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Wyświetlanie 1-1 z 1
Tytuł :
Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor response.
Autorzy :
Baeuerle PA; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA.
Ding J; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA.
Patel E; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA.
Thorausch N; Department of Immunology, Faculty of Biology, BIOSS Center for Biological Signalling Studies, CIBSS-Centre for Integrative Biological Signalling Studies and Centre for Chronic Immunodeficiency CCI, University of Freiburg, Schänzlestraβe 18, Freiburg, 79104, Germany.
Horton H; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA.
Gierut J; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA.
Scarfo I; Cellular Immunotherapy Program, Massachusetts General Hospital Cancer Center and Harvard Medical School, Bldg. 149 13th Street, Charlestown, MA, USA.
Choudhary R; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA.
Kiner O; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA.
Krishnamurthy J; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA.
Le B; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA.
Morath A; Department of Immunology, Faculty of Biology, BIOSS Center for Biological Signalling Studies, CIBSS-Centre for Integrative Biological Signalling Studies and Centre for Chronic Immunodeficiency CCI, University of Freiburg, Schänzlestraβe 18, Freiburg, 79104, Germany.
Baldeviano GC; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA.
Quinn J; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA.
Tavares P; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA.
Wei Q; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA.
Weiler S; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA.
Maus MV; Cellular Immunotherapy Program, Massachusetts General Hospital Cancer Center and Harvard Medical School, Bldg. 149 13th Street, Charlestown, MA, USA.
Getts D; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA.
Schamel WW; Department of Immunology, Faculty of Biology, BIOSS Center for Biological Signalling Studies, CIBSS-Centre for Integrative Biological Signalling Studies and Centre for Chronic Immunodeficiency CCI, University of Freiburg, Schänzlestraβe 18, Freiburg, 79104, Germany.
Hofmeister R; TCR² Therapeutics, Inc., 100 Binney Street, Cambridge, MA, 02142, USA. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2019 May 07; Vol. 10 (1), pp. 2087. Date of Electronic Publication: 2019 May 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunotherapy, Adoptive/*methods
Neoplasms/*therapy
Receptors, Antigen, T-Cell/*immunology
Receptors, Artificial/*immunology
Single-Chain Antibodies/*immunology
T-Lymphocytes/*immunology
Animals ; Antigens, CD19/immunology ; Antigens, Neoplasm/immunology ; Cell Line, Tumor ; Female ; Humans ; Mice ; Mice, Inbred NOD ; Neoplasms/immunology ; Primary Cell Culture ; Protein Domains ; Receptors, Antigen, T-Cell/genetics ; Receptors, Artificial/genetics ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/immunology ; Single-Chain Antibodies/genetics ; Treatment Outcome ; Xenograft Model Antitumor Assays
Czasopismo naukowe
    Wyświetlanie 1-1 z 1

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