Temat: "3-Nitropropionic acid" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Neuroprotectant Effects of Hibiscetin in 3-Nitropropionic Acid-Induced Huntington's Disease via Subsiding Oxidative Stress and Modulating Monoamine Neurotransmitters in Rats Brain.
Autorzy:: Mahdi WA; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
AlGhamdi SA; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Alghamdi AM; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Imam SS; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alshehri S; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Almaniea MA; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Hajjar BM; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Al-Abbasi FA; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Sayyed N; School of Pharmacy, Glocal University, Saharanpur 247121, India.
Kazmi I; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Feb 01; Vol. 28 (3). Date of Electronic Publication: 2023 Feb 01.
Typ publikacji:: Journal Article
MeSH Terms:: Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Huntington Disease*/chemically induced
Huntington Disease*/drug therapy
Rats ; Animals ; Rats, Wistar ; Oxidative Stress ; Nitro Compounds/pharmacology ; Propionates/pharmacology ; Neurotransmitter Agents/pharmacology ; Body Weight ; Brain

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Skocz do pozycji: 2.

Tytuł:: Filgrastim, a Recombinant Form of Granulocyte Colony-stimulating Factor, Ameliorates 3-nitropropionic Acid and Haloperidol-induced Striatal Neurotoxicity in Rats.
Autorzy:: Rahi V; Department of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda, Punjab, India.
Ram P; Department of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda, Punjab, India.
Kumar P; Department of Pharmacology, Central University of Punjab, Bathinda, Punjab, India. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2022 Dec; Vol. 40 (6), pp. 2089-2102. Date of Electronic Publication: 2022 Nov 17.
Typ publikacji:: Journal Article
MeSH Terms:: Huntington Disease*/chemically induced
Movement Disorders*/drug therapy
Movement Disorders*/etiology
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Neurotoxicity Syndromes*/drug therapy
Neurotoxicity Syndromes*/prevention & control
Animals ; Rats ; Filgrastim/adverse effects ; Granulocyte Colony-Stimulating Factor/therapeutic use ; Haloperidol/toxicity ; Nitro Compounds/toxicity ; Propionates ; Rats, Wistar

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Skocz do pozycji: 3.

Tytuł:: Naringenin mitigates behavioral alterations and provides neuroprotection against 3-nitropropinoic acid-induced Huntington's disease like symptoms in rats.
Autorzy:: Salman M; Department of Toxicology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi, India.
Sharma P; Department of Toxicology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi, India.
Alam MI; Department of Medical Physiology, HIMSR, Jamia Hamdard, New Delhi, India.
Tabassum H; Division of Basic Medical Sciences, Indian Council of Medical Research, Ministry of Health and Family Welfare, Govt. of India, V. Ramalingaswamy Bhawan, New Delhi, India.
Parvez S; Department of Toxicology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi, India.; Pokaż więcej
Źródło:: Nutritional neuroscience [Nutr Neurosci] 2022 Sep; Vol. 25 (9), pp. 1898-1908. Date of Electronic Publication: 2021 Apr 15.
Typ publikacji:: Journal Article
MeSH Terms:: Flavanones*/therapeutic use
Huntington Disease*/chemically induced
Huntington Disease*/drug therapy
Huntington Disease*/prevention & control
Neuroprotective Agents*/pharmacology
Animals ; Antioxidants/therapeutic use ; Body Weight ; Corpus Striatum ; Disease Models, Animal ; Glial Fibrillary Acidic Protein/metabolism ; Monoamine Oxidase/metabolism ; Monoamine Oxidase/pharmacology ; Monoamine Oxidase/therapeutic use ; Motor Activity ; Neuroprotection ; Nitro Compounds/toxicity ; Propionates/toxicity ; Rats ; Rats, Wistar ; Serotonin/metabolism

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Skocz do pozycji: 4.

Tytuł:: Anti-Huntington's Effect of Rosiridin via Oxidative Stress/AchE Inhibition and Modulation of Succinate Dehydrogenase, Nitrite, and BDNF Levels against 3-Nitropropionic Acid in Rodents.
Autorzy:: Afzal M; Department of Pharmacology, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.
Sayyed N; School of Pharmacy, Glocal University, Saharanpur 247121, India.
Alharbi KS; Department of Pharmacology, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.
Alzarea SI; Department of Pharmacology, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.
Alshammari MS; Department of Pharmacy Practice, Unaizah College of Pharmacy, Qassim University, Buraydah 52571, Saudi Arabia.
Alomar FA; Department of Pharmacology and Toxicology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.
Alenezi SK; Department of Pharmacology and Toxicology, Unaizah College of Pharmacy, Qassim University, Buraydah 52571, Saudi Arabia.
Quazi AM; Department of Pharmacology, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.
Alzarea AI; Department of Clinical Pharmacy, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.
Kazmi I; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2022 Jul 23; Vol. 12 (8). Date of Electronic Publication: 2022 Jul 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Brain-Derived Neurotrophic Factor*/blood
Huntington Disease*
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Succinate Dehydrogenase*/metabolism
Acetylcholinesterase ; Animals ; Motor Activity ; Nitrites/metabolism ; Nitro Compounds ; Oxidative Stress ; Propionates ; Rats ; Rats, Wistar

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Skocz do pozycji: 5.

Tytuł:: Restoration of BDNF, DARPP32, and D2R Expression Following Intravenous Infusion of Human Immature Dental Pulp Stem Cells in Huntington's Disease 3-NP Rat Model.
Autorzy:: Wenceslau CV; Cellavita Pesquisas Científicas Ltda., Valinhos 13271-650, SP, Brazil.
de Souza DM; Genetics Laboratory, Instituto Butantan, São Paulo 05503-900, SP, Brazil.
Mambelli-Lisboa NC; Genetics Laboratory, Instituto Butantan, São Paulo 05503-900, SP, Brazil.
Ynoue LH; Azidus Brasil, Valinhos 13271-130, SP, Brazil.
Araldi RP; Cellavita Pesquisas Científicas Ltda., Valinhos 13271-650, SP, Brazil.; Genetics Laboratory, Instituto Butantan, São Paulo 05503-900, SP, Brazil.; Programa de Pós-graduação em Biologia Estrutural e Funcional, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo 04023-062, SP, Brazil.
da Silva JM; Azidus Brasil, Valinhos 13271-130, SP, Brazil.
Pagani E; Azidus Brasil, Valinhos 13271-130, SP, Brazil.
Haddad MS; Hospital das Clínicas, Faculdade de Medicina, Universidade Estadual de Campinas (UNICAMP), Campinas 13083-872, SP, Brazil.
Kerkis I; Genetics Laboratory, Instituto Butantan, São Paulo 05503-900, SP, Brazil.; Programa de Pós-graduação em Biologia Estrutural e Funcional, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo 04023-062, SP, Brazil.; Pokaż więcej
Źródło:: Cells [Cells] 2022 May 17; Vol. 11 (10). Date of Electronic Publication: 2022 May 17.
Typ publikacji:: Journal Article
MeSH Terms:: Brain-Derived Neurotrophic Factor*/genetics
Dopamine and cAMP-Regulated Phosphoprotein 32*/genetics
Huntington Disease*/genetics
Huntington Disease*/therapy
Stem Cell Transplantation*
Stem Cells*/cytology
Animals ; Dental Pulp/cytology ; Disease Models, Animal ; Humans ; Infusions, Intravenous ; Rats

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Skocz do pozycji: 6.

Tytuł:: Neuroprotective effect of solanesol against 3-nitropropionic acid-induced Huntington's disease-like behavioral, biochemical, and cellular alterations: Restoration of coenzyme-Q10-mediated mitochondrial dysfunction.
Autorzy:: Mehan S; Department of Pharmacology, ISF College of Pharmacy, Moga, Punjab, India.
Monga V; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga, Punjab, India.
Rani M; Department of Pharmacology, Rajendra Institute of Technology and Sciences, Sirsa, Haryana, India.
Dudi R; Department of Pharmacology, Rajendra Institute of Technology and Sciences, Sirsa, Haryana, India.
Ghimire K; Department of Pharmaceutical Sciences, PDM University, Bahadurgarh, Haryana, India.; Pokaż więcej
Źródło:: Indian journal of pharmacology [Indian J Pharmacol] 2018 Nov-Dec; Vol. 50 (6), pp. 309-319.
Typ publikacji:: Journal Article
MeSH Terms:: Behavior, Animal/*drug effects
Brain/*drug effects
Huntington Disease/*drug therapy
Mitochondria/*drug effects
Neuroprotective Agents/*therapeutic use
Terpenes/*therapeutic use
Ubiquinone/*analogs & derivatives
Animals ; Brain/metabolism ; Brain/pathology ; Disease Models, Animal ; Huntington Disease/chemically induced ; Huntington Disease/metabolism ; Huntington Disease/pathology ; Male ; Maze Learning/drug effects ; Mitochondria/metabolism ; Motor Activity/drug effects ; Muscle Strength/drug effects ; Nitro Compounds ; Propionates ; Rats, Wistar ; Ubiquinone/metabolism