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Wyszukujesz frazę ""3-Nitropropionic acid"" wg kryterium: Temat


Tytuł :
Protective Effect of Natural Products against Huntington's Disease: An Overview of Scientific Evidence and Understanding Their Mechanism of Action.
Autorzy :
Lum PT; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur Royal College of Medicine Perak, Ipoh, 30450 Perak, Malaysia.
Sekar M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur Royal College of Medicine Perak, Ipoh, 30450 Perak, Malaysia.
Gan SH; School of Pharmacy, Monash University Malaysia, Bandar Sunway, 47500 Selangor Darul Ehsan, Malaysia.
Bonam SR; Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Equipe-Immunopathologie et Immunointervention Thérapeutique, Sorbonne Université, Université de Paris, Paris 75006, France.
Shaikh MF; Neuropharmacology Research Strength, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, 47500 Selangor, Malaysia.
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Źródło :
ACS chemical neuroscience [ACS Chem Neurosci] 2021 Jan 21. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Plasma l-indospicine and 3-nitropropionic acid in ponies fed creeping indigo: Comparison with results from an episode of presumptive creeping indigo toxicosis.
Autorzy :
Darby S; University of Florida College of Veterinary Medicine, Department of Large Animal Clinical Sciences, 2015 SW 16th Avenue, 2015 SW 16th Avenue, PO Box 100136, Gainesville, FL, 32610, USA.
Sanchez LC; University of Florida College of Veterinary Medicine, Department of Large Animal Clinical Sciences, 2015 SW 16th Avenue, 2015 SW 16th Avenue, PO Box 100136, Gainesville, FL, 32610, USA.
Mallicote MF; University of Florida College of Veterinary Medicine, Department of Large Animal Clinical Sciences, 2015 SW 16th Avenue, 2015 SW 16th Avenue, PO Box 100136, Gainesville, FL, 32610, USA.
House AM; University of Florida College of Veterinary Medicine, Department of Large Animal Clinical Sciences, 2015 SW 16th Avenue, 2015 SW 16th Avenue, PO Box 100136, Gainesville, FL, 32610, USA.
Plummer CE; University of Florida College of Veterinary Medicine, Departments of Small and Large Animal Clinical Sciences, 2015 SW 16th Avenue, PO Box 100126, Gainesville, FL, 32610-0126, USA.
Nadruz V; Kansas State University Veterinary Health Center, 1800 Denison Ave, Manhattan, KS, 66506, USA.
Benmoha RH
Roberts SM; University of Florida, Center for Environmental and Human Toxicology, 2187 Mowry Rd, Gainesville, FL, 32611, USA.
Derendorf H; University of Florida College of Pharmacy, Department of Pharmaceutics, 1225 Center Drive, Gainesville, FL, 32610-0494, USA.
Silva-Sanchez C; University of Florida, Center for Environmental and Human Toxicology, 2187 Mowry Rd, Gainesville, FL, 32611, USA.
Claire J; University of Florida College of Veterinary Medicine, Department of Large Animal Clinical Sciences, 2015 SW 16th Avenue, 2015 SW 16th Avenue, PO Box 100136, Gainesville, FL, 32610, USA.
MacKay RJ; University of Florida College of Veterinary Medicine, Department of Large Animal Clinical Sciences, 2015 SW 16th Avenue, 2015 SW 16th Avenue, PO Box 100136, Gainesville, FL, 32610, USA.
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Źródło :
Equine veterinary journal [Equine Vet J] 2020 Dec 28. Date of Electronic Publication: 2020 Dec 28.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Bilateral striatal transplantation of human olfactory stem cells ameliorates motor function, prevents necroptosis-induced cell death and improves striatal volume in the rat model of Huntington's disease.
Autorzy :
Bayat AH; Department of Neuroscience, Saveh University of Medical Sciences, Saveh, Iran. Electronic address: .
Saeidikhoo S; Neuroscience Lab, Anatomy and Cell Biology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
Ebrahimi V; Department of Anatomy and Cell Biology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: .
Mesgar S; Neuroscience Lab, Anatomy and Cell Biology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
Joneidi M; Neuroscience Lab, Anatomy and Cell Biology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
Soltani R; Neuroscience Lab, Anatomy and Cell Biology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
Aghajanpour F; Neuroscience Lab, Anatomy and Cell Biology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
Mohammadzadeh I; Neuroscience Lab, Anatomy and Cell Biology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
Torabi A; Neuroscience Lab, Anatomy and Cell Biology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
Abdollahifar MA; Neuroscience Lab, Anatomy and Cell Biology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
Bagher Z; ENT and Head and Neck Research Center and Department, Hazrat Rasoul Akram Hospital, The Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran. Electronic address: .
Alizadeh R; ENT and Head and Neck Research Center and Department, Hazrat Rasoul Akram Hospital, The Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran. Electronic address: .
Aliaghaei A; Neuroscience Lab, Anatomy and Cell Biology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
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Źródło :
Journal of chemical neuroanatomy [J Chem Neuroanat] 2020 Dec 02; Vol. 112, pp. 101903. Date of Electronic Publication: 2020 Dec 02.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Ginsenoside Rg1 exerts neuroprotective effects in 3-nitropronpionic acid-induced mouse model of Huntington's disease via suppressing MAPKs and NF-κB pathways in the striatum.
Autorzy :
Yang X; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Chu SF; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Wang ZZ; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Li FF; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Yuan YH; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Chen NH; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. .
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Źródło :
Acta pharmacologica Sinica [Acta Pharmacol Sin] 2020 Nov 19. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Astrocytes from cortex and striatum show differential responses to mitochondrial toxin and BDNF: implications for protection of striatal neurons expressing mutant huntingtin.
Autorzy :
Saba J; Instituto de Investigaciones Biomédicas (INBIOMED), UBA-CONICET, Paraguay 2155, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
López Couselo F; Instituto de Investigaciones Biomédicas (INBIOMED), UBA-CONICET, Paraguay 2155, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Turati J; Instituto de Investigaciones Biomédicas (INBIOMED), UBA-CONICET, Paraguay 2155, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Carniglia L; Instituto de Investigaciones Biomédicas (INBIOMED), UBA-CONICET, Paraguay 2155, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Durand D; Instituto de Investigaciones Biomédicas (INBIOMED), UBA-CONICET, Paraguay 2155, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
de Laurentiis A; Centro de Estudios Farmacológicos y Botánicos (CEFYBO). UBA-CONICET, Paraguay 2155, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Lasaga M; Instituto de Investigaciones Biomédicas (INBIOMED), UBA-CONICET, Paraguay 2155, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Caruso C; Instituto de Investigaciones Biomédicas (INBIOMED), UBA-CONICET, Paraguay 2155, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina. .
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Źródło :
Journal of neuroinflammation [J Neuroinflammation] 2020 Oct 06; Vol. 17 (1), pp. 290. Date of Electronic Publication: 2020 Oct 06.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Dapagliflozin improves behavioral dysfunction of Huntington's disease in rats via inhibiting apoptosis-related glycolysis.
Autorzy :
El-Sahar AE; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt. Electronic address: .
Rastanawi AA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt. Electronic address: .
El-Yamany MF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt. Electronic address: .
Saad MA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt; School of Pharmacy, Newgiza University, Cairo, Egypt. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Sep 15; Vol. 257, pp. 118076. Date of Electronic Publication: 2020 Jul 10.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Benzhydryl Compounds/*pharmacology
Glucosides/*pharmacology
Glycolysis/*drug effects
Huntington Disease/*drug therapy
Sodium-Glucose Transporter 2 Inhibitors/*pharmacology
Animals ; Autophagy/drug effects ; Behavior, Animal/drug effects ; Disease Models, Animal ; Huntington Disease/physiopathology ; Inflammation/drug therapy ; Inflammation/pathology ; Male ; Maze Learning/drug effects ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
The effect of 3-nitropropionic acid on behavioral dysfunction, neuron loss and gliosis in the brain of adult male rats: The case of prefrontal cortex, hippocampus and the cerebellum.
Autorzy :
Torabi A; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
Joneidi M; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
Mohammadzadeh I; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abdollahifar MA; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Khatmi A; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ezi S; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Moghaddam MH; Department of Anatomical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Rafiei R; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Kahrizirad F; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Norozian M; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
Aliaghaei A; Neuroscience Lab, Department of Cell Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: .
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Źródło :
Toxicon : official journal of the International Society on Toxinology [Toxicon] 2020 Aug; Vol. 183, pp. 44-50. Date of Electronic Publication: 2020 May 26.
Typ publikacji :
Journal Article
MeSH Terms :
Mycotoxins/*toxicity
Nitro Compounds/*toxicity
Propionates/*toxicity
Animals ; Brain ; Cerebellum/drug effects ; Gliosis ; Hippocampus/drug effects ; Male ; Prefrontal Cortex/drug effects ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Influence of 3-nitropropionic acid on physiological and behavioral responses in zebrafish larvae and adults.
Autorzy :
Wiprich MT; Programa de Pós-Graduação em Medicina e Ciências da Saúde, Escola de Medicina, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil; Laboratório de Neuroquímica e Psicofarmacologia, Escola de Ciências da Saúde e da Vida, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Zanandrea R; Programa de Pós-Graduação em Medicina e Ciências da Saúde, Escola de Medicina, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil; Laboratório de Neuroquímica e Psicofarmacologia, Escola de Ciências da Saúde e da Vida, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Altenhofen S; Programa de Pós-Graduação em Medicina e Ciências da Saúde, Escola de Medicina, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil; Laboratório de Neuroquímica e Psicofarmacologia, Escola de Ciências da Saúde e da Vida, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil; Instituto Nacional de Ciência e Tecnologia em Doenças Cerebrais, Excitotoxicidade e Neuroproteção, Porto Alegre, RS, Brazil.
Bonan CD; Programa de Pós-Graduação em Medicina e Ciências da Saúde, Escola de Medicina, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil; Laboratório de Neuroquímica e Psicofarmacologia, Escola de Ciências da Saúde e da Vida, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brazil; Instituto Nacional de Ciência e Tecnologia em Doenças Cerebrais, Excitotoxicidade e Neuroproteção, Porto Alegre, RS, Brazil. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP [Comp Biochem Physiol C Toxicol Pharmacol] 2020 Aug; Vol. 234, pp. 108772. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
USP14 as a Therapeutic Target Against Neurodegeneration: A Rat Brain Perspective.
Autorzy :
Banerjee C; Department of Cell Biology and Physiology, CSIR-Indian Institute of Chemical Biology-TRUE, Kolkata, India.; CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Roy M; Department of Cell Biology and Physiology, CSIR-Indian Institute of Chemical Biology-TRUE, Kolkata, India.; CSIR-Indian Institute of Chemical Biology, Kolkata, India.; Academy of Scientific and Innovative Research (AcSIR), CSIR- Human Resource Development Centre, Ghaziabad, India.
Mondal R; Department of Cell Biology and Physiology, CSIR-Indian Institute of Chemical Biology-TRUE, Kolkata, India.; CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Chakraborty J; Department of Cell Biology and Physiology, CSIR-Indian Institute of Chemical Biology-TRUE, Kolkata, India.; CSIR-Indian Institute of Chemical Biology, Kolkata, India.
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Źródło :
Frontiers in cell and developmental biology [Front Cell Dev Biol] 2020 Jul 31; Vol. 8, pp. 727. Date of Electronic Publication: 2020 Jul 31 (Print Publication: 2020).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Early Reactive A1 Astrocytes Induction by the Neurotoxin 3-Nitropropionic Acid in Rat Brain.
Autorzy :
Lopez-Sanchez C; Instituto de Biomarcadores de Patologias Moleculares, Universidad de Extremadura, 06006 Badajoz, Spain.; Departamento de Anatomia y Embriologia Humana, Facultad de Medicina, Universidad de Extremadura, 06006 Badajoz, Spain.
Garcia-Martinez V; Instituto de Biomarcadores de Patologias Moleculares, Universidad de Extremadura, 06006 Badajoz, Spain.; Departamento de Anatomia y Embriologia Humana, Facultad de Medicina, Universidad de Extremadura, 06006 Badajoz, Spain.
Poejo J; Instituto de Biomarcadores de Patologias Moleculares, Universidad de Extremadura, 06006 Badajoz, Spain.
Garcia-Lopez V; Instituto de Biomarcadores de Patologias Moleculares, Universidad de Extremadura, 06006 Badajoz, Spain.; Departamento de Anatomia y Embriologia Humana, Facultad de Medicina, Universidad de Extremadura, 06006 Badajoz, Spain.; Departamento de Enfermeria, Facultad de Medicina, Universidad de Extremadura, 06006 Badajoz, Spain.
Salazar J; Instituto de Biomarcadores de Patologias Moleculares, Universidad de Extremadura, 06006 Badajoz, Spain.; Departamento de Quimica, Universidad Nacional Autonoma de Nicaragua-Leon, Leon 21000, Nicaragua.
Gutierrez-Merino C; Instituto de Biomarcadores de Patologias Moleculares, Universidad de Extremadura, 06006 Badajoz, Spain.; Departamento de Bioquimica y Biología Molecular y Genetica, Facultad de Ciencias, Universidad de Extremadura, 06006 Badajoz, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 May 20; Vol. 21 (10). Date of Electronic Publication: 2020 May 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Anemarrhenae asphodeloides rhizoma Extract Enriched in Mangiferin Protects PC12 Cells against a Neurotoxic Agent-3-Nitropropionic Acid.
Autorzy :
Piwowar A; Department of Toxicology, Wroclaw Medical University, 211 50556 Borowska, Poland.
Rembiałkowska N; Department of Molecular and Cellular Biology, Wroclaw Medical University, 211A 50556 Borowska, Poland.
Rorbach-Dolata A; Department of Toxicology, Wroclaw Medical University, 211 50556 Borowska, Poland.
Garbiec A; Department of Developmental Biology, Institute of Experimental Biology, University of Wroclaw, ul. H. 21 50335 Sienkiewicza, Poland.
Ślusarczyk S; Department of Pharmaceutical Biology and Botany, Wroclaw Medical University, 211 50556 Borowska, Poland.
Dobosz A; Department of Basic Medical Sciences, Wroclaw Medical University, 211 50556 Borowska, Poland.
Długosz A; Department of Toxicology, Wroclaw Medical University, 211 50556 Borowska, Poland.
Marchewka Z; Department of Toxicology, Wroclaw Medical University, 211 50556 Borowska, Poland.
Matkowski A; Department of Pharmaceutical Biology and Botany, Wroclaw Medical University, 211 50556 Borowska, Poland.
Saczko J; Department of Molecular and Cellular Biology, Wroclaw Medical University, 211A 50556 Borowska, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Apr 04; Vol. 21 (7). Date of Electronic Publication: 2020 Apr 04.
Typ publikacji :
Journal Article
MeSH Terms :
Anemarrhena/*chemistry
Neuroprotective Agents/*pharmacology
Nitro Compounds/*adverse effects
PC12 Cells/*cytology
Propionates/*adverse effects
Xanthones/*pharmacology
Animals ; Apoptosis/drug effects ; Dose-Response Relationship, Drug ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/pharmacology ; Molecular Structure ; Neuroprotective Agents/chemistry ; PC12 Cells/drug effects ; Rats ; Rhizome/chemistry ; Time Factors ; Xanthones/chemistry
Czasopismo naukowe
Tytuł :
Exposure to 3-Nitropropionic Acid Mitochondrial Toxin Induces Tau Pathology in Tangle-Mouse Model and in Wild Type-Mice.
Autorzy :
Lahiani-Cohen I; The Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Touloumi O; B' Department of Neurology, AHEPA University Hospital, Thessaloniki, Greece.
Lagoudaki R; B' Department of Neurology, AHEPA University Hospital, Thessaloniki, Greece.
Grigoriadis N; B' Department of Neurology, AHEPA University Hospital, Thessaloniki, Greece.
Rosenmann H; The Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
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Źródło :
Frontiers in cell and developmental biology [Front Cell Dev Biol] 2020 Jan 14; Vol. 7, pp. 321. Date of Electronic Publication: 2020 Jan 14 (Print Publication: 2019).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Taurine Improves Lipid Metabolism and Increases Resistance to Oxidative Stress.
Autorzy :
Wang Z; Biomedical Gerontology Laboratory, Faculty of Human Sciences, Waseda University.
Ohata Y; Biomedical Gerontology Laboratory, Faculty of Human Sciences, Waseda University.
Watanabe Y; Biomedical Gerontology Laboratory, Faculty of Human Sciences, Waseda University.
Yuan Y; Biomedical Gerontology Laboratory, Faculty of Human Sciences, Waseda University.
Yoshii Y; Biomedical Gerontology Laboratory, Faculty of Human Sciences, Waseda University.
Kondo Y; Biomedical Gerontology Laboratory, Faculty of Human Sciences, Waseda University.
Nishizono S; Department of Applied Microbial Technology, Faculty of Biotechnology and Life Science, Sojo University.
Chiba T; Biomedical Gerontology Laboratory, Faculty of Human Sciences, Waseda University.
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Źródło :
Journal of nutritional science and vitaminology [J Nutr Sci Vitaminol (Tokyo)] 2020; Vol. 66 (4), pp. 347-356.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Vildagliptin Attenuates Huntington's Disease through Activation of GLP-1 Receptor/PI3K/Akt/BDNF Pathway in 3-Nitropropionic Acid Rat Model.
Autorzy :
Sayed NH; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Governorate, Giza, Egypt.
Fathy N; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Governorate, Giza, Egypt. .
Kortam MA; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Governorate, Giza, Egypt.
Rabie MA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Governorate, Giza, Egypt.
Mohamed AF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Governorate, Giza, Egypt.
Kamel AS; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Governorate, Giza, Egypt.
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Źródło :
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics [Neurotherapeutics] 2020 Jan; Vol. 17 (1), pp. 252-268.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Lercanidipine boosts the efficacy of mesenchymal stem cell therapy in 3-NP-induced Huntington's disease model rats via modulation of the calcium/calcineurin/NFATc4 and Wnt/β-catenin signalling pathways.
Autorzy :
Elbaz EM; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Helmy HS; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
El-Sahar AE; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Saad MA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt; School of Pharmacy, Newgiza University, Cairo, Egypt.
Sayed RH; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt. Electronic address: .
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Źródło :
Neurochemistry international [Neurochem Int] 2019 Dec; Vol. 131, pp. 104548. Date of Electronic Publication: 2019 Sep 17.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium Channel Blockers/*therapeutic use
Dihydropyridines/*therapeutic use
Huntington Disease/*therapy
Mesenchymal Stem Cell Transplantation/*methods
Signal Transduction/*drug effects
Animals ; Behavior, Animal/drug effects ; Calcineurin/drug effects ; Calcium Signaling/drug effects ; Cytosol/drug effects ; Cytosol/metabolism ; Huntington Disease/chemically induced ; Huntington Disease/drug therapy ; Male ; NFATC Transcription Factors/drug effects ; Nerve Tissue Proteins/drug effects ; Nitro Compounds ; Propionates ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Rats ; Rats, Wistar ; Tumor Necrosis Factor-alpha/metabolism ; Wnt Signaling Pathway/drug effects ; bcl-2-Associated X Protein/metabolism ; beta Catenin/drug effects
Czasopismo naukowe
Tytuł :
Long-lasting changes in the cochlear K+ recycling structures after acute energy failure.
Autorzy :
Takiguchi Y; Department of Otolaryngology, Eiju General Hospital, 2-23-16 Higashi-ueno, Taito-ku, Tokyo 110-8645, Japan; The Laboratory of Auditory Disorders, National Institute of Sensory Organs, National Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-ku, Tokyo, 152-8902, Japan; Department of Otolaryngology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Sun GW
Ogawa K
Matsunaga T
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Źródło :
Neuroscience research [Neurosci Res] 2013 Sep-Oct; Vol. 77 (1-2), pp. 33-41. Date of Electronic Publication: 2013 Jul 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Energy Metabolism*
Brain Stem/*physiopathology
Cochlea/*pathology
Hearing Loss, Sensorineural/*pathology
Potassium/*metabolism
Animals ; Brain Stem/drug effects ; Cochlea/metabolism ; Connexin 26 ; Connexins/metabolism ; Hearing Loss, Sensorineural/chemically induced ; Hearing Loss, Sensorineural/metabolism ; Hearing Loss, Sensorineural/physiopathology ; Intramolecular Oxidoreductases/metabolism ; Lipocalins/metabolism ; Male ; Nitro Compounds/pharmacology ; Potassium Channels, Inwardly Rectifying/metabolism ; Propionates/pharmacology ; Rats ; Rats, Sprague-Dawley ; Sodium-Potassium-Exchanging ATPase/metabolism ; Solute Carrier Family 12, Member 2/metabolism
Czasopismo naukowe
Tytuł :
Another win for endothelial progenitor cells: Endothelial progenitor cell-derived conditioned medium promotes proliferation and exerts neuroprotection in cultured neuronal progenitor cells.
Autorzy :
Sadanandan N; Department of Neurosurgery and Brain Repair, College of Medicine, University of South Florida Morsani, Tampa, FL, USA.
Di Santo S; Department of Neurosurgery, Neurocenter and Regenerative Neuroscience Cluster, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Widmer HR; Department of Neurosurgery, Neurocenter and Regenerative Neuroscience Cluster, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
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Źródło :
Brain circulation [Brain Circ] 2019 Sep 30; Vol. 5 (3), pp. 106-111. Date of Electronic Publication: 2019 Sep 30 (Print Publication: 2019).
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Gintonin, a ginseng-derived ingredient, as a novel therapeutic strategy for Huntington's disease: Activation of the Nrf2 pathway through lysophosphatidic acid receptors.
Autorzy :
Jang M; Department of Convergence Medical Science, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
Choi JH; Department of Convergence Medical Science, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea; Department of Science in Korean Medicine and Brain Korea 21 Plus Program, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Chang Y; Department of Convergence Medical Science, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea; Department of Science in Korean Medicine and Brain Korea 21 Plus Program, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Lee SJ; Department of Neuroscience and Physiology, School of Dentistry, Seoul National University, Seoul 08826, Republic of Korea.
Nah SY; Ginsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine and Bio/Molecular Informatics Center, Konkuk University, Seoul 05029, Republic of Korea.
Cho IH; Department of Convergence Medical Science, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea; Department of Science in Korean Medicine and Brain Korea 21 Plus Program, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea; Institute of Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea. Electronic address: .
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Źródło :
Brain, behavior, and immunity [Brain Behav Immun] 2019 Aug; Vol. 80, pp. 146-162. Date of Electronic Publication: 2019 Mar 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
NF-E2-Related Factor 2/*metabolism
Plant Extracts/*pharmacology
Receptors, Lysophosphatidic Acid/*metabolism
Animals ; Anti-Inflammatory Agents/pharmacology ; Cell Death/drug effects ; Corpus Striatum/immunology ; Corpus Striatum/metabolism ; Disease Models, Animal ; Huntington Disease/drug therapy ; Huntington Disease/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Mitogen-Activated Protein Kinases/metabolism ; NF-kappa B/metabolism ; Neurons/metabolism ; Neuroprotective Agents/pharmacology ; Panax ; Plant Extracts/metabolism ; Receptors, Lysophosphatidic Acid/drug effects ; Receptors, Lysophosphatidic Acid/physiology ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
[Determination of 3-nitropropionic acid in moldy sugarcane by gel filtration-high performance liquid chromatography].
Autorzy :
Wu Y; Xuzhou Center for Disease Control and Prevention, Xuzhou 221000, China.
Zhang J; Xuzhou Center for Disease Control and Prevention, Xuzhou 221000, China.
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Źródło :
Wei sheng yan jiu = Journal of hygiene research [Wei Sheng Yan Jiu] 2019 May; Vol. 48 (3), pp. 474-481.
Typ publikacji :
Journal Article
MeSH Terms :
Saccharum*
Chromatography, High Pressure Liquid ; Nitro Compounds ; Propionates
Czasopismo naukowe

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