura N; Laboratory of Biological Chemistry, Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
Yoshimura F; School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka 422-8526, Japan.
Tanino K; Laboratory of Organic Chemistry II, Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
Sakaguchi K; Laboratory of Biological Chemistry, Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 10; Vol. 23 (19). Date of Electronic Publication: 2022 Oct 10.
Publication Type:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*/metabolism
Lipid Droplets*/metabolism
Protein Phosphatase 2C*/metabolism
Adipocytes/metabolism ; Humans ; Hypertrophy/metabolism ; Lipid Metabolism ; Lipolysis ; Obesity/metabolism ; Perilipin-1/metabolism ; Perilipin-2/metabolism ; Phosphoric Monoester Hydrolases/metabolism ; Triglycerides/metabolism
Academic Journal
Title:
Low-Frequency PPM1D Gene Mutations Affect Treatment Response to CD19-Targeted CAR T-Cell Therapy in Large B-Cell Lymphoma.
Authors:
Seipel K; Department for Biomedical Research (DBMR), University of Bern, 3008 Bern, Switzerland.; Department of Medical Oncology, University Hospital Bern, 3010 Bern, Switzerland.
Frey M; Department of Medical Oncology, University Hospital Bern, 3010 Bern, Switzerland.
Nilius H; Department of Clinical Chemistry, University of Bern, 3010 Bern, Switzerland.
Akhoundova D; Department for Biomedical Research (DBMR), University of Bern, 3008 Bern, Switzerland.; Department of Medical Oncology, University Hospital Bern, 3010 Bern, Switzerland.
Banz Y; Institute of Tissue Medicine and Pathology (IGMP), University of Bern, 3010 Bern, Switzerland.
Bacher U; Department of Hematology, University Hospital Bern, 3010 Bern, Switzerland.
Pabst T; Department of Medical Oncology, University Hospital Bern, 3010 Bern, Switzerland.
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Source:
Current oncology (Toronto, Ont.) [Curr Oncol] 2023 Dec 13; Vol. 30 (12), pp. 10463-10476. Date of Electronic Publication: 2023 Dec 13.
Publication Type:
Journal Article
MeSH Terms:
Receptors, Chimeric Antigen*
Lymphoma, Large B-Cell, Diffuse*/therapy
Lymphoma, Large B-Cell, Diffuse*/drug therapy
Humans ; Immunotherapy, Adoptive/adverse effects ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/therapeutic use ; Treatment Outcome ; Antigens, CD19/genetics ; Antigens, CD19/therapeutic use ; Protein Phosphatase 2C/genetics
Academic Journal
Title:
MS: Wip1 suppresses angiogenesis through the STAT3-VEGF signalling pathway in serous ovarian cancer.
Authors:
Yin S; Department of Gynaecologic Oncology, Ovarian Cancer Program, Zhongshan Hospital, Fudan University, Shanghai, China.; Department of Obstetrics and Gynecology, Zhongshan Hospital, Fudan University, Shanghai, China.
Yang L; Department of Obstetrics and Gynecology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Zheng Y; Department of Gynaecologic Oncology, Ovarian Cancer Program, Zhongshan Hospital, Fudan University, Shanghai, China.
Zang R; Department of Gynaecologic Oncology, Ovarian Cancer Program, Zhongshan Hospital, Fudan University, Shanghai, China. .
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Source:
Journal of ovarian research [J Ovarian Res] 2022 May 10; Vol. 15 (1), pp. 56. Date of Electronic Publication: 2022 May 10.
Publication Type:
Journal Article
MeSH Terms:
Cystadenocarcinoma, Serous*/blood supply
Cystadenocarcinoma, Serous*/genetics
Cystadenocarcinoma, Serous*/metabolism
Ovarian Neoplasms*/blood supply
Ovarian Neoplasms*/pathology
Protein Phosphatase 2C*/genetics
Protein Phosphatase 2C*/metabolism
STAT3 Transcription Factor*/genetics
STAT3 Transcription Factor*/metabolism
Vascular Endothelial Growth Factor A*/genetics
Vascular Endothelial Growth Factor A*/metabolism
Carcinoma, Ovarian Epithelial/blood supply ; Carcinoma, Ovarian Epithelial/genetics ; Carcinoma, Ovarian Epithelial/metabolism ; Cell Line, Tumor ; Female ; Humans ; Neovascularization, Pathologic/genetics ; Signal Transduction
Academic Journal
Title:
Differential roles of the Wip1-p38-p53 DNA damage response pathway in early/advanced-stage ovarian clear cell carcinomas.
Authors:
Xu C; Doctoral Program in Obstetrics and Gynecology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tsukuba, Ibaraki, 305-8577, Japan.
Minaguchi T; Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tsukuba, Ibaraki, 305-8575, Japan. .
Qi N; Doctoral Program in Obstetrics and Gynecology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tsukuba, Ibaraki, 305-8577, Japan.
Fujieda K; Doctoral Program in Obstetrics and Gynecology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tsukuba, Ibaraki, 305-8577, Japan.
Suto A; Doctoral Program in Obstetrics and Gynecology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tsukuba, Ibaraki, 305-8577, Japan.
Itagaki H; Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tsukuba, Ibaraki, 305-8575, Japan.
Shikama A; Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tsukuba, Ibaraki, 305-8575, Japan.
Tasaka N; Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tsukuba, Ibaraki, 305-8575, Japan.
Akiyama A; Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tsukuba, Ibaraki, 305-8575, Japan.
Nakao S; Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tsukuba, Ibaraki, 305-8575, Japan.
Ochi H; Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tsukuba, Ibaraki, 305-8575, Japan.
Satoh T; Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tsukuba, Ibaraki, 305-8575, Japan.
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Source:
World journal of surgical oncology [World J Surg Oncol] 2022 Apr 30; Vol. 20 (1), pp. 139. Date of Electronic Publication: 2022 Apr 30.
Publication Type:
Journal Article
MeSH Terms:
Carcinoma*
Tumor Suppressor Protein p53*/metabolism
Protein Phosphatase 2C/*genetics
DNA Damage ; Humans ; Phosphoprotein Phosphatases/genetics ; Phosphoprotein Phosphatases/metabolism ; Protein Phosphatase 2C/metabolism
Academic Journal
Title:
Prognostic and immunological potential of PPM1G in lung adenocarcinoma.
Authors:
Yin R; Department of Thoracic Surgery, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong 264100, P.R. China.
Qu L; Department of Thoracic Surgery, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong 264100, P.R. China.
Wang Z; Department of Thoracic Surgery, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong 264100, P.R. China.
Tang J; Department of Thoracic Surgery, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong 264100, P.R. China.
Gu H; Department of Thoracic Surgery, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong 264100, P.R. China.
Wang X; Department of Endocrinology, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong 264100, P.R. China.
Yang D; School of Basic Medical Sciences, Binzhou Medical University, Yantai, Shandong 264003, P.R. China.
Du P; School of Basic Medical Sciences, Binzhou Medical University, Yantai, Shandong 264003, P.R. China.
Dong M; School of Basic Medical Sciences, Binzhou Medical University, Yantai, Shandong 264003, P.R. China.
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Source:
Molecular medicine reports [Mol Med Rep] 2023 Aug; Vol. 28 (2). Date of Electronic Publication: 2023 Jun 30.
Publication Type:
Journal Article
MeSH Terms:
Adenocarcinoma of Lung*/genetics
Lung Neoplasms*/genetics
Adenocarcinoma*/genetics
Humans ; Prognosis ; Databases, Protein ; Protein Phosphatase 2C/genetics
Academic Journal
Title:
Protein Phosphatase PP2C Identification in Entamoeba spp.
Authors:
Navarrete-Mena A; Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Ciudad de Mexico 11340, Mexico.; Unidad de Investigación UNAM-INC, División de Investigación, Facultad de Medicina, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de Mexico 14080, Mexico.
Pacheco-Yépez J; Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Ciudad de Mexico 11340, Mexico.
Hernández-Ramírez VI; Departamento de Infectómica y Patogénesis Molecular, Centro de Investigación y Estudios Avazados, CINVESTAV-IPN, Ciudad de México, CP 07360, Mexico.
Escalona-Montaño AR; Unidad de Investigación UNAM-INC, División de Investigación, Facultad de Medicina, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de Mexico 14080, Mexico.
Gómez-Sandoval JN; Universidad Politécnica del Valle de Toluca, Estado de Mexico 50904, Mexico.
Néquiz-Avendaño M; Unidad de Medicina Experimental, Facultad de Medicina, UNAM, Ciudad de Mexico 06726, Mexico.
Chávez-Munguía B; Departamento de Infectómica y Patogénesis Molecular, Centro de Investigación y Estudios Avazados, CINVESTAV-IPN, Ciudad de México, CP 07360, Mexico.
Tesoro-Cruz E; Unidad de Investigación Biomédica en Inmunología e Infectología, Hospital de Infectología, Centro Médico Nacional 'La Raza', IMSS, Ciudad de Mexico 02990, Mexico.
Talamás-Rohana P; Departamento de Infectómica y Patogénesis Molecular, Centro de Investigación y Estudios Avazados, CINVESTAV-IPN, Ciudad de México, CP 07360, Mexico.
Aguirre-García MM; Unidad de Investigación UNAM-INC, División de Investigación, Facultad de Medicina, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de Mexico 14080, Mexico.
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Source:
BioMed research international [Biomed Res Int] 2021 Oct 16; Vol. 2021, pp. 5746629. Date of Electronic Publication: 2021 Oct 16 (Print Publication: 2021).
Publication Type:
Journal Article
MeSH Terms:
Entamoeba/*enzymology
Protein Phosphatase 2C/*metabolism
Protozoan Proteins/*metabolism
Trophozoites/*enzymology
Amino Acid Sequence ; Animals ; Entamoeba/isolation & purification ; Entamoebiasis/parasitology ; Entamoebiasis/pathology ; Humans ; Phylogeny ; Protein Phosphatase 2C/chemistry ; Protein Phosphatase 2C/genetics ; Protozoan Proteins/chemistry ; Protozoan Proteins/genetics ; Sequence Homology, Amino Acid ; Trophozoites/isolation & purification
Academic Journal
Title:
Screening of selected ageing-related proteins that extend chronological life span in yeast Saccharomyces cerevisiae.
Authors:
Lee JW; Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 USM, Penang, Malaysia.; USM-RIKEN International Centre for Ageing Science (URICAS), Universiti Sains Malaysia, 11800 USM, Malaysia, Penang.
Ong TG; Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 USM, Penang, Malaysia.; USM-RIKEN International Centre for Ageing Science (URICAS), Universiti Sains Malaysia, 11800 USM, Malaysia, Penang.
Samian MR; USM-RIKEN International Centre for Ageing Science (URICAS), Universiti Sains Malaysia, 11800 USM, Malaysia, Penang.; School of Biological Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia.
Teh AH; USM-RIKEN International Centre for Ageing Science (URICAS), Universiti Sains Malaysia, 11800 USM, Malaysia, Penang.; Centre for Chemical Biology, Universiti Sains Malaysia, 11900 Bayan Lepas, Penang, Malaysia.
Watanabe N; USM-RIKEN International Centre for Ageing Science (URICAS), Universiti Sains Malaysia, 11800 USM, Malaysia, Penang.; Bioprobe Application Research Unit, RIKEN Centre for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.
Osada H; USM-RIKEN International Centre for Ageing Science (URICAS), Universiti Sains Malaysia, 11800 USM, Malaysia, Penang.; Chemical Biology Research Group, RIKEN Centre for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.
Ong EBB; Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 USM, Penang, Malaysia. .; USM-RIKEN International Centre for Ageing Science (URICAS), Universiti Sains Malaysia, 11800 USM, Malaysia, Penang. .
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Source:
Scientific reports [Sci Rep] 2021 Dec 17; Vol. 11 (1), pp. 24148. Date of Electronic Publication: 2021 Dec 17.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Proliferation*
Signal Transduction*
Protein Phosphatase 2C/*metabolism
Ribonucleoproteins, Small Nuclear/*metabolism
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Humans ; Protein Phosphatase 2C/genetics ; Ribonucleoproteins, Small Nuclear/genetics ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/genetics
Academic Journal
Title:
PPM1A as a key target of the application of Jiawei‑Maxing‑Shigan decoction for the attenuation of radiation‑induced epithelial‑mesenchymal transition in type II alveolar epithelial cells.
Authors:
Lu J; Oncology Department, Dingqiao Branch of GuangXing Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310007, P.R. China.
Lin S; Oncology Department, GuangXing Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310007, P.R. China.
Lin Z; Oncology Department, Dingqiao Branch of GuangXing Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310007, P.R. China.
Lin X; Oncology Department, Dingqiao Branch of GuangXing Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310007, P.R. China.
Shen Y; Graduate School, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310007, P.R. China.
Su J; Graduate School, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310007, P.R. China.
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Source:
Molecular medicine reports [Mol Med Rep] 2021 Nov; Vol. 24 (5). Date of Electronic Publication: 2021 Sep 24.
Publication Type:
Journal Article
MeSH Terms:
Alveolar Epithelial Cells/*drug effects
Alveolar Epithelial Cells/*metabolism
Drugs, Chinese Herbal/*chemistry
Drugs, Chinese Herbal/*pharmacology
Epithelial-Mesenchymal Transition/*drug effects
Epithelial-Mesenchymal Transition/*radiation effects
Protein Phosphatase 2C/*metabolism
Alveolar Epithelial Cells/radiation effects ; Animals ; Chromatography, High Pressure Liquid ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/radiation effects ; Protein Phosphatase 2C/genetics ; Rats ; Smad Proteins/genetics ; Smad Proteins/metabolism ; Spectrometry, Mass, Electrospray Ionization
Academic Journal
Title:
Downregulation of lncRNA PpL-T31511 and Pp-miRn182 Promotes Hydrogen Cyanamide-Induced Endodormancy Release through the PP2C-H 2 O 2 Pathway in Pear ( Pyrus pyrifolia ).
Authors:
Li L; College of Horticulture, Fujian Agriculture and Forestry University, Cangshan District, Fuzhou 350002, China.; Fruit Research Institute, Fujian Academy of Agricultural Sciences, Jinan District, Fuzhou 350013, China.
Liu J; College of Horticulture, Fujian Agriculture and Forestry University, Cangshan District, Fuzhou 350002, China.
Liang Q; College of Horticulture, Fujian Agriculture and Forestry University, Cangshan District, Fuzhou 350002, China.
Feng Y; College of Horticulture, Fujian Agriculture and Forestry University, Cangshan District, Fuzhou 350002, China.
Wang C; College of Horticulture, Fujian Agriculture and Forestry University, Cangshan District, Fuzhou 350002, China.
Wu S; College of Horticulture, Fujian Agriculture and Forestry University, Cangshan District, Fuzhou 350002, China.
Li Y; College of Horticulture, Fujian Agriculture and Forestry University, Cangshan District, Fuzhou 350002, China.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 31; Vol. 22 (21). Date of Electronic Publication: 2021 Oct 31.
Publication Type:
Journal Article
MeSH Terms:
Hydrogen Cyanide/*pharmacology
Hydrogen Peroxide/*metabolism
MicroRNAs/*metabolism
Plant Proteins/*metabolism
Protein Phosphatase 2C/*metabolism
Pyrus/*metabolism
RNA, Long Noncoding/*metabolism
RNA, Plant/*metabolism
Signal Transduction/*drug effects
MicroRNAs/genetics ; Plant Proteins/genetics ; Protein Phosphatase 2C/genetics ; Pyrus/genetics ; RNA, Long Noncoding/genetics ; RNA, Plant/genetics
Academic Journal
Title:
A novel assay for screening WIP1 phosphatase substrates in nuclear extracts.
Authors:
Storchova R; Cancer Cell Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.; Faculty of Science, Charles University, Prague, Czech Republic.
Burdova K; Cancer Cell Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
Palek M; Cancer Cell Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
Medema RH; Division of Cell Biology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Macurek L; Cancer Cell Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
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Source:
The FEBS journal [FEBS J] 2021 Oct; Vol. 288 (20), pp. 6035-6051. Date of Electronic Publication: 2021 May 27.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adaptor Proteins, Signal Transducing/*metabolism
Biological Assay/*methods
Bone Neoplasms/*pathology
Cell Nucleus/*metabolism
Osteosarcoma/*pathology
Protein Phosphatase 2C/*metabolism
Tumor Suppressor Protein p53/*metabolism
Acetylation ; Adaptor Proteins, Signal Transducing/genetics ; Bone Neoplasms/genetics ; Bone Neoplasms/metabolism ; Cell Nucleus/genetics ; DNA Damage ; DNA Repair ; Humans ; Osteosarcoma/genetics ; Osteosarcoma/metabolism ; Phosphorylation ; Protein Interaction Domains and Motifs ; Protein Phosphatase 2C/genetics ; Tumor Cells, Cultured ; Tumor Suppressor Protein p53/genetics
Academic Journal
Title:
Reciprocal regulation between the negative regulator PP2CG1 phosphatase and the positive regulator OST1 kinase confers cold response in Arabidopsis.
Authors:
Lv J; State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Liu J; State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Ming Y; State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Shi Y; State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Song C; Institute of Plant Stress Biology, Collaborative Innovation Center of Crop Stress Biology, Henan University, Kaifeng, 475001, China.
Gong Z; State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Yang S; State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Ding Y; State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
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Source:
Journal of integrative plant biology [J Integr Plant Biol] 2021 Aug; Vol. 63 (8), pp. 1568-1587. Date of Electronic Publication: 2021 May 31.
Publication Type:
Journal Article
MeSH Terms:
Cold Temperature*
Arabidopsis/*physiology
Arabidopsis Proteins/*metabolism
Protein Kinases/*metabolism
Protein Phosphatase 2C/*metabolism
Adaptation, Physiological ; Amino Acid Sequence ; Arabidopsis/genetics ; Arabidopsis Proteins/genetics ; Cold-Shock Response ; Epistasis, Genetic ; Freezing ; Models, Biological ; Phosphorylation ; Protein Binding ; Protein Phosphatase 2C/genetics ; Protein Stability
Academic Journal
Title:
Genome-Wide Identification and Abiotic Stress Response Analysis of PP2C Gene Family in Woodland and Pineapple Strawberries.
Authors:
Guo L; College of Horticulture, Gansu Agricultural University, Lanzhou 730070, China.
Lu S; College of Horticulture, Gansu Agricultural University, Lanzhou 730070, China.
Liu T; College of Horticulture, Gansu Agricultural University, Lanzhou 730070, China.
Nai G; College of Horticulture, Gansu Agricultural University, Lanzhou 730070, China.
Ren J; College of Horticulture, Gansu Agricultural University, Lanzhou 730070, China.
Gou H; College of Horticulture, Gansu Agricultural University, Lanzhou 730070, China.
Chen B; College of Horticulture, Gansu Agricultural University, Lanzhou 730070, China.
Mao J; College of Horticulture, Gansu Agricultural University, Lanzhou 730070, China.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 17; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 17.
Publication Type:
Journal Article
MeSH Terms:
Fragaria*/genetics
Ananas*/metabolism
Protein Phosphatase 2C/metabolism ; Phylogeny ; Stress, Physiological/genetics ; Phosphoprotein Phosphatases/metabolism ; Abscisic Acid/metabolism ; Forests ; Gene Expression Regulation, Plant ; Plant Proteins/genetics
Academic Journal
Title:
The Arabidopsis phosphatase PP2C49 negatively regulates salt tolerance through inhibition of AtHKT1;1.
Authors:
Chu M; State Key Laboratory for Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China.
Chen P; State Key Laboratory for Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China.
Meng S; State Key Laboratory for Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China.
Xu P; State Key Laboratory for Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China.
Lan W; State Key Laboratory for Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, 210023, China.
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Source:
Journal of integrative plant biology [J Integr Plant Biol] 2021 Mar; Vol. 63 (3), pp. 528-542. Date of Electronic Publication: 2020 Oct 10.
Publication Type:
Journal Article
MeSH Terms:
Arabidopsis/*enzymology
Arabidopsis/*physiology
Arabidopsis Proteins/*metabolism
Cation Transport Proteins/*antagonists & inhibitors
Protein Phosphatase 2C/*metabolism
Salt Tolerance/*physiology
Symporters/*antagonists & inhibitors
Abscisic Acid/metabolism ; Arabidopsis/genetics ; Arabidopsis Proteins/antagonists & inhibitors ; Arabidopsis Proteins/genetics ; Cation Transport Proteins/metabolism ; Gene Expression Regulation, Plant/drug effects ; Mutation/genetics ; Phenotype ; Plant Roots/drug effects ; Plant Roots/metabolism ; Plant Shoots/drug effects ; Plant Shoots/metabolism ; Protein Binding/drug effects ; Protein Phosphatase 2C/genetics ; Signal Transduction/drug effects ; Sodium/metabolism ; Sodium Chloride/pharmacology ; Subcellular Fractions/drug effects ; Subcellular Fractions/metabolism ; Symporters/metabolism ; Xylem/metabolism
Academic Journal
Title:
The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration.
Authors:
Zhou R; MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.; Department of Hepatobiliary and Pancreatic Surgery and Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wu Q; MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
Wang M; MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
Irani S; Department of Molecular Biosciences; Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America.
Li X; MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
Zhang Q; MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.; Department of Hepatobiliary and Pancreatic Surgery and Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Meng F; MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.; Department of Hepatobiliary and Pancreatic Surgery and Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Liu S; MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
Zhang F; MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
Wu L; Department of Hepatobiliary and Pancreatic Surgery and Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Lin X; Michael E. DeBakey Department of Surgery and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America.
Wang X; Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, China.
Zou J; Eye Center of the Second Affiliated Hospital School of Medicine, Institute of Translational Medicine, Zhejiang University, Hangzhou, China.
Song H; MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
Qin J; CAS Key Laboratory of Tissue Microenvironment and Tumor, Center for Excellence in Molecular Cell Science, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.
Liang T; Department of Hepatobiliary and Pancreatic Surgery and Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Feng XH; MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.; Michael E. DeBakey Department of Surgery and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America.
Zhang YJ; Department of Molecular Biosciences; Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America.
Xu P; MOE Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.; Department of Hepatobiliary and Pancreatic Surgery and Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
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Source:
PLoS biology [PLoS Biol] 2021 Feb 25; Vol. 19 (2), pp. e3001122. Date of Electronic Publication: 2021 Feb 25 (Print Publication: 2021).
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adaptor Proteins, Signal Transducing/*metabolism
Protein Phosphatase 2C/*metabolism
Regeneration/*physiology
Transcription Factors/*metabolism
Animals ; Cell Proliferation ; Cells, Cultured ; Colitis/pathology ; Humans ; Intestines/physiology ; Liver Regeneration/physiology ; Mice, Inbred C57BL ; Mice, Knockout ; Organoids ; Protein Phosphatase 2C/genetics ; Signal Transduction ; YAP-Signaling Proteins ; Mice
Academic Journal
Title:
OsPP2C09 Is a Bifunctional Regulator in Both ABA-Dependent and Independent Abiotic Stress Signaling Pathways.
Authors:
Min MK; Division of Metabolic Engineering, National Institute of Agricultural Sciences, RDA, Jeonju-si 54874, Korea.
Kim R; Division of Metabolic Engineering, National Institute of Agricultural Sciences, RDA, Jeonju-si 54874, Korea.
Hong WJ; Graduate School of Biotechnology & Crop Biotech Institute, Kyung Hee University, Yongin 17104, Korea.
Jung KH; Graduate School of Biotechnology & Crop Biotech Institute, Kyung Hee University, Yongin 17104, Korea.
Lee JY; Division of Metabolic Engineering, National Institute of Agricultural Sciences, RDA, Jeonju-si 54874, Korea.
Kim BG; Division of Metabolic Engineering, National Institute of Agricultural Sciences, RDA, Jeonju-si 54874, Korea.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 01; Vol. 22 (1). Date of Electronic Publication: 2021 Jan 01.
Publication Type:
Journal Article
MeSH Terms:
Signal Transduction*
Stress, Physiological*
Oryza/*enzymology
Protein Phosphatase 2C/*metabolism
Abscisic Acid/metabolism ; Droughts ; Gene Expression Regulation, Plant ; Oryza/genetics ; Oryza/physiology ; Osmotic Pressure ; Plant Proteins/metabolism ; Plant Proteins/physiology ; Protein Phosphatase 2C/physiology
Academic Journal
Title:
Pervasive duplication, biased molecular evolution and comprehensive functional analysis of the PP2C family in Glycine max.
Authors:
Fan K; Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, College of Agriculture, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Fujian Provincial Key Laboratory of Agroecological Processing and Safety Monitoring, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Key Laboratory of Crop Ecology and Molecular Physiology (Fujian Agriculture and Forestry University), Fujian Province University, Fuzhou, 35002, P. R. China.
Chen Y; Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, College of Agriculture, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Fujian Provincial Key Laboratory of Agroecological Processing and Safety Monitoring, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Key Laboratory of Crop Ecology and Molecular Physiology (Fujian Agriculture and Forestry University), Fujian Province University, Fuzhou, 35002, P. R. China.
Mao Z; Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, College of Agriculture, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Fujian Provincial Key Laboratory of Agroecological Processing and Safety Monitoring, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Key Laboratory of Crop Ecology and Molecular Physiology (Fujian Agriculture and Forestry University), Fujian Province University, Fuzhou, 35002, P. R. China.
Fang Y; Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, College of Agriculture, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Fujian Provincial Key Laboratory of Agroecological Processing and Safety Monitoring, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Key Laboratory of Crop Ecology and Molecular Physiology (Fujian Agriculture and Forestry University), Fujian Province University, Fuzhou, 35002, P. R. China.
Li Z; Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, College of Agriculture, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Fujian Provincial Key Laboratory of Agroecological Processing and Safety Monitoring, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Key Laboratory of Crop Ecology and Molecular Physiology (Fujian Agriculture and Forestry University), Fujian Province University, Fuzhou, 35002, P. R. China.
Lin W; Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, College of Agriculture, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Fujian Provincial Key Laboratory of Agroecological Processing and Safety Monitoring, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Key Laboratory of Crop Ecology and Molecular Physiology (Fujian Agriculture and Forestry University), Fujian Province University, Fuzhou, 35002, P. R. China.
Zhang Y; Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, College of Agriculture, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Fujian Provincial Key Laboratory of Agroecological Processing and Safety Monitoring, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Key Laboratory of Crop Ecology and Molecular Physiology (Fujian Agriculture and Forestry University), Fujian Province University, Fuzhou, 35002, P. R. China.
Liu J; Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, College of Agriculture, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Fujian Provincial Key Laboratory of Agroecological Processing and Safety Monitoring, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Key Laboratory of Crop Ecology and Molecular Physiology (Fujian Agriculture and Forestry University), Fujian Province University, Fuzhou, 35002, P. R. China.
Huang J; Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, College of Agriculture, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Fujian Provincial Key Laboratory of Agroecological Processing and Safety Monitoring, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China.; Key Laboratory of Crop Ecology and Molecular Physiology (Fujian Agriculture and Forestry University), Fujian Province University, Fuzhou, 35002, P. R. China.
Lin W; Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, College of Agriculture, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China. .; Fujian Provincial Key Laboratory of Agroecological Processing and Safety Monitoring, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, 350002, P. R. China. .; Key Laboratory of Crop Ecology and Molecular Physiology (Fujian Agriculture and Forestry University), Fujian Province University, Fuzhou, 35002, P. R. China. .
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Source:
BMC genomics [BMC Genomics] 2020 Jul 06; Vol. 21 (1), pp. 465. Date of Electronic Publication: 2020 Jul 06.
Publication Type:
Journal Article
MeSH Terms:
Evolution, Molecular*
Gene Duplication*
Protein Phosphatase 2C/*genetics
Glycine max/*enzymology
Gene Regulatory Networks ; Genes, Plant ; Genomics ; Magnoliopsida/genetics ; Multigene Family ; Nucleotide Motifs ; Phylogeny ; Protein Phosphatase 2C/metabolism ; RNA-Seq ; Regulatory Elements, Transcriptional ; Glycine max/genetics ; Glycine max/growth & development
Academic Journal
Title:
Platyconic acid A‑induced PPM1A upregulation inhibits the proliferation, inflammation and extracellular matrix deposition of TGF‑β1‑induced lung fibroblasts.
Authors:
Su C; Pneumology Department, Nantong Hospital of Traditional Chinese Medicine, Nantong Affiliated Hospital of Nanjing University of Chinese Medicine, Nantong, Jiangsu 226500, P.R. China.
Tang Y; Pneumology Department, Nantong Hospital of Traditional Chinese Medicine, Nantong Affiliated Hospital of Nanjing University of Chinese Medicine, Nantong, Jiangsu 226500, P.R. China.
Wang C; Pneumology Department, Nantong Hospital of Traditional Chinese Medicine, Nantong Affiliated Hospital of Nanjing University of Chinese Medicine, Nantong, Jiangsu 226500, P.R. China.
Huang H; Pneumology Department, Nantong Hospital of Traditional Chinese Medicine, Nantong Affiliated Hospital of Nanjing University of Chinese Medicine, Nantong, Jiangsu 226500, P.R. China.
Hou H; Pneumology Department, Nantong Hospital of Traditional Chinese Medicine, Nantong Affiliated Hospital of Nanjing University of Chinese Medicine, Nantong, Jiangsu 226500, P.R. China.
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Source:
Molecular medicine reports [Mol Med Rep] 2022 Nov; Vol. 26 (5). Date of Electronic Publication: 2022 Sep 07.
Publication Type:
Journal Article
MeSH Terms:
Pulmonary Fibrosis*/metabolism
Saponins*/pharmacology
Cell Proliferation ; Extracellular Matrix/metabolism ; Fibroblasts/metabolism ; Humans ; Inflammation/metabolism ; Lung/metabolism ; Protein Phosphatase 2C/genetics ; Protein Phosphatase 2C/metabolism ; RNA, Messenger/metabolism ; Transforming Growth Factor beta1/metabolism ; Triterpenes ; Up-Regulation ; beta Catenin/metabolism
Academic Journal
Title:
Transcriptome-wide identification of walnut PP2C family genes in response to external stimulus.
Authors:
Sisi C; Labortory of Walnut Research Center, College of Forestry, Northwest A & F University, Yangling, 712100, Shaanxi, China.
Jieru D; Labortory of Walnut Research Center, College of Forestry, Northwest A & F University, Yangling, 712100, Shaanxi, China.
Peidong C; Labortory of Walnut Research Center, College of Forestry, Northwest A & F University, Yangling, 712100, Shaanxi, China.
Zhaolong Z; Labortory of Walnut Research Center, College of Forestry, Northwest A & F University, Yangling, 712100, Shaanxi, China.
Yihang W; Labortory of Walnut Research Center, College of Forestry, Northwest A & F University, Yangling, 712100, Shaanxi, China.
Shuwen C; Labortory of Walnut Research Center, College of Forestry, Northwest A & F University, Yangling, 712100, Shaanxi, China.
Yan T; Labortory of Walnut Research Center, College of Forestry, Northwest A & F University, Yangling, 712100, Shaanxi, China.
Tianyu W; Labortory of Walnut Research Center, College of Forestry, Northwest A & F University, Yangling, 712100, Shaanxi, China.
Guiyan Y; Labortory of Walnut Research Center, College of Forestry, Northwest A & F University, Yangling, 712100, Shaanxi, China. .; Key Laboratory of Economic Plant Resources Development and Utilization in Shaanxi Province, College of Forestry, Northwest A & F University, Yangling, 712100, Shaanxi, China. .
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Source:
BMC genomics [BMC Genomics] 2022 Sep 08; Vol. 23 (1), pp. 640. Date of Electronic Publication: 2022 Sep 08.
Publication Type:
Journal Article
MeSH Terms:
Gene Expression Regulation, Plant*
Juglans*/genetics
Amino Acids/metabolism ; Phylogeny ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Protein Phosphatase 2C/genetics ; Protein Phosphatase 2C/metabolism ; Transcriptome
Academic Journal

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